NASH clinical research network launches trial for treatment of liver disease in children
... methods used to assess fatty liver, which include serum enzyme readings, ultrasound, and magnetic resonanc...bout 23 percent of obese 17-year-olds had abnormal serum enzyme levels, an indicator of NAFLD. The major feature in NAFLD is the accumulation of fat in the l...Liver CRP production linked to atherosclerosis
...y form atherosclerotic plaques in response to high serum cholesterol, and rabbit CRP shares 70% homology wi...therosclerotic plaques. Upon further examination, serum CRP levels were found to positively correlate with plaque size. CRP was found in plaques of various ...High fat diet alters hepatic immune system in mice
... The mice were then sacrificed to obtain liver and serum tissue. The researchers isolated hepatic mononucle...RNA for analysis. Finally, they measured levels of serum alanine aminotransferases (ALT), a marker of liver injury. The mice on high fat diets gained signif...Tip sheet Annals of Internal Medicine, Oct. 4, 2005, issue
..., physicians should perform blood tests to measure serum ferritin and transferrin saturation tests. Hemochromatosis can increase iron deposits in body organs, which can cause serious liver damage such as cirrhosis and liver cancer, diabetes, heart failure, arthritis, and skin discoloration. Patients who h...Use of kidney paired donation for incompatible donors could expand donor pool
...ents have functioning grafts with a median 6-month serum creatinine level of 1.2 mg/dL. There were no instances of antibody-mediated rejection despite the inclusion of 5 patients who were highly sensitized to HLA antigens due to previous exposure to foreign tissue. Four patients developed acute cellular re...Researchers find multiple proteins that stick to medical devices
... Louis have found a new role for the blood protein serum amyloid P in the body's response to medical materi...al of Biomedical Materials Research. New role for serum amyloid P By casting a wider net, they found one particular protein on the materials in large amoun...Total cholesterol level among US adults continues to decline
... this period. The age-adjusted geometric [average] serum triglyceride level of adults 20 years or older inc...justed percentage of adults 20 years or older with serum total cholesterol level of at least 240 mg/dL (6.22 mmol/L or greater) decreased from 20 percent to...Therapeutic vaccine for ovarian cancer in clinical trials
...on as measured by the decline in or plateau of the serum marker, CA-125. Secondary end points include progression-free survival, immune response, any adverse events, any interruptions or withdrawal from treatment and performance status. Analysis of early results on the progress of patients already undergo...... observed increases in circulating blood levels of serum cytokines. They are now finishing a study in which they are examining blood collected from humans diagnosed with repetitive strain injuries for these cytokines. Positive findings could aid earlier diagnosis and therefore earlier treatment....Cholesterol levels and use of lipid-lowering drugs are not associated with breast cancer risk
... associations of statins, lipid-lowering drugs and serum cholesterol levels (blood levels of cholesterol) w...t. There was no association between reported total serum cholesterol levels and breast cancer risk in either pre-menopausal or post-menopausal women. "In su...Vitamin D status appears more important than high calcium intake for maintaining calcium metabolism
...iversal consensus has been reached regarding which serum values constitute sufficiency. An inverse relationship between serum 25-hydroxyvitamin D and serum parathyroid hormone (PTH) is well established. Parathyroid hormone is ...Mayo Clinic Cancer Center finds better predictors for outcomes after radical prostatectomy
...n we previously thought, and we don't have another serum marker to help us," says Michael Blute, M.D., Mayo Clinic urologist and lead investigator of the study. "It was important for us to find other ways to look at PSA data and translate that into information that will save lives, and I believe we have d...Higher placental weight associated with increased maternal breast cancer risk
... in breast carcinogenesis is well established, and serum estrogen levels are at least 10 times higher during pregnancy compared with other times of life," the authors write. "In addition, placental weight appears to be a better indicator of the hormonal milieu than birth weight or other included birth para...Substituting carbohydrates in diet with protein or unsaturated fats may reduce cardiovascular risk
...mendations are to lower blood pressure and improve serum lipids, two of the primary determinants of CVD ris...) study compared the effects on blood pressure and serum lipids of three healthful diets: a carbohydrate-rich diet, similar to the DASH diet (Dietary Approac...Do increased levels of testosterone play a role in Sudden Infant Death Syndrome?
...sted estrogen and testosterone levels in the blood serum of 127 infants who had died of SIDS and 42 infants who had died of other causes of unexpected infant death. They found that the testosterone levels in the male SIDS infants were 120% higher than in male non-SIDS infants and 50% higher in female SIDS...Mental stress may be another culprit in raising cholesterol levels in healthy adults
...asons why acute stress responses may raise fasting serum lipids. One possibility may be that stress encourages the body to produce more energy in the form of metabolic fuels fatty acids and glucose. These substances require the liver to produce and secrete more LDL, which is the principal carrier of chole...Higher dose formulation of FOSRENOL approved to reduce serum phosphorus in esrd patients
...ysis patients. FOSRENOL(R) is indicated to reduce serum phosphorus in patients with ESRD. "As a result...patients treated with FOSRENOL(R) showed sustained serum phosphorus reduction in a majority of patients. Managing Hyperphosphatemia Phosphorus, a...Agricultural workers at increased risk for infection with animal flu viruses
...ay and graduate student Kendall P. Myers, examined serum samples taken from four adult populations in Iowa ...upational pig exposure. The researchers tested the serum samples for antibodies to several then-current swine and human influenza A viruses. The results sho...Moderate to severe sleep-disordered breathing can lead to stroke
...phy), along with measurement of blood pressure and serum cholesterol levels, together with a check of other stroke risk factors such as body mass index. Among the 1,475 participants, 76 percent (1,121) did not have sleep-disordered breathing (less than 5 "events" per hour), 17 percent (251) had a mild diso......eir investigation, the researchers collected blood serum samples from 31 RA patients. Between the ages of ...iving different treatments. For control purposes, serum samples were also collected from 41 patients with other inflammatory joint diseases, including osteo...