USC researchers show that molecular markers predict tumor recurrence
...or recurrence, the study shows. The results also show that patients with stage II colorectal cancer seem to have a different molecular profile for tumor recurrence. However, further trials are needed to validate the preliminary data, Lurje says. The findings may help oncologists target patients who w...Benefits of trastuzumab are lasting, reducing both HER2 + breast cancer deaths and recurrence
... the therapy, says Dr. Perez. The four-year data show a persistent benefit compared to what was seen at two years, according to Dr. Perez, with trastuzumab combined with chemotherapy continuing to outperform chemotherapy treatment alone. The first joint analysis of these two trials, published Oct. 20, 2...Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
...has some flaws. He thinks that the groups findings show that CTCs can be a stronger marker. The other exciting aspect is in looking at men with earlier stage prostate cancer, he says. One in four men may have circulating tumor cells at an early stage of prostate cancer. If we can identify those patients...Researchers call for investigation into links between khat use and psychiatric disorders
...cial science journal, Social Science and Medicine, show that whilst khat use appears to exacerbate existing psychological problems, there is not currently, any clear evidence which indicates that khat use is a catalyst for the development of mental illness. Commonly used by around 10 million people in ...U-M study finds lymphoma drug effective over long term
...ents with relapsed follicular lymphoma. These data show Bexxar is particularly effective when used as a frontline treatment," says Mark Kaminski, M.D., professor of internal medicine at the U-M Medical School. Kaminski will present these results June 4 at the American Society of Clinical Oncology annual m...Benefits of school-based fitness programs fade after summer
...nsupervised activity, the authors note. These data show that in children, efforts to improve insulin sensitivity and reduce risk of type 2 diabetes mellitus and other morbidities of insulin resistance should include exercise intervention in a sustained manner to improve cardiovascular fitness throughout t...Antipsychotic drugs increase risk of death in older people with dementia
...red." An editorial writer says the findings do not show that having health insurance necessarily improves health care (Editorial p. 814). But the writer says that many other studies in the past quarter century "provide convincing support that health insurance improves health outcomes." So, the writer asks...Bias in statin trials, failure to control malaria, and more
...alifornia, San Francisco argue that their findings show that the type of sponsorship available for randomi...ludisme, Ouagadougou, Burkina Faso) and colleagues show how this lack of coordination is preventing health professionals in Burkina Faso from getting life-s...Revlimid data presented at ASCO stands to change the way physicians treat multiple myeloma
...time at ASCO, the complete data were presented and show that patients in all age ranges benefit from Revlimid with the low dose dexamethasone (LDD). Patients under age 65 had the greatest one year survival: 98% with Revlimid/LDD vs 90% with Revlimid/high dose dexamethasone (HDD). But patients o...Study finds difference in survival rates among white and black women with advanced breast cancer
...ciety of Clinical Oncology (ASCO), is the first to show that improvements in breast cancer survival only benefit white women and that the disparity between black and white breast cancer patients is widening. The study evolved as a follow-up to recent research of Sharon Giordano, M.D., assistant professo...MUHC-led international team identifies gene responsible for blindness in infants and children
...C) funded this research. Discoveries like this one show us that treatments and cures are in sight. The Foundation Fighting Blindness in Canada is proud to fund quality vision research at the MUCH that is giving hope to families affected by blindness, says Sharon Colle, National Executive Director of the F...GSK's Pazopanib shows positive results in patients with advanced renal cell carcinoma
... The high response rates seen so far in this study show clear clinical activity in advanced or metastatic renal cell carcinoma, and a number of ongoing studies also demonstrate therapeutic promise in several other tumor types. The most frequent adverse events (AEs) were diarrhea, fatigue, hair color ch...GSK's Pazopanib shows positive results in patients with advanced RCC and ovarian cancer
... The high response rates seen so far in this study show clear clinical activity in advanced or metastatic renal cell carcinoma, and a number of ongoing studies also demonstrate therapeutic promise in several other tumor types. The most frequent adverse events (AEs) were diarrhea, fatigue, hair color ch...VEGF Trap shows activity in patients with advanced ovarian cancer
...national Phase II trial of VEGF Trap (aflibercept) show activity in patients with recurrent epithelial ovarian cancer (EOC) who had received three or four prior chemotherapy regimens and had become resistant to platinum-based chemotherapy agents. The findings, which are being presented today at the Americ...OHSU Cancer Institute shows findings of immunotherapy vaccine in prostate cancer patients
.../ml, the primary endpoint of the study, but it did show a prolongation in prostate-specific antigen doubling time (PSADT). In addition, there was a trend observed in slowing the time to metastatic disease for patients who received sipuleucel-T compared with those who received placebo, but this early tren...Clinical data suggest potential versatility of ALIMTA-based regimens in lung cancer
... At ASCO, researchers will also present data that show ALIMTA as a chemotherapeutic foundation to a variety of approved and investigational targeted anti-cancer agents, including bevacizumab (Avastin), erlotinib (Tarceva), cetuximab (Erbitux) and vandetanib (Zactima). ALIMTA is an antifolate which inte...Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
..., explains Dr. Scalia. "This is the first study to show in animals that this is one of the key mechanisms involved in this proteins anti-inflammatory effect on the vascular system," he notes. "That suggests thinking about either activating the receptors of the target of this protein or administering the f...... be published in August in the journal Aging Cell, show that male mice fed a normal diet and NDGA so far have survived in significantly greater numbers than mice on a normal diet. Scientists measured the difference at a point called median lifespan, when half the control mice had died of natural causes as...Journal Sleep: Longer CPAP use at night can normalize one's daytime functioning
...tions for predicted probabilities of normalization show that more CPAP use is associated with greater relief of sleepiness, no matter how it's measured," said Weaver. According to Dr. Weaver, there are also patients who normalize on therapy with somewhat limited CPAP use. "The actual need for CPAP in ...Brain inflammation may be friend, not foe, for Alzheimer's patients
...ury only adds to the brains woes, the new findings show that the opposite may be true when it comes to Alzheimers disease. Perhaps inflammation is playing the role of protector and is acting more like an ambulance crew helping at the site of a road wreck, not causing the crash. The work suggests that do...