Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
... journal of the American Cancer Society, the study showed that compared to white men, most Asian ethnic groups except South Asians paradoxically have better outcomes despite having worse prognostic profiles at the time of diagnosis. The study is the first to report prostate cancer survival data for Korean,...Survival differences by race most apparent in advanced stages of breast cancer
...val differences. Epidemiology studies have long showed significant racial/ethnic differences in breast ca...erican and 234,313 white) diagnosed from 1988-2003 showed that African American women were more likely than white women to be diagnosed with tumors greater th...Patient-centered approach can backfire
...ut when it comes to treatment decisions. The study showed that when those patients are matched with patient-centered doctors who want them to take a highly active role, they're less likely to follow treatment recommendations or feel satisfied with their care. "There's really a sizable subset of patients w...Regulator of lipid metabolism ensures high quality breast milk
...f the true sustaining forces in life. Yihongs work showed us that this does not simply happen but it is the product of an intricate genetic program that ensures its purity, says Evans. ...Stomach cancer rate set to fall further 25 percent over next decade
...ients during the monitoring period. The figures showed that the rate of new cases fell steadily by between 2.4 and 2.9% a year in women and men, respectively. Dysplasia, which was diagnosed in just over 8500 patients, and atrophic gastritis, which was diagnosed in just over 23,000, both fell by more th...Hispanic drug use rises in US culture
...ure they are acculturating to. The research also showed that acculturated Hispanics were almost twice as likely as non-acculturated Hispanics to report current binge drinking and more than three times as likely to report drinking continuously for days in a row without sobering up, also known as bender dri...Penn study finds pro-death proteins required to regulate healthy immune function
...ced relative to normal cells. Closer investigation showed that the amount and rate of calcium release from intracellular stores was altered in the mutant cells. The inadequate calcium signals were unable to stimulate the mitochondria, which are the energy factories in the cell. Without mitochondrial acti...Nationwide data highlight encouraging trends, 'staggering' costs of ESRD
...ering," Dr. Foley adds. "The most recent estimates showed that Medicare costs for ESRD reached $20.1 billion, while non-Medicare costs rose to $12.4 billion." Costs for the care of ESRD patients now account for 6.7 percent of total Medicare expenditures. In recent years, the research focus has been on chr...Chromatin remodeling complex connected to DNA damage control
... mechanisms. An earlier paper from his lab in Cell showed that INO80 also is involved in DNA damage repair through its connections to a specific phosphorylated histone. "Modification of histones has been studied for some time, now we are moving to understand the modification of something that modifies his...Pathway links inflammation, angiogenesis and breast cancer
...does one get it"" says Hung. Hung and colleagues showed that IKKa phosphorylates CBP in the nucleus, switching CBP's binding preference to the NF"B oncogene, promoting cell growth. Unphosphorylated CBP helps p53 do its job suppressing cancer by forcing defective cells to kill themselves, programmed cell d...NIH scientists target future pandemic strains of H5N1 avian influenza
...a portion called the receptor binding domain. They showed that as few as two mutations to this receptor binding domain could enhance the ability of H5N1 to recognize human cells. Additional mutations would likely need to accumulate for H5N1 to spread more easily from person to person, says Dr. Nabel. The...Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
...wer risk) as those taking aspirin. They say: We showed that the frequency of stroke, arterial embolism, and intracranial haemorrhage was significantly lower in patients on warfarin than in those on aspirin, adding that their results show that warfarin could safely be used much more widely by older people...Despite claims, not all probiotics can treat diarrhea say experts
...was unexpected, they say, because a previous trial showed it to be beneficial in young children admitted to hospital for diarrhoea. They conclude: the efficacy of probiotic preparations for the treatment of acute diarrhoea in children is related to the individual strains of bacteria, and physicians should...A woman who heard voices with her own speech impairments
...in bleed, causing her to lose consciousness. Tests showed she had brain damage covering several lobes and an...again with serious AH and speech difficulties. EEG showed brain seizures, which were successfully treated. When last seen in June 2007, the patient was no lon...Hormone regulates fondness for food
...ther bland (cauliflower, broccoli). The authors showed that in the patients lacking leptin, several areas...e leptin deficient patients, the nucleus accumbens showed this distinctive response (greater for well-liked foods) when patients were hungry (following an ove...Stress may leave your mouth a mess
...iseases; 57% of the studies included in the review showed a positive relationship between periodontal diseases and psychological factors such as stress, distress, anxiety, depression, and loneliness. More research is needed to determine the definitive relationship between stress and periodontal diseases, ...Baby DVDs, videos may hinder, not help, infants' language development
...aper published last spring by the same researchers showed that by 3 months of age 40 percent of infants are regular viewers of television, DVDs or videos and by the age of 2 this number jumps to 90 percent. For both papers, the researchers conducted random telephone interviews with more than 1,000 families...Penn researchers discover novel pathway for increasing 'good' cholesterol
...tes an increased level of HDL-C in the blood. We showed that mice engineered to express high levels of PCSK5A had 50 percent higher HDL-C than control mice, says senior author Daniel J. Rader, MD, the Cooper/McLure Professor of Medicine and Associate Director of the Institute for Translational Medicine a...Obesity linked to hyperparathyroidism in chronic kidney disease
...ber of possible confounding factors. The results showed a significant association between obesity and hype...ciated with higher PTH levels in patients who also showed signs of malnutrition and inflammation," says Dr. Kovesdy. "This finding may be unique to patients ...Metabolic study in mice could lead to 'good cholesterol' boosters
...rtases decreased plasma HDL-C levels in mice. They showed that the metabolic effect of the proprotein conver...ase in EL and a decline in HDL-C. Likewise, they showed that increased activity of proprotein convertases in the liver gives a significant boost to the prot...