Northwestern's cancer genetics program finds gene variants that greatly increase breast cancer risk
...ta variants: TGFBR1*6A and TGFB1 T29C. "Our study shows that TGFBR1*6A is associated with a 120 percent increased risk of breast cancer among women older than 50," says study author Boris Pasche, MD, PhD, FACP, director of Northwestern's Cancer Genetics Program and assistant professor of Medicine at North...Measuring enzymes at end of cancer pathway predicts outcome of Tarceva, Taxol
...ced when CDK2 was given back to the cells, so this shows us that CDK2 is the real target of Tarceva. "This ...cept that describes how Tarceva works, and it also shows that we have a technology that can rapidly measure the true activity of CDK2 in a tumor sample," Uen...NCI's Patient Navigator Research Program: Questions and answers
...nefits of the Patient Navigator Program? Evidence shows that in addition to unequal access to health care, racial/ethnic minorities and underserved populations do not always receive timely, appropriate advice and care when confronted with a cancer diagnosis. Patient navigators can make the difference bet...Columbia study shows women benefit from drug-eluting stents as much as men
...y's Journal of the American College of Cardiology, shows that drug eluting stents are just as effective and... and don't provide the same benefit, but our study shows that there is no scientific basis for this," said the study's principal investigator Alexandra Lansk...Kidney donation program may provide more matches for previously incompatible recipients and donors
...extensive travel to accommodate matches, the study shows how optimization would dramatically reduce the number of pairs required to travel (2.9 percent vs. 18.4 percent). "Even if only 7 percent of patients awaiting kidney transplantation participated in an optimized national KPD program, the health care s...Findings about anti-cancer agent could make it more effective
... division of cancer cells. But his recent research shows that the agent also acts on another enzyme (topoisomerase) that helps cancer cells replicate. "Inhibiting topoisomerase causes DNA strands to break, which is an important mechanism that leads to cell death," said Gmeiner. Knowing more about how the...New research reveals common beliefs about gender differences in health
...ir own sex than for the opposite sex. But, it also shows that males think that men are fitter and females think women are more athletic. Professor Sally Macintyre in the MRC Social and Public Health Sciences Unit at the University of Glasgow analysed responses from 466 women and 353 men, aged 25, 45, and ...Child health teacher numbers at worrying levels
...th care in the UK are being raised as new research shows the numbers of clinical teachers in this field have dropped dramatically in recent years. In a five-year period up to April 2003, there has been a 26% reduction in the number of lecturers and a 7.2% fall in clinical academic staff overall working in...Used in a new way, RNA interference permanently silences key breast cancer gene
...m using this technique in patients, but this study shows that that it may be possible to use RNAi in more than just experiments that silence genes temporarily," says the study's principal investigator, Ralph Arlinghaus, Ph.D., a professor and chair of the Department of Molecular Pathology. Details of the s...New research pinpoints best treatment for stroke
...ral hemorrhage rate was 5.2 percent. The WVU study shows that CT perfusion, which measures blood flow, is v...rfusion and an MRI. Results of the study presented shows that CT perfusion results correspond exceedingly well to MRI studies on several parameters including...Adolescents not receiving health counseling, Stanford study shows
...ompromising behaviors." At the same time, research shows teens tend to trust doctors' advice. So physician visits offer a valuable opportunity to nudge adolescents towards healthy behaviors. In 1992, the AMA called for a shift from teen crisis intervention to problem prevention, and it issued specific guid...Breakthrough for kids with epilepsy
...ome of preschool children who had epilepsy surgery shows that children with a shorter duration of epilepsy, more localized etiologies, and a seizure-free outcome have the best chance for improving their cognitive function 2-3 years after a successful operation," adds Tuxhorn. "The question [now] is to prov...Risk scores may identify young individuals with atherosclerosis
... lifestyle," the authors write. "The present study shows that a risk score, based on simple and inexpensive measurements, has sufficient discrimination that physicians could identify and advise high-risk adolescents and young adults concerning their risk factors (hyperlipidemia, hypertension, smoking, obes...Fatal brain disease holds clues to dementia
...ular area of the brain," Dr Hannan said. "Our work shows that the defective huntingtin gene disrupts how large groups of neurons 'talk' to one another and adjust their wiring in response to stimulation from the environment." "Now we can better understand how a genetic change affects wiring of neurons and ...New portable device developed by Georgia Tech and Emory checks for concussions on the sidelines
...empts to perform the tests. For example, the first shows the wearer a series of shapes with different colors and textures and gives voice instructions. The wearer uses a simple controller (similar to a video game controller) to respond to the commands. The device then measures the wearer's response times a...Revised Bethesda guidelines effective at identifying patients at risk of colorectal cancer
...ting, the use of immunohistochemistry [a test that shows specific antigens in tissues] may help identify a larger proportion of patients with HNPCC," the authors write....Color doppler sonography speeds detection of serious illness in premature infants
... other ultrasound procedures because color Doppler shows the presence or absence of blood flow in the intestines and whether that flow is normal, increased or absent. CDS is also noninvasive and free of ionizing radiation. Unlike x-ray, CDS was also able to detect various stages of NEC based on the type of...'Fickle' enzyme helps protect, but also can promote heart failure, animal study shows
...red by enzymes to function properly. "This study shows that nitric-oxide-making enzymes can have both beneficial and detrimental effects on the heart," says Kass. "However, the harmful effects can, at least in mice, be treated with its naturally occurring cofactor, BH4, suggesting a possible therapy in t...Substituting nurses for doctors results in high quality care, few savings
...by a nurse for less money." The evidence, however, shows that nurses' lower salaries do not necessarily equate to lower overall costs. The ANA advocates for removing regulatory and legislative barriers to increased use of nurses as health care providers. The systematic review included 16 studies totaling m......n.--A study of African-American women in menopause shows that while they experience many of the same symptoms as white women, they report more vasomotor symptoms such as dizziness and bloating, according to a study by a Yale School of Nursing researcher. The study included 43 African-American women in two...