Drug-eluting stent controversy explored in the American Heart Hospital Journal
...ances made possible by their use, and explores the significance of the benefits and disadvantages revealed through their high-volume adoption. Dr. Ulrich Sigwart of University Hospital in Geneva, Switzerland, author of one of the studies, examines the sobering current appraisal of DES use, in contrast to the t...Benefits of trastuzumab are lasting, reducing both HER2 + breast cancer deaths and recurrence
...s study clearly shows the statistical and clinical significance of the therapy, says Dr. Perez. The four-year data show a persistent benefit compared to what was seen at two years, according to Dr. Perez, with trastuzumab combined with chemotherapy continuing to outperform chemotherapy treatment alone. The firs...Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders
...lic acid deficiency. This outcome demonstrates the significance of the ability of the body to synthesize sialic acid for kidney development and function. NHGRI Clinical Director William Gahl, M.D., Ph.D., who was a co-author of the study, said, With respect to the disease HIBM, we are hoping that humans with t...Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes
... the Chinese University of Hong Kong, examined the significance of pre-chemotherapy HBV DNA levels in the blood on the survival of HCC patients. They studied 188 patients participating in a phase III randomized controlled trial comparing two different chemotherapy regimens. One hundred and seventy patients (92 p...High pretreatment PSA velocity predicts worse outcome
...gly suggests aggressive disease. Understanding its significance after treatment, particularly relative to other risk factors, is critical to identifying high-risk patients. Dr. Anthony DAmico of Bostons Brigham and Womens Hospital and co-investigators characterized PSA velocity significant in prostate cancer-sp...Bronchial thermoplasty may allow severe asthma patients to wean off oral corticosteroids
...nce. The study was not powered to show statistical significance in medication changes. In this group of patients with severe asthma, an increase in respiratory-related symptoms, and hospitalizations related to these symptoms, were expected and observed during the period immediately following the procedure. The...NY-Presbyterian Hospital/Columbia University Medical Center doctors present at 2007 AUA Meeting
... pathological techniques that may have altered the significance of positive surgical margins in prostate cancer. Thus, the researchers sought to determine if the predictive contribution of positive surgical margins on DFS has changed over the past 15 years. After performing an analysis of the Columbia Urologic On...UC environmental health chair recognized nationally for urologic research excellence
...pert in hormonal carcinogenesis, Ho focuses on the significance of hormones and endocrine disruptors in the development of breast, ovary, endometrial and prostate tumors. In the June 2006 edition of Cancer Research, she reported the first evidence of a direct link between chemical exposure while in the womb and p...The hepatitis C link: Diagnose, treat, transplant
...d by ANOVA, a statistical test that determines the significance of any given observation. Within purine metabolism, several genes were expressed between normal liver and both HCV groups. Of these, autotaxin was significantly elevated in patients with cancer compared to HCV patients without cancer or normal live...Statin use linked with decreased prostate cancer mortality rates, lower PSA levels
...tor that should be explored further to examine the significance that statin medications may have on prostate cancer detection. This abstract will be presented during Podium Session 16 on May 20 starting at 1:00 p.m. STATINS AND PROSTATE CANCER AMONG MEN PARTICIPATING IN THE FINNISH PROSTATE CANCER SCREENIN...Clinical guidelines for blood conservation during cardiac procedures developed
...sed at operation. Ferraris agreed with the great significance of the guidelines. "The blood conservation practice guidelines generated under the auspices of the Society of Thoracic Surgeons represents a landmark undertaking," he said. "This work should serve as a template for individual cardiothoracic surgeon...Food and drink, and what it says about us
..., increasing emphasis is being put on the cultural significance of the production, distribution and consumption of foodstuffs throughout all archaeological periods." The ancient Near East, the Mediterranean, Europe and the British Isles will all come under the postgraduates' microscope even the household diet ...Why predicting the next influenza pandemic is difficult and how scientists can best prepare
...lessons of past pandemics, the authors analyze the significance of the highly pathogenic avian influenza strain H5N1, which has spread among bird populations and infected hundreds of humans in the last decade. In preparing for the next influenza pandemic, however, the authors argue that researchers and public hea...Hepatitis C increases risk of non-Hodgkin lymphoma
...cancer was not increased. "Although the clinical significance of these findings is unknown, it is possible that screening of individuals infected with HCV could identify early stage lymphoproliferative conditions suitable for early intervention strategies, including chemoprevention trials on premalignant diseas...Health officials renew Indo-US Vaccine Action Program
...n of vaccine-preventable diseases of public health significance in India, the United States and other parts of the world, and to promote vaccines as one of the most cost-effective health technologies. National Institutes of Health (NIH) Director Elias A. Zerhouni, M.D., and Secretary of the Department of Biote...A frown or a smile? Children with autism can't discern
...part of the brain helps us discern the meaning and significance of what another person is thinking, Davies said. When responding to someone looking straight at you, as compared to someone whos looking away, the brain discerns a difference. When the other person looks away, the brain quiets down. For instance, ...Sleep deprivation can threaten competent decision-making
...f the brain involved with evaluating the emotional significance of an event. According to the authors, the new findings build on prior research that has shown that sleep-deprived participants choose higher-risk decks and exhibit reduced concern for negative consequences when performing a variant of the Iowa Ga...Higher calcium and vitamin D intakes positively associated with brain lesions in older men and women
...agues are continuing to investigate the effect and significance of high calcium and vitamin D intakes on brain lesions, including possible causality, in older patients with and without late-life depression. This research was funded by grants from the National Institute of Mental Health. MRI brain scans of a perso...Largest ever grant for University of Copenhagenhagen
...atory facilities to study human proteins and their significance for health and disease. "Thanks to this exceptional donation, we can boost research into what proteins look like and how they behave and interact in cells and tissues in healthy and sick people. This insight will provide entirely new opportunities ......Health to pursue a study to establish the clinical significance of diminutive polyps ( The need to define the natural history and biological significance of small polyps is central to refining colorectal cancer screening, irrespective of modality, says J...