Tag: "silence" at medical news

Researchers identify gene as protector of DNA, enemy of tumors

...ation. By using small interfering RNA (siRNA) to silence the BRIT1 gene, the scientists shut down both chec...ype of radiation. Researchers then used siRNA to silence the gene in normal human mammary epithelial cells (HMEC). The result: Inactivation of the gene cause...

Novel and pioneering research offers hope for cardiovascular disease

...d enzymes made of DNA, or DNAzymes, which find and silence the EGR-1 gene. He has used DNAzymes as unique tools to increase our fundamental understanding of the complex mechanisms of driving gene expression in vascular cells. "DNAzymes are essentially 'molecular assassins' that seek out specific genetic mate...

Tool developed to silence genes in specific tissues using RNAi

...developed a simple way to use the RNAi approach to silence a selected gene in a specific tissue in a mouse to... cells that ultimately become sperm. Using RNAi to silence WT1, therefore, led to the discovery that WT1 is the first transcription factor shown to regulate th...

US health care cuts are costing lives

...g record profits. She is committed to breaking the silence over these cuts and taking action. She calls on others around the world to join her in bringing national and international attention to human rights violations in the US....

Enzyme complex thought to promote cancer development can also help prevent it

...netic activity, and can work to either activate or silence gene expression. The M. D. Anderson researchers conclude that Akt regulates the ability of EZH2 to silence genes that are needed to protect against cancer development. When Akt is activated, it phosphorylate...

Nutrition gene key in regulating immune system

...d mice to eat a better diet also helps selectively silence the immune system, researchers have found. The finding may help explain how a mother avoids rejecting a genetically foreign fetus and provides a new target for treatments to help the immune system ignore other desirables like a transplanted organ. "...

Child sex abuse policy recommendations published in Science magazine

...od of memory failure. "Unfortunately, many factors silence victims of abuse," Freyd said. "Myths about the nature of child sexual abuse wrongly cloud the credibility of abuse victims in the eyes of the media and the public." Freyd and her former students, Anne DePrince and Kathy Becker-Blease, have investiga...

Used in a new way, RNA interference permanently silences key breast cancer gene

...r Research (AACR), used a modified form of RNAi to silence STAT3 in a permanent way. Typically, only a transi...ble to use RNAi in more than just experiments that silence genes temporarily," says the study's principal investigator, Ralph Arlinghaus, Ph.D., a professor an...

Louder neurons form more connections, Stanford research shows

...ce through another molecular twist. She managed to silence some neurons near the green, quietly-firing cells. When she did that, the green cells were able to compete successfully and formed longer, more complex arbors. Although this work specifically examined the brains of fish, Smith said the same rules lik...

Metabolic side effects of antipsychotics are known, but rarely monitored

...says. The newer class of drugs work effectively to silence the over-communication in the brain that causes hallucinations, the hallmark of schizophrenia, by dampening the action of the neurotransmitter dopamine. Somehow in that process of altering brain chemistry, they also make people hungrier and likely al...

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