Kidney cancer patients may be overtreated, U-M study finds
...ion called total nephrectomy. At the same time, by sparing the remainder of the affected kidney, patients may...h as diabetes or high blood pressure. In addition, sparing a portion of the affected kidney creates more options if a new tumor develops in the patient's secon...Preventing toxic side effects of inflammatory disease therapy
...fere with their roles in disease progression while sparing alpha4 functions required for normal health," said David M. Rose, D.V.M., Ph.D., assistant professor of medicine at UCSD, and co-author of the study. The research team created mutant mice known as "alpha4(Y991A) mice," in which the alpha4 integrin c...Fitness counteracts cognitive decline from hormone-replacement therapy
...ess levels also were associated with a significant sparing of the neural tissue of women not receiving hormone replacement therapy." Durations of therapy of less than 10 years showed enhanced tissue volume compared with all other groups, and the decline in tissue volume only began after 11 to 15 years of hor...International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy
...carries such an increased risk without evidence of sparing patients the known side effects associated with ART." The University of Minnesota's James Neaton, Ph.D., another principal investigator and chief biostatistician for the trial, notes, "The SMART trial reached a conclusion much earlier than we expect...Screening combination for PTs with colorectal cancer could reduce need for more invasive procedures
...duals who are less likely to have cancer, and thus sparing them the additional colonoscopic examination. 1486 participants who were guaiac FOBT positive were invited to participate, and around 50% returned samples for testing with the immunochemical test. Of these individuals, 173 (22%) tested negative in bo...Radiotherapy advance points way to noninvasive brain cancer treatment
... and penetrate them, down into their nuclei, while sparing the normal brain. Then, the patient's head is irradiated with x-rays. For these x-ray photons the whole brain is transparent, while gadolinium is opaque. Then, where gadolinium is localized-in the nuclei of the cancer cells only-what's known as "the ...Vitamin D status appears more important than high calcium intake for maintaining calcium metabolism
... values of serum PTH. Vitamin D may have a calcium sparing effect and as long as vitamin D status is ensured, calcium intake levels of more than 800 mg/d may be unnecessary for maintaining calcium metabolism. Vitamin D supplements are necessary to ensure adequate vitamin D status for most of the year in nort...Lung-sparing treatment for cancer proving effective
...on dosages, directing it all to the tumor site and sparing health surrounding tissue. The mapping allows physicians to administer higher doses of radiation while safeguarding uninvolved tissue and organs. Patients received three treatments in seven to 10 days versus standard therapy of 35 treatments over a...New radiation technique helps brain cancer patients keep their hair
...m and shape them to better target the cancer while sparing nearby healthy tissue (including hair follicles), allowing patients to significantly reduce the amount of hair they lost. Half of the patients in the study reported only slightly noticeable hair loss four weeks after treatment ended, and half had no ...Consensus panel calls for expanded role of needle biopsies, MRI and less invasive procedures
...se removal of the cancer is more likely, generally sparing patients a second surgery. A biopsy is for diagnosis, surgery is for treatment." The panel called the less invasive sentinel lymph node biopsy the "preferred method" for accurately staging image-detected breast cancer in mostpatients. The traditiona...Jefferson neurosurgeons, radiation oncologists wrap radiation around spine for cancer pain relief
...t the exact size and shape of the tumor all while sparing healthy tissue. It enables doctors to treat a range of hard-to-reach benign and malignant tumors in the brain and spine they couldn't treat before, often avoiding invasive surgery and speeding the patient's recovery. Neurosurgeon David Andrews, M.D....Cancer killing virus shows early promise against colorectal cancer
... These viruses selectively kill cancer cells while sparing normal tissue and are considered a promising new strategy to treat tumors. They have already been shown to be effective against chemotherapy-resistant cancers in preclinical studies. The specific strain of virus investigated by Prof. Kemeny's team wa...Tiny bundles seek and destroy breast cancer cells
...s targeted and destroyed only breast cancer cells, sparing the surrounding healthy tissue. Kester and his team first tested the ceramide-filled liposomes in a culture of breast cancer cells. The administration of ceramide reduced by more than 50 percent the number of breast cancer cells. Additional cell cult...Children need better cancer drugs, says expert panel
...ncers, but also cause fewer toxic side effects, by sparing healthy cells." The IOM report says that select components of a pediatric drug pipeline already exist in academic medical centers, industry, universities, and in federal centers such as the National Cancer Institute. Those resources include repositor...Presence of high-risk prostate cancer can be predicted without a biopsy, new study says
...ncer potentially may instead be closely monitored, sparing them the side effects of treatments." That's why researchers at the Oregon Health & Science University Cancer Institute and the Portland Veterans Affairs Medical Center (PVAMC) began searching for a way to predict which men have lethal prostate ...