Chromatin remodeling complex connected to DNA damage control
...hville, Texas. If DNA damage is like a fire that spreads when impaired cells divide and multiply, then the DNA checkpoint and repair system can be considered a first-response firebreak. Checkpoint genes temporarily halt a cell's division and assess its DNA. The "fire" is either doused by DNA repair or by p...Method shows promise for early detection of pancreatic cancer
...th no method of early detection, pancreatic cancer spreads rapidly and seldom is detected in its early stages. The new technique could lead to the first screening method for pancreatic cancer in asymptomatic patients, said Vadim Backman, developer of the technology and professor of biomedical engineering at ...U-M study finds lymphoma drug effective over long term
...t common type of non-Hodgkin's lymphoma. Lymphoma spreads easily through the lymph system and the bloodstream and consequently tends to be widespread when it is diagnosed. Traditional treatment often involves intensive chemotherapy, or a combination of chemotherapy and the monoclonal antibody rituximab. The...Ground breaking research to end in tears
...a small drop of oil into a bowl of water. The oil spreads overthe entire surface, so a little bit goes a long way. "When we looked closely at the thin surface layer of molecules on tears- the 'tear film' - we found proteins previously thought to be confinedto the aqueous portion of the tear," he says. F...The quest for an effective HIV vaccine presents new possibilities, challenges
...body, it infects crucial CD4+ T cells, replicates, spreads throughout the body and establishes HIV reservoirs in lymphatic tissues. Within weeks of exposure, virus levels peak and then decline to levels that may remain low for months or years. It is believed that CD8+ T cells--so-called killer T-cells--are r...Stenting of abdominal arteries offers welcome relief for 'intestinal angina'
...ked, gangrene develops in the bowel, and infection spreads throughout the body. More than half of such patients die, even with surgery. To evaluate the effectiveness of stenting for chronic mesenteric ischemia, Dr. Allie and his colleagues recruited 50 patients with a total of 74 areas of narrowing, or ste...Breakdown of myelin implicated in Alzheimer's, UCLA research shows
...mbers of axons with smaller axon diameters, and so spreads itself thinner and thinner, he said. As a result, it becomes more susceptible to the ravages of age in the form of environmental and genetic insults and slowly begins to break down. "The myelin breakdown process mimics the developmental process of...Weak immune response critical to disease that causes most infant hospitalizations
...pper respiratory infection. But in some babies, it spreads deep into the lungs, where it prompts coughing, wheezing and extreme difficulty in breathing, a clinical syndrome known as bronchiolitis. In these cases, the childs survival may require immediate medical attention. For the past four decades, medica...Sustainability of energy, food and water theme of ACS national meeting
...low-fever mosquito, and Anopheles stephensi, which spreads malaria. Callicarpenal and other compounds isolated from the plant also showed repellency against fire ants and ticks, says Charles Cantrell, a researcher with the USDA-ARS in University, Miss. (AGRO 199, Thursday, March 29, 10:30 a.m., McCormick Pl...Bird flu -- Call for antiviral drugs to be shared
... is low, it will take many months before the virus spreads w orldwide and there will be plenty of time to bring an effective vaccine into use. But if the number is high then it could be difficult or impossible to contain the virus with vaccination. Other measures could therefore be crucial, but it is like...Experts urge strongest isolation for new drug-resistant tuberculosis cases appearing in South Africa
...y an important role of containing XDR-TB before it spreads more generally in the population globally." "We would not argue for forcible treatment of MDR-TB or XDR-TB patients, simply restriction of mobility rights of such individuals," the authors say, adding that detained patients need appropriate legal co...New amfAR research grants aim to advance understanding and prevention of rectal HIV transmission
...Understanding the extent to which anal intercourse spreads HIV infection will become increasingly important as researchers race to devise microbicides, which may be effective only when used vaginally. Findings made by these new amfAR researchers will contribute to the development of prevention technologies t...In case of pandemic flu majority of Americans willing to make major changes in their lives
...irst read a scenario about an outbreak of flu that spreads rapidly among humans and causes severe illness. They were then asked how they would respond to and be affected by the circumstances that would arise from such an outbreak. Willingness to Cooperate with Public Health RecommendationsMore than three-...Researchers use novel three-dimensional imaging technique
...A researchers have tracked how Alzheimer's disease spreads through the hippocampus -- the area of the brain linked with memory -- in a pattern consistent with the known trajectory of neurofibrilliary tangle dissemination, an accumulation of diseased proteins in the brain cells. They found that three areas wi...New prostate cancer marker helps identify men whose cancer is likely to spread
...e-threatening metastatic disease where the cancer spreads to other parts of the body such as the bones. This new marker can identify which men are at the highest risk of metastatic disease at the time of their initial surgery leading to tailored treatment for individual prostate cancer sufferers, something ...Resistant bacteria increasing source of muscle infection
...The form of MRSA that is acquired in the community spreads more easily than that usually caught in the hospit... find out why this particular form of the bacteria spreads so easily. Her studies are focusing on specific genes. One, pvl, permits holes to be poked into the ...Newly discovered behavior in cancer cells signals dangerous metastasis
...a new understanding of how cancer metastasizes, or spreads to other parts of the body, said the Duke Comprehensive Cancer Center researchers who conducted the study. "Understanding this toggle switch might ultimately enable scientists to find ways to stop cells from metastasizing, which is the most deadly t...A public health lesson from 9/11: To curb the flu, limit flights
...een able to show, using real data, that air travel spreads the flu, suggesting that reducing the number of air passengers might ameliorate a flu pandemic." The spread of avian flu (H5N1) in Asia and Europe, including some likely cases of person-to-person transmission, has intensified debate over whether f...Air travel and flu: Post-9/11 restrictions delayed start of season
... flu', it is important to know more about how flu spreads round the world. Might airline travel play a role in the spread of the infection across large distances? If so, reducing or restricting air travel might be useful in the early stages of a serious global epidemic. Research at the Children's Hospital B...Thirty percent of nurses report both verbal and physical abuse in the last four working weeks
...his research was that although verbal and physical spreads across every branch of healthcare from paediatrics to psychiatry and community services to critical care few staff made their complaints official." Workplace aggression is a world-wide problem and further research is needed to discover why level...