New microfluidic devices found to be effective method of in-vitro fertilization in mice
... than the culture dish," he says. During the early stages of the study, researchers found that, contrary to their initial hypothesis, a much lower fertilization rate was achieved with the microfluidic device (12 percent) than in culture dishes (43 percent). They then hypothesized that as sperm concentration...Proteome Systems signs agreement with Prince Henry's Institute for Ovarian Cancer Diagnostic Test
...identification of diagnostic markers for the early stages of ovarian cancer will provide the basis for the development of a screening test and lead to a better prognosis for women with this disease. Women would be able to regularly screen for ovarian cancer as is currently possible for breast and cervical ...Elevated blood levels of a protein are linked to asbestos-induced cancers
...rsity have found a molecule that reveals the early stages of pleural mesothelioma, a chest cancer caused by ...for this type of cancer, particularly in its early stages when treatment may be more successful. The blood test could help to monitor people at risk of develo...Cervical cancer has profound psychosocial impact on affected women, as well as male partners
... couples in which the woman had cervical cancer at stages 1-4, up to two years post-treatment. The couples were asked questions about the impact of the disease and treatment as well as general psychosocial impact. Their predominant concerns included prognosis, communication with the treatment team, and as...American Thoracic Society Journal news tips for October 2005 (second issue)
...ents who have pulmonary embolism into five disease stages that show increasing risk of death or other adverse outcome. To develop and test the rule, the investigators studied data from 15,531 discharged patients who had been hospitalized for pulmonary embolism at 186 Pennsylvania hospitals. For the study, ...Annals of Internal Medicine tip sheet for Oct. 18, 2005
...provide much-needed options for treating the later stages of diabetes (Editorial, p. 609). However, until development of "precise molecular targets" for type 2 diabetes, lifestyle choices (increasing exercise and reducing weight) will be the cornerstone of managing this debilitating and increasingly common ...Antipsychotic drugs linked to increased risk of death for some elderly Alzheimer's patients
...rug reactions could be more prominent in the early stages of a course of medication treatment. He noted the possibility that higher death and illness rates might exist among frail individuals exposed to other classes of drugs, but the absence of long-term data limits the ability to study this question. "We ...In a crisis, creating DNA vaccine could help save lives, slow spread of 'bird flu'
...mals. However, human trials are still in the early stages so the safety and efficacy of these vaccines isn't fully established in people. But these trials could be accelerated, Dunnill says, particularly if the H5N1virus eventually causes large numbers of human deaths and out paces the supply of conventiona...Stanford study reveals protein's Jekyll-and-Hyde role in cancer growth
...onstructively, helping guide cells through all the stages of development from their beginnings as blood-forming stem cells to final maturation, or differentiation, into blood cells. But when MLL is mutated, the differentiation process stalls at an intermediate stage and the immature cells begin proliferatin...Molecular studies in cancer of the colon
...gh hopes for positive results concerning the early stages in the development of this illness. This can open the doors to an early diagnosis and, thus, to efficacious treatment. Biological treatments are the basis of the new strategy in cancer therapy. In fact, one of the aims of CIMA is directed to looking ...Doctors call for urgent review of cancer initiative
...diagnose and treat cancer earlier is to target all stages of the process, including patient education, screening, investigations and treatment." Mr Hanna and his colleagues have urged the Government to rethink their cancer target after they reviewed the results of 35 UK cancer studies carried out since th...Decline in breast cancer deaths explained by use of screening and adjuvant therapies
...be more effective if cancer is detected at earlier stages by screening." Berry stresses that the differences in conclusions reflect uncertainties in the interpretation of available information and differing modeling approaches, rather than contradictions among the models. "These are seven top modeling grou...New clues into causes of scleroderma
...iments in mice that they are in the early planning stages of a clinical trial incorporating their findings in human patients with the disease. Scleroderma is a chronic degenerative disease that afflicts more than 300,000 Americans, primarily women. The life-threatening disorder is marked by dramatic tissue ...Headlines about Herceptin show equality of access to costly drugs must be tackled
...astuzumab) for treating breast cancer in its early stages shows that issues of equal access to costly but effective drugs must be confronted, says an editorial in this week's BMJ. Trastuzumab was "rapidly adopted as the standard of care" in the US for treating breast cancer, but one of the barriers to its ...Developmental Origins of Health & Disease conducts third international congress
...s the notion that events occurring in the earliest stages of human development even before birth may influence the occurrence of major conditions, such as diabetes, cardiovascular disease, asthma, cancers osteoporosis and mental disorders. The Third International Congress of the Developmental Origins of ...Race can affect decision about lung cancer treatment
...s and whites were offered and accepted surgery for stages I and II non-small cell lung cancer. Of the 97 blacks and 184 whites in the study, 74 percent of whites underwent surgical resection, compared with 58 percent of blacks. Within the two groups, 79 percent of whites was offered surgery, compared with 7...New malaria vaccine shows promise in early clinical trial
...r, this risky test is not ethical during the early stages of vaccine testing. But Druilhe and colleagues were nevertheless able to take their early trial a step further: They demonstrated that antibodies from the blood of vaccinated volunteers were able to inhibit growth of the malaria parasite in two ind...Backyard treatment may yield leukemia treatment
...-versed in the signs and symptoms of the different stages of CML, but until now, they have had few clues about what actually causes the disease to progress. Perrotti said his studies show that it may be due to the increased activity of Bcr-Abl itself. Through extensive chemical and genetic tests conducted...New antibody profiling technique to test for lung cancer
...ant disease, differentiating histologies, defining stages and responses to therapy, and defining prognosis. "These goals have generated considerable interest in identifying predictive tumor markers," Dr. Zong continues. "Although a number of non-small cell lung cancer tumor markers are measurable and a c...Research reveals likely connection between early-life stress and teenage mental health problems
...r mothers removed from the social group at various stages early in life. These monkeys continued to be raised in the stable social groups with other monkeys similar to a human child that loses a parent but continues to be raised in their family. Some infant monkeys had their mothers removed from the social...