2005 Potamkin Prize goes to neurologists for research in early detection of Alzheimer's disease
...Growdon said, "Dr. Petersen's Potamkin recognition stems from his seminal contributions in establishing the concept of mild cognitive impairment as a bona fide diagnostic category on the continuum between normal aging and early dementia. The impact of MCI has been enormous, and has transformed clinical and...Infants with rare genetic disease saved by cord blood stem cells
... fatal "lysosomal storage diseases," each of which stems from a specific enzyme deficiency. These disorders include more than 45 rare diseases, such as Krabbe Disease, Hurler Syndrome, Adrenoleukodystrophy, Metachromatic Leukodystrophy, Tay-Sachs disease, Sandhoff disease and a host of others. "The diseas...Teenage depression can be enduring, but is more often short-lived
...luding this one: "A lot of people think depression stems from a weakness in character, and that you should just keep a stiff upper lip," Hammen said. "It's a myth. People cannot simply will depression away. It can be a serious impairment, and may require treatment. It's not a weakness of will."...Japanese doctors likelier than US counterparts to involve patients' families in decisions
...l become depressed or give up home. Another reason stems from the long tradition of family decision making in Japan. Frequently, a family caregiver is informed by the physician of a patient's cancer diagnosis, treatment plan, and prognosis before the patient is told the truth. After discussions with othe...Funding for biomedical research doubles in last decade
... believe a major factor in decreasing productivity stems from pharmaceutical companies' frequent determination that compounds approvable from a regulatory standpoint are not worth bringing to the market because the intensity of competition is so high that it is not worth challenging existing drugs that are...No reason to fear very low LDL
...ents with very high doses of potent statins. This stems largely from the epidemiologic literature which shows that patients with very low cholesterol, not on treatment, have higher mortality," Dr. Wiviott said. There was no significant difference in safety outcomes among the groups of patients, including ...Major EU grant to develop cancer-fighting cells
... large numbers back into the patient. The approach stems from original research by Professor Zelig Eshhar in Israel, and the partners include experts in immunology and tumour biology as well as those who have developed key aspects of engineered T-cells. Professor Hawkins continued: "Already vaccines can ...Government plans for NHS more aggressive than Tories ever were
...e author. The escalating use of the private sector stems from the NHS Plan in 2000, when the Government pledged to reduce waiting times, but realised that the NHS was too short of doctors and facilities. The NHS already paid for extra capacity from private healthcare on an ad hoc basis, usually to meet yea...... Heart Failure: Evidence for a Pediatric Syndrome" stems from a collaboration between the Renal and Cardiology departments. While adults frequently develop acute renal failure (ARF) during episodes of acute decompensated heart failure (ADHF), data has lacked for children. The research done by Dr. Goldstein...Hair follicle stem cells contribute to wound healing
...ins of the new cells-specifically, what percentage stems from the deep follicle and what percentage from the epidermis near the wound. Cotsarelis' team found that adult stem cells from the lowest portion of the hair follicle, or "bulge," quickly ascend the follicle in response to wounding and ultimately c...UCLA finds cancer drug may improve progeria; genetic disease causes accelerated aging in children
...inson-Gilford Progeria Syndrome (HGPS or progeria) stems from a mutation that leads to the accumulation of an abnormal protein on the scaffolding of the cell nucleus. The abnormal protein causes misshapen cell nuclei and ultimately leads to all of the disease findings of progeria. In earlier studies, th...Chocolate milk could be key to longer, healthier life
...bility of people to create energy and perform work stems from structures that exist inside our cells called mitochondria. As we grow older the amount of mitochondria we have decreases and with it our respiratory capacity. "This decline is determined by the turnover of proteins in the mitochondria. We hope...Keeping patients from falling through the medical-imaging cracks
...is just one example of a patient-safety issue that stems from inadequate communication, incomplete handoffs between professionals and systemic "holes" that patients can slip through, Marn adds. The researchers also collected data on patients with "Code 4" tags on their medical images, meaning that the rad...Uncertainty over give antibiotics in exacerbations of COPD
...d to combat exacerbations of COPD. The uncertainty stems from the growing desire to use antibiotics only when necessary, combined with the recognition that up to one third of exacerbations of COPD have are not caused by infections, and some others are due to viral infections. A large number of trials have ...New compound unusually potent at blocking brain cancer growth
...icult to treat. The unique effectiveness of PI-103 stems from its ability to attack two separate steps in the series of signals that trigger the spread of cancer. The dual blockade proved to be a safe and effective inhibitor of cancer cell proliferation in mice with the human tumors, the scientists found. ...Reconstructing a healthcare system in Iraq
...ssion. Malnutrition was also a serious concern. It stems from both prolonged political sanctions in the region and mismanagement that impeded the success of the United Nations' oil-for-food program in the country during the 1990s. "The feedback provided by the nurses in this study demonstrates clear priori...Some patients with heart attack shock survive years after aggressive treatment
... The latest report from Dr. Hochman's group stems from an international trial funded by the National Heart, Lung, and Blood Institute called SHOCK, which enrolled 302 patients between 1993 and 1998 at 29 tertiary care centers. All patients were initially treated with medications and IABP to support...Aspirin and other NSAIDs may not reduce the risk of colorectal cancer in long-term smokers
...nt NSAID use." The link between smoking and cancer stems from the fact that cigarette smoke contains hundreds of carcinogenic metabolic products that may damage DNA. "This accumulated damage might not be reversible," Chia said. "NSAIDs act to suppress inflammatory processes and may help limit the progressi...Chronic middle ear infections linked to resistant biofilm bacteria
... It appears that in many cases recurrent disease stems not from re-infection as was previously thought and which forms the basis for conventional treatment, but from a persistent biofilm," Ehrlich said. "Given that bacteria living in biofilms are metabolically resistant to antibiotics, this study make......f off-label prescribing for antidepressants likely stems from the high degree of overlap in symptoms among various mental illnesses. The high rates of off-label prescribing of powerful antipsychotic and anticonvulsant drugs for the elderly underscores the lack of effective treatments for Alzheimer's diseas...