Drug-eluting and absorbable stents push interventional frontiers
...ed to long-term mechanical stress, for example, or stimulate a biological interaction with the artery wall. Future catheter procedures would be simplified. Equally as important, noninvasive imaging of the treated artery would also be possible with these stents. Currently, patients with permanent metal stents...Research mice help scientists understand the complexities of cholesterol
...rapies. Several drugs have been developed that can stimulate the ABCA1 gene to produce good cholesterol, but they aren't useable in humans because of negative side effects. The scientists hope to learn more about how the drugs work and how they could be improved. "The animals can help us determine which pathwa...Protein sorting in pigment cells sheds light on melanoma, Alzheimer's disease
...nce in melanoma patients that via Pmel17 you can stimulate helper T cells, whose antigens are also processed ...ss to dendritic cells and perhaps their ability to stimulate T cells."...Clarifying controversy in multiple sclerosis
...duction of an anti-inflammatory protein IL-4 could stimulate MGs to support nerve cell survival. In contrast, ...ses of IFN-gamma, because high levels of IFN-gamma stimulate the MGs to produce TNF-alpha. The results demonstrate that the helper T cells can have direct contr...Melanoma vaccine strategy shows promise in laboratory experiments
... percent of melanomas, but not in normal cells, to stimulate immune cells called killer T cells to attack the melanoma cells. Another type of immune cell called a monocyte was used to present the peptide, BRAFV600E, to the killer T cells to trigger their attack on the melanoma cells. "In our experiments, we sa...NIH holds state-of-the-science conference: Caesarean Delivery on Maternal Request, March 27-29, 2006
...D) and OMAR have planned the upcoming conferenceto stimulate a critical review of the available evidence and to identifydirections for future research....Bird-flu vaccine works at high doses; Focus turns to ways to stretch vaccine supply
...reason, the H5N1 strain of avian flu just does not stimulate the immune system as much as the regular flu does," Treanor said. Currently Treanor's Rochester team is involved in five studies to learn more about bird flu and test a vaccine against it: Rochester is one of four sites of a study of 240 people tes...Research suggests that immune response protects against brain tumor development
...r Center have found that allergies and asthma that stimulate inflammation may be protective, but use of antihistamines to control the inflammation could eliminate that protection. In this study, reported at the annual meeting of the American Association for Cancer Research (AACR), the researchers also associat...COX-2 inhibitors significantly reduce risk of cancer
...tant in cancer because when it's activated, it can stimulate many key steps in cancer development, including cell division, inhibition of cell death, angiogenesis (the creation of new blood vessels to nourish growing tumors) and metastasis," says Harris, who is also a member of the OSU Comprehensive Cancer Cen...Researchers find why prostate drug increases likelihood of heart failure
...e a drug that specifically activates them? Can you stimulate them to cause the heart muscle cell to recover when it's injured, or grow stronger when it's weak?" Simpson points to a history of research work going back to 1982 that has indicated the potential beneficial effects of alpha 1 receptor stimulators. "...The $6 billion (hu)man is becoming reality, as bionics restores or expands humans' abilities
...ts with degenerative retinal diseases which is to stimulate the cells in the retina to perceive images. When tested in rats, the retinal neurons migrate into the porous interface with the subretinal implant and thus provide intimate proximity between the stimulation sites and the neural cells, which is essen...Factor stimulates cartilage growth from stem cells
...o a cocktail of various growth factors in order to stimulate their transformation into cartilage cells. The gro...ment of mesenchymal stem cells with BMP-6 tends to stimulate the transformation into bone cells, the treatment of hADAS cells with BMP-6 stimulates cartilage cel...Assessment model gauges lung cancer risk based on medical history and genetics
... poor DNA repair genes. Allergies are believed to stimulate an immune response in lungs that help fight initial tumor development, Schabath says. The model is a work in progress, says senior author Margaret Spitz, M.D., professor and chair of the Department of Epidemiology. "It appears to be reasonably accura...ISHLT celebrates 20th anniversary of infant cardiac transplantation
...risk for complications from CMV, this study should stimulate further research into the role of CMV in coronary artery disease. Another significant study showed that routine bronchoscopy a visual examination of the lungs through a lighted, flexible tube in pediatric lung transplant recipients during the firs...Stem cell transplants improve recovery in animal models for stroke, cerebral palsy
... by producing factors that limit tissue damage and stimulate repair, according to Dr. Gil Van Bokkelen, the company's chairman and chief executive officer. In addition, MultiStem TM cells can safely mature into a broad range of cell types and can be produced on a large scale, something which should ease the ...New research links metabolism and appetite suppression, opening door to obesity treatments
...resence of proteins which inhibit their ability to stimulate fat metabolism," says Dr. Steinberg, a Canadian researcher at the University of Melbourne, Australia. "Fortunately, CNTF's effects on fat burning are maintained." Nearly half of all adult Canadians are overweight or obese and 26 per cent of Canadian...Innovations in the care of women during pregnancy and labor
...s guest editor Moos. "I am hopeful that they will stimulate you to examine the current and potential energy in your practice setting to encourage family-centered maternity care" In the first article Prenatal Care: Limitations and Opportunities, Moos, explores the limitations of the way pregnant women are curr...American Academy of Neurology 58th Annual Meeting scientific highlights
...tentially significant. Antisense oligonucleotides stimulate the body's own cells to destroy selected genetic messages before they can become harmful. Researchers who used antisense oligonucleotides against SOD1 showed they could treat wide areas of the brain in both rats and monkeys, decreasing SOD1 and incre...Latest issue of Alzheimer's & Dementia explores new ideas for cause, screening and risk factors
...iation continues to feature valuable new data, and stimulate thought and discussion with provocative perspectives on key issues, such as alternative theories for the cause of Alzheimer's. Included in the journal's April 2006 issue are:Screening - A call for consideration of dementia risk factors in individuals......of the JAK kinases. The activated JAK kinases then stimulate cell growth through a signaling pathway that operates alongside the one controlled by the Bcr-Abl kinase, Sherr said. Therefore, the St. Jude investigators used a chemical inhibitor of JAK kinases to block the effect of IL-7 on leukemic cells in cult...