Penn study finds pro-death proteins required to regulate healthy immune function
...gnaling problems, increases energy production, and stimulates cell division. The results, published online in the journal Immunity, bolster the teams hypothesis that metabolic cell activity directly controls life and death decisions in cells. This issue also includes a related commentary by the studys lead a...Trials underway for 'essential' new TB vaccine
...duced with a vaccine. "This vaccine is safe and stimulates very high levels of the type of immune response we think we need to protect against TB. It is important for us to test whether or not this vaccine does work to stop people getting TB," says Dr McShane. Following successful safety trials in The Gamb...Low-carb diets' effects linked to rise in newly identified 'starvation hormone'
...iver in response to fasting in mice. FGF21 in turn stimulates lipid breakdown in white adipose tissue and ketone body production in the liver. They unexpectedly also found that FGF21 led the animals to reduce their physical activity and made them more sensitive to entering torpor, a short-term, hibernation-like...Brain-boosting pill alleviates post-chemotherapy fogginess
...w options. Some studies have tested Ritalin, which stimulates the central nervous system. But Ritalin has unwanted side effects like headaches, irritability and addiction, Kohli said. Since modafinil does not linger in the body, side effects are minimal, according to recent studies. Initially, researchers loo...Phase II study shows combination improves survival of metastatic melanoma patients
...), a substance naturally produced in the body that stimulates the formation of new blood vessels, a process known as angiogenesis. This process is essential for tissue repair, such as wound healing, and for the overall the health of the body. VEGF is also important for tumor growth, which depends to a large e...'Smart' mice teach scientists about learning process, brain disorders
...d NR2B, which is found in nerve-cell membranes and stimulates the cell to fire when a nerve-cell-signaling molecule, or neurotransmitter, binds to it. NR2B previously has been implicated in the early stages of learning. The new research showed that when Cdk5 is removed from the brain, the levels of NR2B signi...Nanomedicine opens the way for nerve cell regeneration
...NPs) may be used to create mechanical tension that stimulates the growth and elongation of axons of the central nervous system neurons. The second method from the University of California, Berkeley uses aligned nanofibers containing one or more growth factors to provide a bioactive matrix where nerve cells can ...Alternative hormone treatment could help fight against breast cancer
...ing hormone is produced in the pituitary gland and stimulates ovulation and the production of oestrogen. LHRH agonists are molecules which mimic the action of luteinising Hormone by binding to the same receptors within the pituitary gland and thereby block the signal for ovarian production of oestrogen, which i...Some children are born with 'temporary deafness' and do not require cochlear implant
...c device that bypasses the hair cells and directly stimulates the auditory nerve. Prof. Attias stresses that a cochlear implant is an excellent treatment for children with congenital deafness whose hearing does not improve over time. However, it appears that some children are born with "temporary deafness" a c...Effectiveness of first renin inhibitor drug for treating hypertension is limited
...ed by less than 50% of patients. Because aliskiren stimulates kidney renin secretion to a greater degree than do CEIs or ARBs, its antihypertensive capabilities can be counteracted by large reactive increases in renin secretion; this is particularly likely at higher dosage. Writing in the article, Jean E. Sea...New, less painful wound treatment for pediatric patients
..., provides a closed, moist healing environment and stimulates the formation of granulation tissue, an important indicator of healing tissue." Ninety-three percent of the children given the treatment showed decreased wound volume, and the average amount of wound closure was 80 percent. "This is very good news ...Researchers urge caution in using ESAs for cancer-related anemia
...ed forms of a protein called erythropoietin, which stimulates red blood cell production. The drugs are widely used to treat anemia: low levels of hemoglobin, the oxygen-carrying protein in the blood. They are approved for use in treating anemia in patients with chronic kidney disease and in cancer patients with...New animal study may explain why alcohol consumption increases breast cancer risk
...t animal model to confirm that alcohol consumption stimulates tumor growth and malignancy of breast cancer, and ...at even moderate alcohol consumption significantly stimulates tumor growth of breast cancer and that induction of tumor angiogenesis and VEGF expressions are mech...Diet and lifestyle -- In the cancer fight, eating well is the best revenge
...s of the CXCL12 chemokine ligand. This attraction stimulates the invasive properties of cancer cells and acts like a homing device, drawing the cancer cells to the organs they metastasize to. When breast and ovarian cancer cell lines are exposed to purified DIM or genistein, levels of CXCR4 and CXCL12 messe...Schmalz to receive major IADR Pulp Biology Research Award
... and plaque. The award recognizes, encourages, and stimulates outstanding research contributions in the field of pulp biology and is one of the Distinguished Scientist Awards conferred annually by the IADR, representing the highest honor the Association can bestow. ...International and American Associations for Dental Research present awards and fellowships
...tablished by the Borrow Foundation, recognizes and stimulates research in oral health prevention for children, with a priority for caries prevention using fluoride in different formats. This is the 16th year of the Borrow Award, which consists of a cash prize and a plaque. The IADR David B. Scott Fellowship ...Cancer drug can extend survival in patients with deadly brain tumors
...vascular endothelial growth factor, a protein that stimulates development of new blood vessels in a process known as angiogenesis. New blood vessels spur a tumors growth and ability to spread, so researchers are interested in cutting off angiogenesis to slow tumors down. Avastin is an anti-angiogenesis drug tha...Low-pitch treatment alleviates ringing sound of tinnitus
...ant replaces the damaged mechanism in the ear that stimulates the auditory nerve, Zeng believes that a properly pitched acoustic sound will have the same effect on tinnitus for someone who does not use a hearing device. Dr. Hamid Djalilian, a UCI physician who treats hearing disorders, points out that a custom ...Hormone drug type makes survival difference in advanced breast cancer
...ogical therapies. In many breast cancers, estrogen stimulates tumor growth. Aromatase inhibitors work by limiting a woman's production of estrogen. Several aromatase inhibitors, including anastrozole (Arimidex), exemestane (Aromasin) and letrozole (Femara) have been available for clinical use for the past de......old as Amaryl), another type of diabetes drug that stimulates the pancreas to make more insulin. Patients received a baseline ultrasound to measure the thickness of the lining and middle layers of the carotid arteries, which carry blood to the brain. The arteries' thickness is a marker for coronary atheroscler...