American Thoracic Society Journal news tips for April 2005 (first issue)
... soon many patients developed antibiotic resistant strains and little ultimate benefit came to those treated.... Great Britain showed that almost all tuberculosis strains had primary resistance to only one drug. Treatment with a 2- to 3-month three-drug phase, followed ...Angiogenesis factor may help tumors prepare the way for spread to lymph nodes
...than did mice with normal VEGF-A expression. Both strains of mice had increased levels of angiogenesis associated with benign and malignant tumors, but the transgenic mice also had more and larger lymphatic vessels than did the normal mice. In addition, the new lymphatic vessels were shown to carry the rece...Will cancer vaccine get to all women?
...November 2004 that its vaccine, which contains two strains of HPV thought to cause 70 per cent of cervical ca...ne, which contains the same two cancer-causing HPV strains plus two strains that cause genital warts. Merck's official reason for including the warts strains...Football is a pain in the neck
...s and dislocations and lacerations to concussions, strains and sprains. Overall, researchers discovered those playing football suffered significantly more neck injuries, than those playing hockey or soccer. Sport Overall neck injuries Football 5.85 Hockey 2.8 Soccer 1.67 (expresse...New insights into HIV immunity suggest alternative approach to vaccines
...ng antibodies those antibodies that kill most HIV strains are made. This provides a plausible explanation f...-specific antibodies that can kill all or most HIV strains with a similar vaccine design. Some broadly neutralizing antibodies have been isolated from HIV-inf...Milk thistle does not reduce deaths from liver diseases, best studies find
...irus can be cleared in a handful of patients, many strains are resistant to treatment. Drug therapies that focus on long-term suppression of the virus are expensive, and many patients develop a resistance. The current gold standard treatment, which combines injections of interferon and ribavirin, has seriou...Two studies offer clues about how alcoholic behavior is 'switched' on
...increased the number of dopamine "D2" receptors in strains of mice with genetically varying levels of D2 receptors. Earlier Brookhaven studies have shown that "up-regulating" D2 receptors by delivering the D2 gene directly to the brain's reward center decreased drinking behavior in rats trained (see: http:/...Leprosy genome tells story of human migrations, French researchers report in Science
...e in French . A French genetics study comparing strains of leprosy-causing bacteria has revealed some surp...enome and the subtle differences among its various strains worldwide, the better position we'll be in to ultimately eliminate the disease," said Caroline Ash, ...Sabin Gold Medal awarded to vaccine developer Dr. Albert Z. Kapikian
...ting outer proteins from different human rotavirus strains with a monkey rotavirus that is attenuated (weaken...rotective against the four most important clinical strains of rotavirus. In 1998, this vaccine became the first rotavirus vaccine licensed in the United States...'Sister Mary' the robo-doc to start making ward rounds at St Mary's Hospital
...o get to them. "If we look at a lot of the current strains on the NHS many senior doctors with skills and knowledge are required to be in several places at once. This is a solution in potentially providing their expertise from a remote location and may be a significant step for patient care." The robots are ...African HIV subtypes identified in Minnesota population
...rent subtypes were identified, all consistent with strains endemic to the patients' regions of birth. Of the non-African HIV-1-infected patients, 25 were successfully subtyped and all were infected with subtype B. The researchers believe that their results underestimate the prevalence of non-B subtypes in Mi...Delirium in non-ventilated patients predictor of longer hospital stay
...itating after- effects in patients and unnecessary strains on hospital resources....Skin infections caused by MRSA are cured more often when treated with Pfizer's ZYVOX
... of the following infections caused by susceptible strains of the designated microorganisms: Complicated sk...tococcus pneumoniae (including multidrug-resistant strains [MDRSP]*). Combination therapy may be clinically indicated if the documented or presumptive pathoge...Variant prion protein causes infection but no symptoms
...exposed two groups of 6-week-old mice to different strains of the agent that causes scrapie, a brain-wasting disease of sheep. Within 150 days of being inoculated with the natural form of scrapie prion protein, all 70 mice in the control group showed visible signs of infection: twitching, emaciation and poor...Chest x-rays not effective in determining when TB acquired
...morphism (RFLP) analysis is a method for comparing strains of MTB from individual patients on a genetic basis. These techniques allow comparison of patients who have recently acquired tuberculosis to those whose tuberculosis was acquired long ago. The researchers in this study used molecular fingerprinting...Multi-drug resistant TB persists in California
... number of cases. Additionally, cases of TB due to strains of Mycobacterium tuberculosis that are at least re... appeared for any of 3 reasons: importation of MDR strains from outside the state, endogenous development of MDR strains due to inadequate case management or p...Johns Hopkins team finds 'ancestral' hepatitis-C virus at the root of evolution in infections
...arison of genetic changes across multiple genes in strains from chronically infected people to the original s... mutates, or alters its genome, very rapidly. Its strains have two to three times more genetic variability, for example, than HIV, the virus that causes AIDS,...A virus-like hitchhiker may trigger bacterial meningitis
...y tract, usually without consequence. But certain strains of N. meningitidis -- known as 'hyperinvasive' strains -- occasionally find their way into the blood stream and then into the brain, where they trigger a p...Johns Hopkins scientists uncover clues to 'disappearing' precancers
...nd more than half of these women are infected with strains of the virus that could likely turn a precancerous...h HPV and up to three-quarters of these have viral strains that are linked to cervical, oral and anal cancers. More than 10,000 cases of cervical cancer are di......uly 11, demonstrates how curcumin stops laboratory strains of melanoma from proliferating and pushes the cancer cells to commit suicide. It does this, researchers say, by shutting down nuclear factor-kappa B (NF-kB), a powerful protein known to promote an abnormal inflammatory response that leads to a variet...