Tag: "suppresses" at medical news

'Supersize me' mice research offers grim warning for America's fast food consumers

...s there's evidence that suggests fructose actually suppresses your fullness, unlike fiber-rich foods, which make you feel full quickly. The take-home message for humans is obvious, he says. "A high-fat and sugar-sweetened diet compounded by a sedentary lifestyle will have severe repercussions for your liver...

Ireland Cancer Center researcher lays out benefits of aspirin to prevent colon cancer

...on the findings of a new "Celebrex-like" gene that suppresses the grown of colon cancer in the July 2006 issue of Proceedings of the National Academy of Sciences. Dr. Markowitz likens the gene, called 15-PGDH, to a naturally occurring Cox-2 inhibitor such as Celebrex. These findings may lead to the developmen...

Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment

...a, breaks down lipids surrounding CFTR and thereby suppresses CFTRs chloride-passing function. To make matters worse, the products of the lipid breakdown are also known to trigger inflammation and cell death. Together, these facts compellingly suggest that SMase plays a critical role in the heretofore myster...

Smoking increases risk of TB infection, says new study

...ne of the most important. It could be that smoking suppresses the respiratory immune system, allowing latent infections to blossom. Smoking also seems to make people more susceptible to becoming infected in the first place." In 2003, 8.8 million people worldwide developed active tuberculosis, and each year, a...

Natural, soy-based substance might help fight MS, Jefferson neuroscientists find

...s in multiple sclerosis, but they theorize that it suppresses the immune response to some extent, in addition to inhibiting proteases. Dr. Rostami sees BBIC as being used as a single therapy or in conjunction with other drugs in treating MS. He notes that because current therapies for MS involve injecting drugs...

Drug combination slows progression of treatment resistant bone marrow cancer

...use it affects white blood cells, multiple myeloma suppresses the immune system, so patients can develop sometimes-fatal infections. Other complications include kidney failure, bone pain, anemia, and bleeding. Doxil is a liposmal version of an older drug, doxorubicin, which means the drug is encapsulated in a...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

... with Freund's complete adjuvant, a substance that suppresses the activity of the immune cells that destroy islets in type 1 diabetes. They also introduced donor spleen cells to retrain the immune system not to attack islets and found that the protocol not only halted the immune destruction caused by diabetes ...

Sticky proteins provide new insight into drug action

... at all clear how the cell allows one response and suppresses the other. That likely is because the G proteins activated by epinephrine receptors don't readily dissociate, contrary to the textbook picture. MCG researchers have also shown that at least one other class of G proteins does dissociate, suggesting ...

Two-faced protein can stop metastasis or promote it, researchers say

...t promote cell movement. "We show that E-cadherin suppresses invasion, at least in part, by binding to p120 protein in the cell," Anastasiadis says. "If E-cadherin is missing, p120 is free to bind to mesenchymal cadherins, setting off a process that leads to metastasis." Thus, p120 acts as a "rheostat" that p...

New drug target might sidestep gleevec resistance, Jefferson scientists show

...amoxifen, this chimeric protein is switched on and suppresses tumorigenesis." They also were able to halt leukemia in cells resistant to Gleevec. They established a leukemia cell line that expressed a Gleevec-resistant mutation, reactivated the CEBP-alpha, and stopped leukemia development. Could Gleevec be ...

Scientist-astronaut sends T-cells into space

...arget of human immunodeficiency virus (HIV), which suppresses them. When an HIV patient's T-cell count falls below 200, he or she is susceptible to the dangerous infections that are the symptoms of acquired immunodeficiency syndrome (AIDS). The problem of immunosuppression in microgravity was first noted dur...

How sweet it isn't: Repeat episodes of low blood sugar spell diabetic disaster

...ow that administration to the brain of urocortin I suppresses the counterregulatory response to hypoglycemia for at least 24 hours in rats. They show that urocortin I, which activates corticotrophin-releasing factor receptor 2 (CRFR2), impairs the sensitivity of glucose-sensing neurons in the brain. In contrast...

New mechanism explains glucose effect on wakefulness

...ucose-inhibited neurons, it is unknown how glucose suppresses the electrical activity of orexin cells." What's more, they wrote, "Because the sensitivity of orexin cell firing to the small changes in extracellular glucose that occur between normal meals has never been tested, the daily physiological relevance o...

Marijuana-derived drug suppresses bladder pain in animal models

...ncipal active ingredient of marijuana--effectively suppresses pain in hypersensitive bladder disorders such as interstitial cystitis (IC), according to animal model study results presented today at the annual meeting of the American Urological Association. IP 751 is a potent anti-inflammatory and a powerful ana...

Large NCI grant will test the effect of Tibetan yoga on women with breast cancer

.... "There is extensive evidence showing that stress suppresses cell-mediated immunity, a component of the immune system involved in tumor surveillance. Tibetan yoga also might have an impact on patients' hormonal activity."...

International Congress of Neuroendocrinology in Pittsburgh June 19-22

...ater in life A newly discovered neuropeptide that suppresses all stages of sleep and may represent a target for the treatment of schizophrenia Results of clinical studies looking at oxytocin for reducing psychosocial stress during marital conflict and growth hormone for increasing muscle mass and physical act...

Gene variations linked to brain aneurysms

... Similarly, another variation (-174G>C), which suppresses the production of Il-6, was around 2.5 times as common among the comparison group as it was among the patients with aneurysm. As yet, it is not known at whether these variations come into play at the development, progression, or rupture stages, say ...

Brain study considers motor function, cognition with alcohol consumption

...the lead author on the paper. "Alcohol selectively suppresses the brain areas needed to incorporate new informat... 6, 2006. The study found that alcohol selectively suppresses cognitive activity in the frontal and posterior parietal brain regions; these are regions most commo...

St. Jude unlocks mystery of very aggressive leukemia

... in this disease is unknown. The Arf gene normally suppresses the proliferation of cells carrying cancer-causing mutations such as Bcr-Abl, according to Charles J. Sherr, M.D., Ph.D., a Howard Hughes Medical Institute investigator and co-chair of the St. Jude Department of Genetics and Tumor Cell Biology. Arf a...

Bone resorption cells offer drug targets for osteoporosis, rheumatoid arthritis, and more

...y has discovered novel mechanisms of how cortisone suppresses the osteoclast, which then leads to suppression of the cells that create new bones. Because cortisone-induced osteoporosis is such a common form of osteoporosis, much more research is needed in this area, says Dr. Teitelbaum....

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(Date:7/30/2014)... Red Queen in Lewis Carroll,s Through the Looking ... National University of Singapore improved a 35-year-old ecology ... decades to millions of years. , The new ... incorporates the "Red Queen Effect," an evolutionary hypothesis ... which suggests that organisms must constantly increase their ...
(Date:7/30/2014)... until they hatched 4.5 years later, according to a ... PLOS ONE by Bruce Robison from Monterey ... have a single reproductive period during their life, where ... eggs until they hatch. Shallow-water octopuses typically care for ... is known about the brooding of deep-sea species. Using ...
(Date:7/30/2014)... (ACS) announced today that David L. Kaplan, Ph.D., will ... & Engineering as editor-in-chief. With the first issue ... will feature high-quality research in the rapidly burgeoning field ... materials that interact with living or biological systems. , ... tremendous growth in the field of biomaterials over the ...
Breaking Biology News(10 mins):Classic Lewis Carroll character inspires new ecological model 2Classic Lewis Carroll character inspires new ecological model 3Deep-sea octopus has longest-known egg-brooding period 2ACS Biomaterials Science & Engineering: Brand-new journal launches in 2015, names editor 2
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