Cancer cell communication exposed
...eved its control on the function of important cell surface molecules, such the Eph and Ephrin cell positionin...e to regulate the communication between these cell surface molecules, which are found at high levels in many human cancers, by preventing the function of ADAM,...New screen-and-treat methods for cervical cancer significantly reduce cancer precursor lesions
...ses a specially designed microscope to look at the surface of the cervix. The study, intended to combat these financial and systematic hurdles, was approved by the institutional review boards of Columbia University Medical Center and the University of Cape Town (Cape Town, South Africa). The internationa...Protein suppresses prostate cancer, enhances effects of vitamin E
...cer cell growth. A cell can send messages from its surface to the nucleus through a set of chemical reactions known as a signaling pathway. Yeh and her team identified a specific pathway disrupted by TAP. The disruption by TAP suppresses cancer cell growth. The pathway involves two proteins, phosphatidylinos...Primrose oil component cuts levels of cancer-causing gene Her-2/neu
...sands of Her-2/neu molecules commonly found in the surface of overexpressing cancer cells, GLA would be more efficient to reduce Her-2/neu levels by preventing the transcription of few Her-2/neu gene copies," Menendez said. "Considering that activation and overexpression of the Her-2/neu oncogene are crucial...ERS altimeter survey shows growth of Greenland Ice Sheet interior
...and ERS-2, the team determined spatial patterns of surface elevation variations and changes over an 11-year period. The result is a mixed picture, with a net increase of 6.4 centimetres per year in the interior area above 1500 metres elevation. Below that altitude, the elevation-change rate is minus 2.0 cm ...New malaria vaccine shows promise in early clinical trial
... a vaccine based on MSP3, a protein present on the surface of the malaria parasite, with very encouraging results. As the researchers report in the international open-access medical journal PLoS Medicine, most of the 30 healthy volunteers who received the vaccine developed strong, specific, and in some cas...Vaccine for follicular lymphoma
... the lymphatic system the cells of which present a surface protein in fact, an immunoglobuline - that can be used as a target. The vaccine, known as idiotypical, is produced from this protein and its aim is to provoke a reaction from the immune system of the patient. Normally the patient does not react agai...New RSV treatment for at-risk infants under study
...oclonal antibody therapies target protein F on the surface of RSV which helps the virus spread from cell to cell. The virus' ability to reach the lungs results in hospitalization of about 125,000 babies each year and death in 1 percent to 2 percent percent of those infants, according to data from the Nationa...How does Mycobacterium tuberculosis infect the lung?
...ads in the lung. In particular, they looked at the surface of the lung cells, because this is the part direct...with TB had much more the DC-SIGN protein on their surface than macrophages from patients with other diseases or from the control individuals. They then took...Cells derived from heart stem cells can repair heart attack damage
...s most like cardiac stem cells, while cells on the surface had properties similar either to myocytes (heart muscle cells with the ability to contract) or to cells that could develop into smooth muscle or blood vessel lining. "We don't know yet the purpose or advantages of this organization," says study lead ...Early results using therapeutic pancreatic cancer vaccine show promise
...tumor vaccine where they encounter antigens on the surface of the irradiated cells. Then, these newly armed immune cells patrol the rest of the patient's body to destroy remaining circulating pancreatic cancer cells with the same antigen profile. Patients get one vaccine injection eight to ten weeks after su...Journal of Rehabilitation Research & Development tipsheet
...ty, and cosmetic features of the spine. Ground surface impacts wheelchair propulsion, pg 447 Data from a manual wheelchair propulsion study indicate that different ground surfaces impact wheelchair pro- pulsion ability, revealing conditions contributing to arm overuse in people who use wheelchairs. Elev...Jefferson and Delaware researchers combine tiny nanotubes and antibodies to detect cancer
...s that home in on target protein "antigens" on the surface of cancer cells. The antibodies were specific for ...er expression of IGF1 receptors." The cells have a surface protein that is recognized by the antibody on the nanotubes. The current spike occurs only if a targ...Brain structure associated with fear inhibition also may influence personality
...ntromedial prefrontal cortex an area on the lower surface of the brain that includes the mOFC and is believed to inhibit the activity of the amygdala, a structure known to be involved with fear. The current report combined the data analyzed in that study published in the July 26, 2005, Proceedings of the ...Cellular molecule spurs growth of prostate cancer
...arp's UNC laboratory was the first to clone a cell surface tyrosine kinase, Mer. "We saw that Mer was expressed at reasonably high levels in prostate cancer cells. And so Dr. Nupam Mahajan, the study's first author, decided to look at whether Mer had an effect on prostate cancer growth signaling," Earp said...Antibacterial coatings cut infection rates
...s for attaching the furanones, and analysing their surface properties and chemical composition to get a detailed understanding of how they are best applied. Al-Bataineh's research has been supervised principally by Professor Griesser and co-supervisor Dr Leanne Britcher at The Wark TM , with co-supervision b...Hair follicle stem cells contribute to wound healing
...al. In addition, the stem cells respond rapidly to surface wounding-within two days-by generating short-lived... as they migrated from deep within the skin to the surface wound site. The mouse stem cells express a reporter gene that encodes an enzyme, which can be detect...Fat tissue surrounding thoracic arteries may be beneficial
...rafting, to give them access to more of the artery surface and making the procedure easier to perform. Dr. Lee said the next step will be to determine if clinical evidence shows that leaving the fat tissue intact during CABG surgery provides for better blood flow than is shown by patients in which the fat ti...The heat is on: Why some cholesterol-lowering drugs cause hot flashes
... nicotinic acid activates GPR109A expressed on the surface of fat cells it induces a lowering of lipid levels...staglandins that cause blood vessels near the skin surface to dilate, resulting in the characteristic flushing response. In an accompanying commentary Nicholas...... nicotinic acid activates GPR109A expressed on the surface of fat cells it induces a lowering of lipid levels...staglandins that cause blood vessels near the skin surface to dilate, resulting in the characteristic flushing response. In an accompanying commentary Nicholas...