Mayo Clinic researchers redefining how heart functions
...laxation phase by muscle layers close to the outer surface of the pumping chamber." Partho Sengupta, M.D., lead author of the study who designed the project under the mentorship of Drs. Belohlavek and Khandheria, notes further: "By a brief shortening, cardiac muscle in these outer layers helps to 'unwrap' t...As Montreal Conference considers deforestation issues, ESA presents space solution
...irculation and a steady rise in average global sea surface levels. In the atmosphere, satellites are also able to quantify aerosol types and concentrations which play an important part in regional climate and even count the number of aircraft condensation trail 'contrails', which have a climate impact by ...UCSD researchers report results of children's backpack study
...houlder and 110 mmHg on the right shoulder -- skin surface pressures that are more than double and triple the threshold for reduced blood flow. Murthy states, "The concern of heavy backpacks and back and shoulder pain to parents is not new. However, the objective data that we have published is new and impor...Advance in cholera bacteria points to new treatment and vaccine
... water sources. V. cholerae attaches to the outer surface of plankton, made up of a carbonate substance call... and multiplies. Humans do not have chitin in the surface of intestinal cells, where the bacterium takes hold, and researchers have been searching for another...Mountainous plateau creates ozone 'halo' around Tibet
... continues above the top of the obstruction to the surface of the water, leaving a column of still water above the object. Scientists treat air as a fluid, and Moore says that the Tibetan plateau acts like an obstacle, creating a column of stagnant air above the mountainous region. Because the plateau's infl...How the neuron sprouts its branches
...ut mammalian neurons in the brain are huge, with a surface area about ten thousand times that of the average ...brane components came from to generate the complex surface of growing dendrites. And we thought these remote structures we had discovered in dendrites called G...Tiny self-assembling cubes could carry medicine, cell therapy
... in a lab solution, the metallic hinges melt. High surface tension in the liquified solder pulls each pair of adjoining squares together like a swinging door. When the process is completed, they form a perforated cube. When the solution is cooled, the solder hardens again, and the containers remain in their ...National study improves outcome for pediatric AML
...l combinations of proteins that appear only on the surface of leukemic cells. This allowed the investigators to quickly and accurately determine the percentage of such cells in bone marrow samples. Doctors used MRD measurements made after induction to determine if the treatment was eliminating enough leukemi...Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection
...irectly block the expression of the protein on the surface of these cells may have several advantages over th...which there are approximately 10,000 copies on the surface of each T-cell. In contrast, brief exposure of T-cells to Sangamo's ZFNs has been shown to result i...Smoking associated with severity of psoriasis
... disease characterized by scaly red plaques on the surface of the skin. Although psoriasis is not a life-threatening disease, the disability experienced by patients with psoriasis is comparable with that of patients with other chronic illnesses, such as heart disease, diabetes, cancer, and depression, accor...Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
... be the first to demonstrate that a protein on the surface of nerve cells called the EP1 receptor is the switch, and that a specific compound, known as ONO-8713, turns it off. The finding holds promise for the development of effective alternatives to anti-inflammatory drugs called COX inhibitors, which hav...Successful treatment for acute heart failure remains elusive
...eart failure," says Dr. Gheorghiade. "And, on the surface it looks like we're successful at treating ACHF. Patients are treated, feel better and are discharged. The problem is that within 90 days of discharge, nearly 10 percent of patients die and about 30 percent are readmitted." Traditionally, cardiologi...MSG-2 will advance long-term monitoring of Earth's energy balance
...s directly reflected back by clouds or the Earth's surface or scattered backward by air molecules in the atmo...n the low-altitude troposphere or else by the land surface or ocean. The air, land or sea that absorbs this sunlight becomes heated up by it, and this heat is...Melanoma risk only partially associated vith exposure to UVB from sunlight
... often die or form a kind of curable cancer at the surface that is often nonmalignant and easy to remove by surgery or treat in other ways, he says. Melanoma, on the other hand, is now known to be resistant to chromosomal breaks from UVB radiation, which means that the cells chromosomes stay intact long eno...Research clarifies how brain replenishes memory-making molecules
...esh AMPA receptors appear to be placed on the cell surface at the cell body and then migrate along the arms o...selectively "silence" AMPA receptors on the neuron surface and show that receptors inactivated at synapses were not rapidly replenished by receptors inside the...Antibody therapy promising for pediatric neuroblastoma
...ought out and bound to a protein called GD2 on the surface of neuroblastoma cells. They also infused a special type of T lymphocytes called gamma-delta T cells, which attacked the cancer cells that were tagged by hu14.18. In order to stimulate the growth and activity of the gamma-delta cells, the researcher...Brain cell activity increases levels of key ingredient in Alzheimer's plaques
...ers cross the synapse and bind to receptors on the surface of the receiving nerve cell. Normal brain physiology produces amyloid beta and naturally clears it from the brain, so Cirrito conducted a series of follow-up experiments to try to get a sense for whether increased synaptic vesicle release was affecti...Structure of viral harpoon protein reveals how viruses enter cells
... difficult because the anchoring of F to the virus surface (or membrane) is important for holding F in this active state. The protein's structure could not be solved unless it was in the membrane, but solving a protein structure like this required that it be separated from the membrane. To accomplish this, t...UCSD laser technique sheds light on strokes
...lionth of a second) laser pulses to peer below the surface of the brain, the researchers snapped frames every second before and after the formation of the blood clot. They also measured blood flow in the arteries upstream and downstream of the clot. Remarkably, immediately following the formation of the cl......o molecules called integrins that project from the surface of cells, including neuroblastoma cells. Normally, integrin molecules anchor the cell to the extracellular matrix--the material outside the cell consisting of gel and fibers that support and provide structure to tissues. When cells become dislodged f...