Feeling safe and secure? CUMC scientists find it's all in the caudoputamen
...afety in terms of a reduction of fear, and it's no surprise that we found that the safety sound reduces neural activity in the amygdala," Michael Rogan says. But Rogan and Kandel also found that the safety signal traveled through other, previously unknown circuits that lead to the brain's caudoputamen, a regi...Monoclonal antibody cures West Nile virus-infected mice
...n a group of amino acids in that domain. "The big surprise for us was that all of the potently neutralizing antibodies appear to recognize the same general region of this domain," says Fremont. "It was very consistent--all the neutralizing antibodies that bind this domain adhere to that area; all the non-neu...MicroRNA study opens potential revolution in cancer diagnosis
...s have such potential diagnostic utility was a big surprise to us, and one we're keen to validate in future studies." MiRNAs were first identified in the worm C. elegans, and were shown to control development and differentiation of cells: When absent, certain cells went into abnormal rounds of cell division ...True cancer-causing genes revealed by new technique, say Stanford researchers
...ld see the effects of mutations they induced. "The surprise in this study was that what is perhaps the most famousmutation in this cancer didn't cause melanoma," Khavari said. A mutation ina gene for the protein B-Raf shows up in the majority of all melanomacases. "This suggests that it must be doing somethin...Nutritious frozen foods can play role in weight-loss programs
...ries and lost weight. Many subjects reported their surprise in feeling satiated by the diets. Subjects who followed the frozen-entree diet lost more weight (7.4 kg or 16.3 pounds) compared with the subjects who made their own meals following the food pyramid (5.1 kg or 11.2 pounds). Also, the average BMI decr...Search for bipolar gene, toll of disease topics of conference call briefings June 16, 17
...timating 1 percent prevalence. Its cost comes as a surprise as well, with a near $26 billion annual price tag in the United States. Bipolar disorder accounts for nearly half of all suicidal deaths each year. How best to prevent these suicides? One study finds lithium, one of psychiatry's oldest drugs, the mos...Poly/mono balance important to cholesterol-lowering diet
...s in the study participants -- and they did. The surprise was the fact that the olive oil diet, which is also low in saturated fat, did not lower cholesterol levels compared with the average American diet. Also surprising was that the greater percentage of PUFAs in the NuSun sunflower oil diet did not incr...Study: Vasodilators first choice for some heart patients
...tal at The Ohio State University, the findings may surprise some in the medical community, particularly those who favor the use of positive inotropes, the group of drugs that includes dobutamine and milrinone. "This is a significant finding from a large population of patients and will certainly aid in the d...MCG faculty contribute to textbooks on geriatric, pediatric hypertension
... pressure," says Dr. Prisant. "The thing that will surprise you is that most of those folks do not have their blood pressure under control." Three MCG faculty members and a research manager also have contributed to the first textbook on "Pediatric Hypertension," which provides practitioners an overview of thi...Hospice referral rates increase with intervention improving communication
... nursing homes," the authors write. "If there is a surprise in these findings, it is that such a simple, inexpensive, and easily exportable intervention can contribute so much to improving care. As Americans spend more time in nursing homes near the end of life, it will becomes increasingly important to empha...HIV therapy success rates similar in developing and developed world, study shows
... this intuitively makes sense, it was a satisfying surprise to be able to demonstrate the impact of payment for ART on its success. This has important potential implications for ART program development, which is ongoing in many resource-poor settings around the world," Doucette said. According to the latest n...Common C-section method leads to unnecessary scars, Stanford study finds
... current thinking among many surgeons. "This was a surprise finding," said Deirdre Lyell, MD, assistant professor of obstetrics and gynecology and lead author of a paper appearing in the August issue of Obstetrics and Gynecology . "We were fully expecting to find that closing the peritoneum at caesarean deli...At Johns Hopkins: Emphasis on improved care and faster access to services shortens hospital stays
...s were found in all cases under review, and to the surprise of many, delays were frequently fixable. Over the four years of the program, the Hopkins team reviewed more than 200 different procedures and more than 5,000 patient files. Among them were patients with congestive heart failure, for which patients w...Surprising new study shows periodontal disease affects young adults, boosts pregnancy problems
...0s had periodontal problems with no symptoms was a surprise to us since most people assumed that you don't get periodontal problems until you are 35 or 40," White said. "But nobody had looked at wisdom teeth systematically before in a large study like this." In the evaluation of data from 1,020 higher-risk ob...Large sinus tumors can be removed endoscopically, study finds
...ence rate of up to 44 percent, a fact that did not surprise Dr. Kountakis. "When you deal with a tumor, even a benign tumor, sometimes it's better to cut it out with clean margins, do what's called an oncologic surgery. In this paper we are discussing tumors that are very large. To be able to do that, you wo...UNC wins eight top NIH 'Roadmap' grants, more than any other university in the country
...pporting Roadmap and Roadmap-like efforts, it's no surprise that UNC investigators have done even better this year, he said. "To our knowledge, no other university has dedicated so much infrastructure to supporting interdisciplinary collaboration within the federal Roadmap initiative." The new funding will ra...Sandia researchers determine that common anthrax sampling methods need improvement
...nt, leaving 72 percent on the coupons. The biggest surprise was that the vacuum method collected only 20 percent of the spores, leaving 80 percent on the surface. "Before this study, the vacuum method was the most highly recommended sampling method by the CDC," Brown says. "As the result of our study CDC no l...A new blueprint to aid physicians in predicting risk for type 1 diabetes
... had an 80 percent risk after just 6.7 years. "The surprise was that by using these older assays in combination with the newer tests, we were able to more accurately predict type 1 diabetes in the family members of those with type 1 diabetes," Dr. Pietropaolo said. In addition, family members with a certain s...Study shows escalating climate change impacts
...ramework to deal with and plan for climate-related surprise impacts In September 2003, a Scoping Conference for the CCF project was held at the United Nations in New York and involved more than 80 participants from multiple scientific disciplines, corporations, UN agencies and non-governmental organizations....New survey reveals older Americans' attitudes toward sleep and healthy aging
...igh levels of anxiety," said Dr. Butler. "It is no surprise that this stress and the need for round-the-clock care often interfere with getting a good night's sleep." About the Survey and Consensus Conference Findings of the survey were presented at the ILC's Sleep and Healthy Aging Scientific Consensus Con...