A possible new phase for rheumatoid arthritis treatment
...cesses that maintain long-term inflammation of the synovium in rheumatoid arthritis have been well studied, those initiating the inflammation have not, and very few groups have studied the pathology of rheumatoid arthritis within the first few weeks after the onset of symptoms. Karim Raza and colleagues, from...Children's receives one of only two national pediatric rheumatology training grants
...her project, delivering gene therapies to diseased synovium of children with JRA is being investigated to impr...r. Hirsch says. "We are delivering the gene to the synovium itself. Synovial cells then incorporate it into their genetic machinery and begin to make the protei......ment of technologies for specific targeting of the synovium and delivery of therapeutic agents," the authors a... of identifying novel molecular targets within the synovium for optimizing the diagnosis and management of RA....