Tag: "tamoxifen" at medical news
Hot flashes may be welcome sign in women with breast cancer, study says
CHICAGO, June 4, 2007 -- Women on tamoxifen
therapy who reported having hot flashes were less ...hes and breast cancer progression by measuring the tamoxifen
metabolites in breast cancer survivors. ...
Women with breast cancer do not get potentially life-saving information, survey reveals
...been shown to be significantly more effective than tamoxifen
in reducing the chance of breast cancer coming back after surgery in postmenopausal women with hormone-sensitive early breast cancer. Half of the women surveyed were being treated with tamoxifen, indicating that many women are not getting the mo...
Alternative hormone treatment could help fight against breast cancer
...t with LHRH agonists combined with chemotherapy or tamoxifen
gave an additional benefit, reducing recurrence of...with higher-risk disease, chemotherapy followed by tamoxifen
should still be the standard approach, with the addition of an LHRH analogue a reasonable considerat...
Other highlights in the May 2 JNCI
...rgone a hysterectomy appear to benefit from taking tamoxifen
to prevent breast cancer, according to an extended...o significant reduction in breast cancer risk with tamoxifen
use. However, the National Surgical Adjuvant Breast and Bowel Projects Breast Cancer Prevention Tria...
USC-led study suggests exercise reduces risk of developing invasive breast cancer
...namely the use of drugs that block estrogens, like tamoxifen
or raloxifene. These drugs seem to be effective in reducing risk of ER-positive cancers, but do not impact the occurrence of ER-negative cancers," says Bernstein. "This study confirms that breast cancer risk is influenced by consistent participati...
Early switch to an aromatase inhibitor increases survival
...uce the risk of breast cancer recurrence. However, tamoxifen
is associated with increased risk of death from ot...strokes and endometrial cancer. Despite this risk, tamoxifen
and another drug in this class, raloxifene, remain an extensively used and popular treatment. Aro...
Hormone drug type makes survival difference in advanced breast cancer
...ancer treatments that also affect estrogen include tamoxifen
and progestins. Tamoxifen is the most widely used hormonal treatment in advanced breast cancer; however, it carries a risk of blood clots and other rare but potentially serious side effects. Bliss said that the review found very little reliable dat...
Adding radiation decreases breast cancer recurrence
...en also benefit from the recommended five years of tamoxifen
treatment for hormone responsive tumors. Among wom...ional recurrence. These results held regardless of tamoxifen
treatment, suggesting that adjuvant radiation treatment was highly effective. In addition, the re...
Tamoxifen discontinuation rates surprisingly high in clinical practice
... a quarter of women treated for breast cancer stop tamoxifen
within one year, a rate twice as high as indicated...o reveals that over one third of women have ceased tamoxifen
treatment. Tamoxifen is a selective estrogen receptor modulator that inhibits the stimulatory eff...
Radiation therapy reduces cancer recurrence in older breast cancer patients
...mpectomy and five years of treatment with the drug tamoxifen
can dramatically reduce the risk of both cancer recurrence and new tumors in older women with early breast cancer, according to researchers from Wake Forest University School of Medicine and colleagues. "While these treatments are standard care for...
Genomic tests improve prediction of breast cancer response to chemotherapy, hormonal therapy
...st cancers express the estrogen receptor (ER), but tamoxifen
and other anti-estrogen therapies only benefit abo...erapy was then tested in 267 patients who received tamoxifen
without chemotherapy for five years after surgery. "There was a strong relationship between their SE...
Pioneer of oral rehydration therapy receives Prince Mahidol Award
...Sir Richard Peto, whose work argued for the use of tamoxifen
in the treatment of breast cancer; and Drs. Tore Godal and Adetokunbo Oluwole Lucas, who jointly won the award for their contribution toward the development of the special Program on Tropical Disease Research. See here for a full listing of previous ...
Long-term safety results released for breast cancer drugs
Anastrozole is tolerated better than tamoxifen
for the treatment of postmenopausal women with ear...AC) trial compared use of anastrozole with that of tamoxifen
in more than 6000 postmenopausal women with breast cancer that had not spread to other parts of the ...
Tamoxifen for breast cancer prevention does not benefit most women
..., Canada. In addition, the researchers showed that tamoxifen
is an extraordinarily expensive cancer-prevention ...ncer, there is a very small likelihood that taking tamoxifen
will reduce mortality," said Joy Melnikow, professor of family and community medicine at UC Davis Sc...
Study uncovers 'significant' functional differences of novel estrogen receptor
...ed surprise that anti-estrogen treatments such as tamoxifen
stimulate cell growth and that the anti-estrogens ...ings, the study said, support the conclusion that tamoxifen
functions as both agonist and antagonist of estrogen signaling and that the expression of hER-a36 ma...
Study evaluates benefits and risks of tamoxifen and raloxifene for reducing risk of breast cancer
Raloxifene and tamoxifen
are both effective in reducing the risk of invasiv...The study patients were randomized to receive oral tamoxifen
(20 mg/day) or raloxifene (60 mg/day) over five years. "There were 163 cases of invasive breast c...
Better survival seen for early breast cancer patients switched from tamoxifen to Aromasin
...nts who switched to Aromasin after 2 to 3 years of tamoxifen
were 17% more likely to be alive and were 25% less...their cancer return than patients who continued on tamoxifen
for a full 5 years of therapy. "Exemestane is the only anti-hormonal therapy that has been shown to...
Italian researchers find fenretinide cuts the risk of second breast cancers in young women
...especially given that the patent would run out and tamoxifen
was already on the market for treatment and had more efficacy data from large international trials." Dr Decensi added that a preventive trial of fenretinide would be a clear example of the importance of health-care provider and community support for ...
Benefit of chemotherapy in breast cancer depends on estrogen-receptor status
... use by the cancer cells. "Our analysis shows that tamoxifen
works very well for a number of years and taken as...the prevailing wisdom that with the development of tamoxifen
and newer selective estrogen receptor modulator drugs, the benefits of medical science have been pri...
Newer chemotherapies improve outcomes for some types of breast cancer
...risk reductions for ERpositive tumors treated with tamoxifen
were 9 percent, 12 percent, and 8 percent in the t... patients who have ERpositive disease treated with tamoxifen
are modest at best. Whether such patients should opt for chemotherapy will depend on their attitudes...
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