NIH grant to support research on new treatment for severe OCD
...ors, similar to those used in heart pacemakers, in targeted brain regions to block the nerve signals believed ...VC) and the adjacent ventral striatum (VS) will be targeted for stimulator placement. Researchers believe these regions are at the intersection of many importan...Procedure for irregular heartbeat gives long-lasting relief & improves quality of life
...ere ablation takes place. The radio wave heats the targeted areas of tissue, a process called ablation, but spares nearby tissue. The new study was the first ever designed specifically to separate the ablation procedure's effects from those of medications and cardioversion, which are often used temporarily af...Community-wide health program slows creep toward heart disease
...essure. The cardiovascular disease prevention plan targeted residents of Limburg, a province on the southern edge of the Netherlands. The campaign, dubbed Hartslag Limburg -- Dutch for Heartbeat Limburg -- included nearly 800 programs from bicycling clubs and supermarket education tours to pamphlet distributi...Stanford doctors spotlight fatal flaw in multiple sclerosis drug trial
...ho are likely to suffer severe disability from the targeted disease - and for whom there are no other options. In other words, those who have tried all the other available therapies. That is almost the reverse of what happened in the Tysabri trial, which excluded the most severely affected patients. "A big mi...Depression, anxiety in girls linked to higher body mass index in women
...sful prevention is likely to require interventions targeted toward many factors, no one of which, alone, is sufficient to prevent obesity," the authors write. An average-height woman diagnosed with depression at age 14 would weigh about 10 to 16 pounds more than a non-depressed woman by the time both reached...Reducing teens' intake of sugary drinks
... noncaloric beverages." Although the intervention targeted only the home environment, previous research suggests that home is where adolescents get the majority of their food and beverages. "It should be relatively simple to translate this intervention into a pragmatic public health approach," the authors ...New strategy developed to study disease: Reveals insights into cancer and treatment leads
...kL, a signaling protein not previously known to be targeted by Src's actions. The study also found direct evidence that Src activates MAP kinase pathways, which help transfer information from growth factors, molecules that aid in the development of cancer cells. Previously the role of Src in these pathways ...Predictive risk factors by gender will help diagnose and treat CVD in women
...tter understood, more women need to be included in targeted clinical trials and health care professionals must better understand the role age plays in women's risk of heart disease, according to the results of an ESC Policy Conference on CVD in Women. Fifty-five percent of European women die from CVD each yea...Exposure to fine particle air pollution linked with risk of respiratory and cardiovascular diseases
...to be identified so that control strategies can be targeted efficiently."...New test to detect rare proteins in blood
...s laboratory established many of the principles of targeted therapy for Her2/neu tumors and the prototype anti...howed that early treatment of Her2/neu tumors with targeted monoclonal antibodies in animal models led to far more significant prevention of tumor growth as wel...How can we protect patients with weakened immune systems from influenza?
...teams will measure T cell and B cell counts in the targeted patients. Both types of cells play important roles in the immune system. T cells that recognize and fight influenza may help predict whether a patient will produce protective antibodies after vaccination. Producing those antibodies is the job of B ce...Pregnancy complications increase women's risk of heart disease, death
...group of patients who would appear to benefit from targeted prevention efforts, including smoking cessation efforts. "Given the high percentage of women who continue to smoke during their pregnancy, targeting this behavior would not only benefit the health of the fetus but reduce the mother's future risk for ...New drugs improve bone marrow cancer outlook
...genesis and substantial development of molecularly targeted therapy."...Potential prostate cancer treatment improvements discovered by researchers at Cedars-Sinai
... trial to demonstrate the clinical benefit of this targeted therapy."...Protein sorting in pigment cells sheds light on melanoma, Alzheimer's disease
...ased outside the cell, the exosomes themselves get targeted to dendritic cells. Then exosomes ferry Pmel17 and other melanoma antigens from the melanoma tumor cell to the dendritic cell. "Exosomes are a very hot topic now in cancer immunotherapy because dendritic cells are good at taking them up, processing ......od of response to standard therapies and molecular targeted treatments. 4. Define metastatic breast cancer guidelines Most women still die from metastatic breast cancer. The general criteria on how to manage metastatic breast cancer need to be defined. Specific guidelines can help the patient and the clinici...U-M study: Program to boost elderly flu vaccination could save lives
...al impact for increasing vaccination rates among a targeted group through a program led by the federal government. So Davis, along with second-year U-M Medical School student Mitesh Patel, analyzed the cost-effectiveness of a hypothetical 10-year federally sponsored flu vaccination promotional program aimed a...Serendipity versus planning - cancer drugs of the future?
...pidermal Growth Factor Receptors (EGFR), which are targeted by other successful agents such as trastuzamab (Herceptin), cetuximab (Erbitux) and gefitinib (Iressa). The first two are monoclonal antibodies, against ErbB2 and ErbB1 respectively, the third is a 'designer' drug. Trials of the combination of antib...Fighting inflammation with targeted liposomal therapy
...y.com/journal/arthritis ), indicate the promise of targeted liposomal therapy for rheumatoid arthritis patient...s injection of 1 milligram of DEXP encapsulated in targeted RGD peptide-exposing polyethylene glycol liposomes (RGD-PEG-L). Another group was injected with the......teroids were encapsulated in RGD peptide liposomes targeted to bind to inflamed cells in the walls of blood vessels. The steroid treatment was delivered rapidly and worked effectively to reduce synovial inflammation, with no signs of the conventional side effects. Further potential targets with...