Tag: "telomerase" at medical news
Variant in gene associated with telomeres predicts longer survival of deadly brain tumor
... the cell dies. But in cancer, it is believed that telomerase
is activated and intervenes to keep telomeres from shortening, allowing for unlimited cell division. The research group looked at genetic variation of hTERT because abnormal expression of the gene contributes to unregulated cell growth, and expressio...
Arteries bio-engineered from elderly cells
...ng. Counter had previously cloned the hTERT (human telomerase
reverse transcriptase subunit) component of the en...trength to vessels." Additionally, she said, using telomerase
expression to extend the lifespan of the vessels created from older cells proved to be an effective ...
Measuring certain enzyme activity in urine shows promise for detection of bladder cancer
...the markers investigated for this purpose has been telomerase
(a certain enzyme) activity in urine. Maria Aurora...udy to define the diagnostic accuracy of different telomerase
activity cutoff values in terms of sensitivity and specificity. The study included 218 men (84 healt...
A little telomerase isn't enough
... exposed. In stem cells, however, a protein called telomerase
normally maintains the telomeres' length, allowing... engineered to have just half the normal amount of telomerase
can't maintain their stem cells' chromosome ends, showing that a little telomerase
isn't enough. In ...
Wear and tear of stress: the psychoneurobiology of aging
...es. These people are more likely to have decreased telomerase
activity. Telomeres are enzymes that regulate how many times an individual cell can divide. Telomeric sequences shorten each time the DNA replicates, which is a process that happens prior to cells dividing. When at least some of the telomeres reach a...
Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
...gators. Researchers compared telomere length and telomerase
activity in biopsy specimens from 38 patients with GERD and 16 control patients. This new line of research suggests that the continuous acid bath affecting esophageal cells causes them to divide more frequently in order to regenerate the damaged lini...