Report calls for new directions, innovative approaches in testing chemicals for toxicity to humans
WASHINGTON -- Recent advances in systems biology, testing in cells and tissues, and related scientific field...ironmental Protection Agency -- which oversees the testing of many agricultural, commercial, and industrial chemicals -- asked the Research Council to develop ...Avian influenza on people's minds
... as well as the safeguards in place, which include testing of flocks and Federal inspection programs. Moreover, the USDA states, Cooking poultry, eggs, and other poultry products to the proper temperature and preventing cross-contamination between raw and cooked food is the key to safety. However, accordi...UK scientists set their sights on cure for AMD
...g in conjunction, they will be respectively safety testing the cells in Sheffield, confirming that the cells are RPE cells and preparing them in a form for transplant at the Institute of Ophthalmology, and developing the strategies for the surgery and patient selection based on studies on transplanting autol...Dartmouth's alternative breast imaging techniques sort abnormal from normal tissue
...shed a paper with results from a five-year project testing three new imaging techniques to examine breast abnormalities, including cancer. The study finds that the new methods of electromagnetic imaging offer a high contrast and the ability to distinguish between healthy breast tissue and abnormal tissue. Th...GSK announces launch of largest ever Phase III trial in lung cancer treatment
...eased last year at ASCO 2006, and support expanded testing of this novel cancer immunotherapy, said Paul A. Bunn Jr., M.D., James Dudley Endowed Professor of Oncology, Professor of Medicine and Director of the University of Colorado Cancer Center, Aurora, Colorado. This approach represents a potentially mome...USC researchers show that molecular markers predict tumor recurrence
...d at USC medical facilities between 1999 and 2007, testing whether a specific pattern of polymorphisms in 33 genes involved in cancer progression predicted tumor recurrence. Of the 197 patients who participated, 72 patients had stage II and 125 had stage III colon cancer. Researchers identified the vascula...New drug shows promise in treatment of advanced thyroid cancer
...ates in 2007 and 1,530 deaths. A follow-up trial testing axitinib in patients who have not responded to standard chemotherapy is ongoing. ...Genetic variations may predispose some men to suicidal thoughts during treatment for depression
...d, this finding would suggest that pharmacogenetic testing could facilitate the identification of the small subset of individuals at greater risk during short-term antidepressant treatment, the authors conclude.(Arch Gen Psychiatry. 2007;64:689-697. Available pre-embargo to the media at http://www.jamamedi...Stanford researchers track human stem cells transplanted into rat brain
...urrounding tissue. The research group is currently testing whether those transplanted cells repaired stroke-i...se. Steinberg said he and others are interested in testing these or other stem cells as a way of treating a wide range of diseases....Drug shows activity against brain metastases
...drug, also known as Tykerb, should undergo further testing in combination with other drugs as a treatment for breast cancer that has spread to the brain. Results of this study indicate that lapatinib, when given alone, has modest but real activity against brain metastases in women who have had multiple pri...Brain-boosting pill alleviates post-chemotherapy fogginess
...ncer, participated in an eight-week clinical trial testing the effects of modafinil (Provigil). All women took the drug for the first four weeks. During the next month half of the women continued to receive the drug while the other half took an identical looking placebo pill. The women who took modafinil for...Nonhormonal drug reduces hot flashes in men treated for prostate cancer
...other reasons. Since then, several clinical trials testing gabapentin in women found that a dose of about 900 milligrams a day decreased hot flashes by about half -- the same dose and a similar degree of effectiveness discovered in Dr. Loprinzis clinical trial. Men participating in this study had a mean a...Genetic mutations identified for type of gastric cancer
...e obtained for full CDH1 genetic screening because testing a single mutation can be readily performed on suboptimal DNA from archival tissue samples."...Targeted, oral agent Enzastaurin shows favorable results
...er solid tumors. Specifically, the data in-cluded: testing enzastaurin on cell signaling, proliferation and apoptosis in breast cancer, testing in Phase I/II with radiation combination therapy for first-line treatment of glioblastoma multiforme...Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
...cules in disease conditions. The group is also testing the effects of adiponectin in conditions mimicking diabetes by exposing cells in the laboratory and blood vessels in animals to high glucose levels. "High glucose also causes dramatic inflammatory changes in the blood vessel lining," Dr. Goldstein sa...Journal Sleep: Longer CPAP use at night can normalize one's daytime functioning
...onths of CPAP, the participants completed a day of testing that included measures of daytime sleepiness and functional status. The findings indicated that a greater percentage of participants impaired prior to the initiation of CPAP achieved decreased daytime sleepiness and enhanced functioning to normal l...Study explains why patients with OSA are at higher risk for cardiovascular disease
...ls. The OSA patients were given polysomnographic testing to verify the diagnosis. This involved evaluating brain waves, electrical activity of muscles, eye movements, breathing rates, blood pressure, blood oxygen saturation and heart rhythm, as well as direct observation of patients during sleep. The men...TB test offers patients quicker and easier diagnosis
...s effective as other more invasive and complicated testing methods, which take three days. For the new test...ch causes most cases of TB. Other procedures for testing for TB are gastric washing and bronchoscopy with bronchoalveolar lavage. These invasive procedures i...Study tests oral insulin to prevent type 1 diabetes
...n the study, University of Florida researchers are testing whether an insulin capsule taken by mouth once a d...e previous three months. Also under way is a study testing whether a combination of two drugs approved by the FDA to prevent rejection after an organ transplan...Mayo researchers discover overdiagnosis of long QT heart syndrome
...nalin stress testing, and genetic testing. Genetic testing for this condition has been available as a clinical diagnostic test for only three years. A number of treatments can then be prescribed. Warning signs include: Sudden fainting spells or seizures -- especially during exercise or following an ...