Sucampo submits new drug application for lubiprostone
...the agent has been shown to work locally in the GI tract by activating specific chloride channels (a protein that carries chloride) on cells lining the small intestine, increasing intestinal fluid secretion. This increased fluid level softens the stool, promotes spontaneous bowel movements, and reduces ab...Many parents fail to set rules to limit children's exposure to tobacco smoke, according to new study
...rganization. Higher incidence of lower respiratory tract infection (such as bronchitis and pneumonia) as well as middle ear diseases and worsening of asthma have been attributed to environmental tobacco smoke. The results show the need for more public health efforts to ban smoking in public and other encl...Hormonal birth control, bacterial infections in women linked to increased shedding of type-2 herpes
...ble hormonal contraceptives is linked with genital tract shedding of HSV-2, which had been suggested by one prior study. However, they also found that two common types of bacterial infections, bacterial vaginosis (BV) and vaginal Group B streptococcus (GBS), were related to an increased risk of HSV-2 shedd...High risk of second cancers in survivors of childhood soft tissue sarcomas
... gender-specific cancers of the breast and genital tract were excluded, the risks were identical. Cohen et al. also found that second cancer risks were increased for all subtypes of childhood soft tissue sarcoma, with estimates ranging from 6-fold elevations in risk for fibromatous neoplasms to nearly 8-fo...Patients swallow 'camera-in-a-pill' to help doctors check for diseases of esophagus, GERD
... three minutes. It then glides down the esophageal tract taking about 2,600 color digital pictures (14 per second), which are transmitted, to a recording device worn around the patients waist, as a belt. After 20 minutes, the physician has sufficient video images to make an evaluation. The capsule is passe...A common bacterium leads to serious blood infection in many seniors, new study finds
...terium also associated with less dangerous urinary tract infections--poses a significant public health thre...man digestive tract, is a leading cause of urinary tract infections. Medical researchers have long known that E. coli is also a cause of bloodstream infectio...Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
...ving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloodstream t...f getting these large protein drugs through the GI tract intact, pharmaceutical scientists have looked at other ways to deliver protein-based drugs-such as v...Two studies document rise of superbugs in the environment
...richia coli, a familiar bug that can cause urinary tract infections--were involved in the upswing. The spread of multidrug resistance in bacteria appears to have two main causes, according to Aurora Pop-Vicas, MD, lead author of the Massachusetts study. The first is the intrinsic ability of bacteria to mut...Digestive Disease Week 2005 spotlights breakthrough research in digestive health
...fect of diet, weight and obesity surgery on the GI tract Novel targeted therapies for Crohn's and other inflammatory bowel diseases Technological advancements and improved efficacy in diagnosing GI disorders DDW is jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), th...Obesity linked to colorectal and esophageal cancers
...ex is now associated with cancers of the digestive tract and other serious GI disorders." The Effect of Bo...of developing esophageal cancer and other major GI tract disorders."...Nutrition gene key in regulating immune system
...y expressed in places such as the gastrointestinal tract and tonsils where the immune system routinely meets up with foreign substances it might want to ignore. Drs. Munn, Andrew L. Mellor and Simon J. Conway published a Science article in 1998 showing IDO's role in protecting the fetus from rejection by...Study shows grapefruit extract can heal stomach ulcers
...rial translocation (escape of bacteria from the GI tract to abdominal lymph nodes, in this example), higher blood endotoxin levels and more severe liver injury than male rats on the same diet or rats of either sex on the LDC diet (two-fold increase in total change), based on their intake of unsaturated fat...As morphine turns 200, drug that blocks its side effects reveals new secrets
...tion (a serious impairment of the gastrointestinal tract following surgery), opioid-induced itching, urinary retention, and possibly HIV. Opiates appear to increase the ability of HIV to infect certain immune system cells. In 2003, Moss reported that very small amounts of methylnaltrexone blocked these in...Steroid-free regimen with CellCept found comparable to standard therapy in liver transplantation
...ukopenia , thrombocytopenia, leukocytosis, urinary tract infection, hypertension, hypotension, peripheral edema, hypercholesteremia, hypokalemia, hyperglycemia, creatinine, BUN and cough increased, hypomagnesemia, diarrhea, constipation, nausea, vomiting, respiratory infection, dyspnea, lung disorder, pleu...Personalized immunosuppression with leading organ transplant therapy may optimize patient care
...ukopenia , thrombocytopenia, leukocytosis, urinary tract infection, hypertension, hypotension, peripheral edema, hypercholesteremia, hypokalemia, hyperglycemia, creatinine, BUN and cough increased, hypomagnesemia, diarrhea, constipation, nausea, vomiting, respiratory infection, dyspnea, lung disorder, pleu...Transplanting kidneys which have stones poses little risk to organ's viability
...stone in one patient grew and he developed urinary tract infections, which were remedied surgically. The investigators recommend that any patients transplanted with a kidney which has stones should have close follow up with tests dedicated to kidney stone detection. They also advise that the patient shou...Mutation in mouse circulatory gene mimics a form of congenital heart disease
...e in the brain do migrate to the heart and outflow tract areas; but, unlike in normal mice, the cells with mutations did not differentiate into smooth muscle cells. As a result, the cells did not form the structure that separates the aorta from the pulmonary artery. "This is the first evidence that a bloc...Medication orlistat appears helpful in improving weight management for obese adolescents
...e of therapy used. Orlistat is a gastrointestinal tract lipase (an enzyme) inhibitor which decreases intes...e placebo group. Mild to moderate gastrointestinal tract adverse effects (such as nausea, fatty/oily stools, and abdominal pain) occurred in 9 percent to 50 ...Children who are prone to ear infections have high rates of potential disease producing bacteria
...s associated with an increased risk of respiratory tract infections in adults and also with oral colonizati...o cigarette smoke is a risk factor for respiratory tract infections, including otitis media (ear infections). This study compared the frequency of potential ...Antibiotics appear to have little benefit for uncomplicated lower respiratory tract infections
Patients with uncomplicated lower respiratory tract infections, such as bronchitis, who were given ant...June 22/29 issue of JAMA. Acute lower respiratory tract illness is the most common condition treated in primary care, according to background information in...