Cancer vaccine innovator honored with prestigious Florey Medal
...oping penicillin. The award comes as a clinical trial is about to get underway in Vanuatu to establish how effectively cervical cancer can be controlled in the developing world, where disease rates are higher than in the Western world, through use of appropriate screening technologies and deployment of ...Transcendental meditation reduces congestive heart failure, new study shows
...of the outcomes is planned via a large multicenter trial with long-term follow-up. "This present finding is consistent with previous research demonstrating that the Transcendental Meditation program reduces factors that contribute to the cause or progression of heart failure, such as high blood pressure, s...Favorable outcomes from mild invitro fertilization practices
...echt, Netherlands) and colleagues did a randomised trial to compare mild IVF treatment with standard IVF treatment in 404 patients. The 1-year cumulative proportion of pregnancies leading to livebirths was much the same with a mild strategy of IVF (43.4%) as with the standard IVF strategy (44.7%). The prop...Insulating houses improves health and well-being
...n for improving health and well-being." This new trial emphasises the benefits of investing in housing, which are not limited to health, say researchers in an accompanying editorial. This evidence, and emerging evidence from other housing studies, should inform policies linking housing investment to impa...Garlic does not appear to lower cholesterol levels
... in the raw garlic group. "The results of this trial should not be generalized to other populations or health effects. Garlic might lower LDL in specific subpopulations, such as those with higher LDL concentrations, or may have other beneficial health effects," the authors write. "Based on our result...Positive results more likely from industry-funded breast cancer trials
...ical-company involvement on breast cancer clinical trial design and outcome. Drug-industry investment in research now exceeds the operating budget of the National Institutes of Health and previous studies have examined the impact on other areas of clinical medicine, but not breast cancer. Our study shine...Depression increases health risks in heart failure patients
...are currently enrolling patients in a new clinical trial to measure the effects of exercise and antidepressant medications on specific physiological indicators of heart disease. The trial, supported by the National Institutes of Health, has been dubbed UPBEAT -- short for "Understanding the Prognostic Bene...Is most published research really false?
...en should we accept early findings from a clinical trial indicating the benefits as true?). "Obtaining absolute 'truth' in research, say Djulbegovic and Hozo, "is impossible, and so society has to decide when less-than-perfect results may become acceptable."...Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows
...ed. The researchers are now considering a clinical trial to test whether the compound has a similar effect in humans with Down syndrome. "This treatment has remarkable potential," said Craig Garner, PhD, professor of psychiatry and behavioral sciences and co-director of Stanfords Down Syndrome Research C...Updated guidelines advise focusing on women's lifetime heart risk
...ze the importance of using well-conducted clinical trial data to develop national recommendations to help p... women in the Women's Health Initiative randomized trial of calcium plus vitamin D supplementation. The women were 50-79 years old. Half took 500mg calcium...Multislice CT speeds the diagnosis of chest pain in the emergency room
...to be determined." A large randomized controlled trial will put CT to a demanding test. Dubbed CT-STAT, t...c Triage of Acute Chest Pain Patients to Treatment trial will involve 750 low-risk patients evaluated for heart attack-like chest pain at 15 hospitals across...US Military Cancer Institute partners on cancer trial
...ed that they have entered into a Phase II clinical trial for a novel peptide vaccine for breast cancer. The...junction with USMCI's Clinical Trials Group. The trial will be a randomized, multi-center study among patients who have completed standard therapy for node...Slow-release morphine reduces level of intractable cough
...ocated for the suppression of cough, there are few trial data to support this recommendation. In fact, prio...interval, patients made three visits to a clinical trial center, where they filled out a quality-of-life questionnaire on the impact of chronic cough on acti...Drug reduces unscheduled trips to doctor for childhood asthma attacks
...r, randomized, double-blind and placebo-controlled trial appear in the second issue for February 2007 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society. Colin F. Robertson, M.D., of the Department of Respiratory Medicine at Royal Children's Hosp...Xylitol reduces risk of cavities
...on of lactic acid declined dramatically during the trial period. After four weeks, the proportion of caries-producing bacteria was down by a third, but six months afterward the values had returned to the original levels. Despite the relatively high dose of xylitol used, no negative effects were reported,...Gene expression test reveals ER and HER-2 status of breast tumors
...pond to hormonal therapy. A prospective clinical trial will soon open at M. D. Anderson to use these tests to recommend treatment for patients with newly diagnosed stage I-III breast cancer. In the Lancet Oncology paper, they employed an Affymetrix microarray to gather estrogen receptor and HER-2 rece...Benchmark fetal surgery study finds timeliness to be critical factor in success of treatment
...atients. The American investigators asked that the trial be stopped. Unbeknownst to investigators at that time, the trial oversight committee found significant differences between the two treatment modalities and recommend...Preclinical results of Geovax's AIDS vaccines demonstrate potential to protect against disease
...day reported successful results from a preclinical trial using GeoVax's vaccines for the therapeutic treatm...ny additional drug therapy. "The results of this trial demonstrate the long-term promise of our vaccines in treating HIV-AIDS," said Don Hildebrand, CEO of...New forecasting tool could reduce drug development costs
...venues by an average of $160 million per Phase III trial (from $347 to $507 million) during the drug's firs... last year (S3807) that would establish a clinical trial registry database that would report the results of later-stage clinical trials, both good and bad. ...Leading advocates express support for microbicide research, despite disappointing trial results
...India, South Africa, and Uganda. Another Phase III trial of CS sponsored by Family Health International was...nue their CS trials after findings from the CONRAD trial suggested that CS might be contributing to an increased risk of HIV infection. Although review of t...