Developments in tissue engineering offer new sources for stem cell treatments
...nical results of the first North American clinical trial using autologous muscle-derived stem cells to treat stress urinary incontinence. Using a needle biopsy technique, skeletal muscle tissue was harvested, stem cells isolated and expanded in vitro, and then implanted in patients using a transurethral ...Nationwide study compares surgeries to treat urinary incontinence in women
...ates has completed the largest randomized clinical trial to date comparing two commonly performed surgical procedures to treat urinary stress incontinence. Findings reveal that a procedure that places a sling to support the bladder is significantly more effective than another common technique, called th...Sling surgery is more effective than Burch for bladder control in women
In the largest and most rigorous U.S. trial comparing two traditional operations for stress ur...n was $12.4 billion in 1995. SISTEr is the first trial completed by UITN, with two other studies in the wings. Results of the second trial, the Behavior E...UPMC begins study of heart support device as a bridge to transplantation
... patients overall for the multi-center feasibility trial throughout nine centers in the United States. Five...the same effect. There is a parallel U.S. clinical trial that will look at the safety and feasibility of the VentrAssist LVAD as an alternative to transplant...A drug's brand name skews patient treatment choices
...t decisions by patients, according to a randomized trial of decision aids by researchers from McMaster University. The unexpected finding regarding the strong influence that drug names have on treatment choices emerged from a study undertaken by Dr. Anne Holbrook and McMaster colleagues who wanted to see...To get blood pressure under control, combination of medicines may be best
...so available separately as individual drugs. The trial randomly assigned patients to one of two drug combinations. Both combinations contained a drug called benazepril, which belongs to a class of medicines known as ACE inhibitors. The other drug in one of the combinations is a diuretic called hydrochlor...Clinical trial data for Perforomist Inhalation Solution presented at International ATS Conference
...-dummy, placebo- and active-controlled trial. The trial found that Perforomist Inhalation Solution, a twic...n my judgment, the results of the rigorous 12-week trial clearly demonstrate that physicians now have a new treatment option that is in accord with these GOL...Improving communication with families of dying patients reduces stress, anxiety and depression
... San Francisco on Monday, May 21. The multicenter trial found that family members who engaged in an average of 30 minutes of a family conference with the patients physician and received an in-depth bereavement booklet had a lower prevalence of post-traumatic stress syndrome after 90 days (44.6% compared w...Study finds 'wake up and breathe' strategy allows patients to come off ventilator sooner
...f Medicine in Nashville. The spontaneous awakening trial (SAT) allows them to wake up, so we can find out if they are ready to proceed without sedation. If the patient is uncomfortable, we restart sedation, but a lot of patients are comfortable enough to proceed with the next step in the protocol. This sec...Commonly used drug offers promise for premature babies
...eople, including pregnant women, making a clinical trial in people feasible. The researchers focused on a part of the brain known in developing infants as the germinal matrix, a temporary structure that is the birthplace of all brain cells in an infant. The structure runs like a jagged coastline just bel...UPMC performs first beating heart transplant procedure in the US
...ved TransMedics Inc. to begin the pilot phase of a trial of the investigational device exemption at five centers in the United States. In addition to UPMC, other centers participating include Brigham and Women's Hospital in Boston, the UCLA Medical Center in Los Angeles, the University of Chicago Hospitals...Children's Hospital and Pitt lead national trial of hypothermia to treat pediatric brain injury
...lion National Institutes of Health-funded clinical trial examining the effectiveness of induced hypothermia... coordinating site. A previous Phase II clinical trial of induced hypothermia therapy led by Dr. Adelson at Children's found that moderate hypothermia ther...Researchers begin randomized double-blind trial of airway bypass treatment for emphysema
... (undergoing only a bronchoscopy procedure). The trial is underway at 15 leading research institutions with more than 20 patients already randomized. At least 225 patients will be enrolled at up to 45 institutions during the next 12 to 18 months. Emphysema is a chronic, progressive, and irreversible ...Animal study leading to new treatments for hemorrhagic shock and uncontrolled abdominal hemorrhage
...s seeking regulatory approval to initiate a trauma trial in the United States. Dr. Manning indicates that this product shows promise as a life-saving treatment for severe injuries with major blood loss. The presentation is entitled Mesenteric Blood Flow During Hemoglobin-Based Oxygen Carrier (HBOC)-201 F...Infants with bronchiolitis may benefit more from albuterol
...Annual Meeting, a double-blind randomized clinical trial involving over 700 infants over a three year period showed a clear advantage for albuterol in successful discharges from the Emergency Department. Although many smaller studies have shown either no difference or an advantage to epinephrine, this s...ACE inhibitors help preserve kidney function in IgA nephropathy
...ldly elevated levels of protein in the urine. "Our trial focused on a subset of patients with a sort of 'pure' IgAN, without the confounding effects of aging or environmental toxic exposures, including smoking and alcohol, and without severe high blood pressure," says Dr. Coppo. After a median three year...Reducing cardiovascular disease risk factors when discontinuing hormone replacement therapy
...and Nutrition (WOMAN) study, a randomized clinical trial of CVD prevention. The focus of this investigation was 240 women who were taking HRT at baseline; 134 of these women were randomized to the lifestyle intervention and the remaining 106 were randomized to the health education group. Participants we...Low physical activity can improve fitness levels for sedentary, overweight postmenopausal women
...sical activity levels and fitness. "Although the trial by Church et al shows a linear dose-response relat...ably, because of cost and feasibility reasons, the trial mimicked only three physical activity patterns that can occur; in real life, there are infinitely mo...Vitamin D supplements may offer cheap and effective immune system boost against TB
... The researchers performed a randomised control trial on a group of volunteers who were given either a 2.5mg supplement or a placebo. Samples of the volunteers' blood were then tested in Dr Robert Wilkinson's Wellcome Trust-funded laboratory at Imperial College, to see whether the supplement affected th...San Francisco VA researcher receives top Veterans Affairs award
...ing Initiative, a nationwide, multicenter clinical trial designed to establish a brain biomarker for Alzheimer's disease. He is also the principal investigator of the SFVAMC Neuroscience Center of Excellence, a research collaboration between the VA, the Department of Defense, and the Northern California I...