New research disproves belief that group psychotherapy extends the lives of cancer patients
...d to psychotherapy. In biomedicine, a large-scale trial would not be considered warranted for cases in which a hypothesis was interesting but improbable given the available data. Therefore, the authors conclude that there is not enough basis to justify investing additional funding for research in this ar...Promising drug fails to improve COPD symptoms
...f the randomized, double-blind, placebo-controlled trial of infliximab were published in the first issue of... negative results," make in unlikely that a longer trial will be undertaken, according to the accompanying editorial. ...First clinical trial of gene therapy for childhood blindness
The first clinical trial to test a revolutionary treatment for blindness in...pact on future treatments for eye disease. The trial involves adults and children who have a condition called Lebers congenital amaurosis (LCA), which is...Topical testosterone cream does not increase sexual drive in female cancer survivors
...ebo, according to a randomized controlled clinical trial in the May 2 Journal of the National Cancer Insti...lleagues conducted a randomized phase III clinical trial to determine whether testosterone treatment improved libido in 150 postmenopausal cancer survivors. ...Heart failure medication does not improve survival, compared to more widely used medication
...sire AP-HP, Paris, and colleagues with the SURVIVE trial (Survival of Patients With Acute Heart Failure in ...ducted a study in which the primary purpose of the trial was to assess long-term survival outcomes for 1,327 ADHF patients who received levosimendan or dobut...Other highlights in the May 2 JNCI
...fen Trial. The initial findings from the Italian trial showed no significant reduction in breast cancer risk with tamoxifen use. However, the National Surgical Adjuvant Breast and Bowel Projects Breast Cancer Prevention Trial found that tamoxifen reduced the risk of estrogen receptor-positive breast canc...Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
...he authors write. "The changes are consistent with trial evidence and national and international guidelines. The risk profile for patients with STEMI has not changed significantly over this interval, whereas the risk for patients with NSTE ACS has increased slightly. For the first time, we have demonstrate...New data shows once a day LAMICTAL XR is effective in patients with partial epilepsy
...tal XR and ABOUT THE COMPASS STUDY The second trial (COMPASS) compared the pharmacokinetics of twice daily, immediate release Lamictal to once daily Lamictal XR in patients thirteen years of age and older with epilepsy. The open label, conversion study consisted of a 2 week base line phase with Lamic...Acrux completes enrollment in key phase 2 trial
...letedenrolment of 40 patients in the final Phase 2 trial of its unique testosteronelotion for treatment of ...erone deficiency in men. Preliminary resultsof the trial are expected to be available in July 2007. The trial is being conducted at 8 clinics in the USA. The...Resistant HIV quickly hides in infants' cells
... of age enrolled in a large, multi-center clinical trial covering 10 states. Their results showed that five of 21 HIV-positive infants were infected with drug-resistant HIV transmitted from their mothersa surprisingly high figure. Of those five, four were resistant to non-nucleoside reverse transcriptas...Free weight training gets workers with rotator cuff injuries back on the job
...now hope to test the model in a larger prospective trial of workers at varying levels of injury in order to demonstrate increased outcome efficacy with a standardized prescription and concurrently measure cost-benefit to the worker's compensation system....New blood test can diagnose and monitor treatment of Parkinson's disease
...lay the disease. "The test will also ensure drug trial participants actually have PD so research outcomes will be statistically more valid, which paves the way for faster and more effective drug development. "When drugs that modify disease progression are available, this test may also help in showing w...Increasing survival of organ transplant patients by reducing time interval for transported organs
...S to assess organ function was also discussed. The trial sites participating in the PROTECT I study include...e pilot phase of the PROCEED multi-center clinical trial in the U.S. to evaluate the safety and performance of the OCS for heart transplants. The PROCEED tr...Dopamine-related drugs affect reward-seeking behavior
...win" more money, participants had to learn through trial and error which symbols resulted in which outcomes. The study found people who took levodopa were 95 percent more likely to choose symbols associated with higher monetary gains than those who took haloperidol. As a result, the levodopa group won mo...Are higher doses of cholesterol drugs worth the extra money? Only sometimes, study says
...illustrates that simply having a positive clinical trial may not be as informative as reporting what the ac...o, for the new study, the team pooled the clinical trial data from all patients with a history of ACS, and in a separate pool, all patients with CAD. They lo...Clinical trial coordinators need more financial conflict-of-interest training
... Their study found that 41 percent of the clinical trial coordinators surveyed had experience disclosing financial aspects of the trial to potential participants, and 28 percent of the coordinators had been asked by participants about p...Head and neck cancer vaccine targets proteins to create immune response
...he vaccine has been determined, a phase I clinical trial of the vaccine has begun at the University of Pittsburgh Cancer Institute to assess its safety in head and neck cancer patients. Head and neck cancer accounts for about 5 percent of all newly diagnosed cancers in the United States. More than two-...Research could lead to treatment for Alzheimer's disease
... molecules and bypass the usual lengthy process of trial and error in molecule design. Within a year we had...of clinical trials this year and begin the lengthy trial process necessary before the FDA approves a drug to be available on the market. Alzheimer's diseas...Rhode Island Hospital study identifies high-risk patient populations for MRSA carriage
...ally high risk of MRSA carriage. In addition, this trial is the first to look at the quantity of MRSA in the nares (openings of the nasal cavities) of different patient populations. Currently, the standard method to detect carriage of MRSA is by routine culture whereby results can take several days. Del...... shown promise in preliminary data from a clinical trial at the University of California, San Francisco. ...s made from the patients own tumor. The clinical trial was conducted by the UCSF Brain Tumor Research Center. Results were presented today (April 16) at th...