Clinical studies evaluate potential treatments for mouth ulcers
...agues conducted a 60-day, randomized, double-blind trial in 26 individuals (average age 33) with recurrent ... Nice, France, conducted a double-blind randomized trial of 1 percent pimecrolimus cream for the treatment of oral erosive lichen planus. Six patients recei...Tip sheet Annals of Internal Medicine, April 17, 2007
... Therapy For Helicobacter Pylori In a clinical trial testing two different ways to treat Helicobacter pylori infection (a common cause of stomach ulcers), researchers found that four antibiotics given sequentially cured the infection more often than standard treatment with three antibiotics taken toget...Study finds drug helps PTSD nightmares
...ril 15 in Biological Psychiatry. The randomized trial of 40 veterans compared a nightly dose of prazosin...mg at bedtime. The average dose of prazosin in the trial was 13.3 mg. By comparison, typical prazosin doses for controlling blood pressure or treating prosta...MacroChem completes patient enrollment for Phase II trial of EcoNail for treatment of onychomycosis
...valuate 24-week interim data later this year. This trial was specifically designed, with the assistance of well-known onychomycosis experts, to address three important objectives: to assess early signs of efficacy, to maintain robust clinical endpoints in the full study, and, if successful, to facilitate a...Use of hydrocortisone reduces incidence of atrial fibrillation after cardiac surgery
... and colleagues conducted a randomized multicenter trial to test whether intravenous corticosteroid administration prevents AF after cardiac surgery. The study, conducted at three university hospitals in Finland, included 241 patients without prior AF who were scheduled to undergo CABG surgery, aortic valv...Experimental flu vaccine appears promising in early tests
... by a recombinant baculovirus (rHA0). The clinical trial was conducted at three U.S. academic medical centers during the 2004-2005 influenza season and included 460 healthy adults. Participants were randomly assigned to receive a single injection of saline placebo (n = 154); 75 g of an rHA0 vaccine contain...Tai Chi boosts immunity to shingles virus in older adults, NIH-sponsored study reports
... (NIH)-funded study is the first rigorous clinical trial to suggest that a behavioral intervention, alone o...ing Branch. The randomized, controlled clinical trial included 112 healthy adults ages 59 to 86 (average age of 70). Each person took part in a 16-week pr...New drug shows promise for treating epileptic seizures
...eatments can involve several doses per day. The trial was conducted across 19 locations in five European countries: Croatia, The Czech Republic, Germany, Lithuania and Poland. Patients with at least four partial-onset seizures per month, in spite of treatment with other medications, were administered ES...Opportunistic chlamydia screening 'not underpinned by sound evidence'
... implemented by 2008. Yet no randomised controlled trial has shown that this type of screening programme reduces long term illness. Furthermore, most studies showing that chlamydia screening is cost effective do not satisfy accepted quality criteria for economic evaluations, says the author. They also te...Approval to start US BTT pivotal trial
...the world's largest healthcare market. "The BTT trial shares the same protocol as the Feasibility Trial....olled in the BTT trial. "The VentrAssist US BTT trial will involve up to 140 patients at leading heart transplant hospitals in America. "The aim of the ...Northwestern chemists develop new method for synthesizing anti-cancer flavonoids
...ient; the mirror image does nothing.) After much trial and error in the lab, Scheidt and his colleagues hit upon a catalyst that, when added to other simple materials, produced a complex one-handed molecule like the flavonoids found in nature, with the core structure intact. (They tested 30 to 40 catalys...Study sheds light on medication treatment options for bipolar disorder
...polar Disorder (STEP-BD), a $26.8 million clinical trial funded by the National Institutes of Health's Nati...ve broader applicability than a tightly controlled trial in which people are excluded from participating if they have co-existing disorders. Before partici...MRI detects most missed opposite breast cancers in women
...n the opposite breast. Results of a major clinical trial show that magnetic resonance imaging (MRI) scans a...id Constantine Gatsonis, lead statistician for the trial and director of the Center for Statistical Sciences at Brown University. "If my wife were diagnosed ...Stem cells speed growth of healthy liver tissue
...are currently embarking on a randomized controlled trial of the therapy. ...Novel anti-oxidant and anti-inflammatory agent shows effectiveness on key endpoints in trial
...eakthroughs in cardiovascular medicine. While the trial results did not demonstrate a difference with the ...reduction of 64 % (p 2 2 2 ALPHA Trial The trial was entitled Effects of the Novel Anti-Oxidant and Anti-Inflammatory Agent Succinobucol (AGI-1067) o...Patient adherence for successful tuberculosis treatment
...s of this action, a randomized controlled clinical trial was run between June 2003 and January 2005 on 16 d...ria. Research work is continuing, in the form of a trial conducted by the IRD in conjunction with WHO, aiming to make available a shorter, 4-month treatment ...Study finds coronary procedure adds no benefit over 'optimal medical therapy' alone
...help prevent scarring, were not approved until the trial was nearly completed, only 31 COURAGE patients received this type of stent. But studies have shown little difference between coated and non-coated stents in their ability to prevent heart attacks and deaths. At a median follow-up of almost five y...Implant device effectively maintains heart function for transplant-listed patients
...r years at a time. In a prospective, multi-center trial conducted at 26 sites in the US, 133 patients listed for heart transplantation and refractory to intravenous inotropic therapy, received a HeartMate II, which was then evaluated for safety and overall efficacy based on historical LVAD performance cri...Disease management programs improve long-term outcomes
... management of heart failure. In this randomized trial conducted between October 5, 1999 and January 18, ...f days of each hospitalization. According to the trial results, patients who were involved in the disease management program spent an average of nine fewer...EVEREST data on use of tolvaptan published in JAMA and featured at ACC
...d long-term analyses of the international landmark trial Efficacy of Vasopressin antagonism in Heart Failur...s, represents three studies: a long-term outcomes trial evaluating patients after their discharge for a minimum of 60 days of treatment, and two identical, ...