Light-based probe 'sees' early cancers in first tests on human tissue
...x said. His team plans to begin a small clinical trial of the advanced endoscope in collaboration with researchers at Duke University Medical Center. The team also is conducting animal studies to test the feasibility of incorporating fa/LCI into instruments for examining the colon, lung and other organs....Long-term aspirin use associated with reduced risk of dying in women
...r or not to take aspirin, as opposed to a clinical trial where women are randomly assigned to aspirin or a placebo, the results do not suggest that all women should take aspirin. "Nevertheless, these data support a need for continued investigation of the use of aspirin for chronic disease prevention," the...Pairing medical therapy with coronary intervention fails to reduce heart disease deaths
...arization and Aggressive DruG Evaluation (COURAGE) trial enrolled 2,287 patients at 50 hospitals in the Uni...t of Veterans Affairs. "But results of the COURAGE trial demonstrate that two treatments are not always better than one. These findings, along with data from...Studies highlight advances in diagnosis, medical therapy
...n and Urgent Intervention Triage Strategy (ACUITY) trial suggest that bivalirudin may become an increasingl...restore full blood flow to the heart. The ACUITY trial recruited 13,819 patients with moderate-to-high-risk acute coronary syndromes from 450 medical cente...Studies highlight 'real world' use, safety of drug-eluting stents
...at Careggi Hospital, Florence, Italy. "The RECLOSE trial is the first prospective clinical trial that has shown an increased risk of thrombosis in drug-eluting stents in patients who are nonrespond...Drug does not reduce risk of death for heart attack patients with refractory shock
...dy in Unstable MI Patients With Cardiogenic Shock) trial investigators tested the effect of NOS inhibition with the drug tilarginine on risk of death on heart attack patients with cardiogenic shock. The study included 398 patients at 130 centers in eight countries. Participants were enrolled between Januar...Place more than race tied to heart disease risk
... rural Caucasians. The data come from a clinical trial investigating whether Internet-based telemedicine can decrease cardiovascular disease risk in underserved inner-city and rural populations. The final results of the study, which is being conducted at Temple University in Philadelphia and Geisinger Me...Drug/intervention combinations offer benefit in severe CVD
...ooked positive, but the use of TAI in this largest trial of cardiogenic shock patients ever conducted showe... time would improve clinical outcomes. The ECLIPSE trial (Evaluation of CLevidipine In the Postoperative Treatment of Hypertension Assessing Safety Events), ...Community and clinic-based HIV-1 control program fails to decrease incidence of HIV-1 in Zimbabwe
A trial in Zimbabwe has shown that a programme of integrat...IDS open days at health centers. This was a large trial with more than 63,000 meetings being conducted and 7 million condoms distributed by trained peer edu...Colon cancer survival linked to number of lymph nodes examined
...ne of the 17 studies examined, a national clinical trial enrolling more than 3,200 patients to look at the ... be supported by a randomized, controlled clinical trial - which would not be ethically possible to do....NSW Premier announces $15M for children's cancer research
...of childhoodcancers including the first paediatric trial in Australia that uses genetic testing to tailorchemotherapy regimes for children being treated with leukaemia. "This method of taking discovery at the laboratory bench to the bedside in a rapid manner is animportant principle for us as we know that ...LIALDA -- the first oral once-daily mesalamine for ulcerative colitis -- now available
...ly on my mind," said Becky Pace, a LIALDA clinical trial patient. "I could not believe taking medication once a day would help as much as it did. LIALDA brought my disease into remission." About LIALDA LIALDA is part of a drug class called aminosalicylates, which contain 5-aminosalicyclic acid (5-ASA)...NIH names Clinical Trial Units for the Microbicide Trials Network
...l Institutes of Health (NIH), as HIV/AIDS clinical trial units (CTUs) for the Microbicide Trials Network (M...equires an aggressive agenda in which the clinical trial units and clinical research sites play an essential role. By virtue of being selected by NIH, our CT...UW launches study testing adult stem cells for heart damage repair
...ers in the country taking part in a novel clinical trial investigating if a subject's own stem cells can tr...ed his own stem cells or a placebo substance. This trial is the first human Phase II adult stem cell therapy study in the U.S. Its goal is to investigate the...Many Americans at high risk of vision loss do not have access to eye care
...authors conclude. In another report of a clinical trial involving 22,071 healthy U.S. male physicians age ...ston, and colleagues analyzed data from a clinical trial in which about half the men were randomly assigned to take 50 milligrams of beta carotene every othe...New study: Pine bark significantly reduces endometriosis
..." said Dr. Kohama. "In addition, five women in the trial taking Pycnogenol actually got pregnant," he said. When Gn-RHa is used continuously for more than two weeks, the production of oestrogen stops, depriving the endometrial implants of oestrogen, causing them to become inactive and degenerate. Most w...Probe to detect spread of breast cancer co-developed by UH scientist
...as approved the detection procedure for a clinical trial of women undergoing breast cancer surgery at Unive...and is a senior lecturer at UCL, is overseeing the trial and used the probe for the first time in surgery in December. Douek, who visited Houston recently i...Both minor and major ECG abnormalities linked with increased risk of cardiovascular events in women
...s combination would reduce CHD and CVD events. The trial found that there was a significant increase in CHD rates among women taking hormone therapy compared with the placebo group. The sample analyzed included 14,749 postmenopausal asymptomatic women with intact uterus who received 1 daily tablet contai...PET imaging identifies aggressive kidney cancers that require surgery
...his work represents the first prospective clinical trial to determine whether PET using a radiolabeled anti...od of recurrence. "The promising results of this trial have stimulated interest in a larger, prospective multi-center trial to confirm our findings, and ul......egulations governing public disclosure of clinical trial data submitted to the Food and Drug Administration...ntly, pharmaceutical manufacturers submit clinical trial data, which establish the safety and efficacy of their products, to the FDA as part of the drug appl...