Under-diagnosed rage disorder more prevalent than previously thought
...pful because they work to teach people to identify triggers that set off attacks of rage, says Fava, who is al...ogram. These programs can teach people to identify triggers that set off attacks of rage. "The study clearly shows that we have a problem of low early outreach ...New mechanism explains glucose effect on wakefulness
...c survival mechanisms is the neural machinery that triggers the hungry brain to the alertness needed for seeking food. That same machinery swings the other way after a hearty meal, as exemplified by the long and honored custom of the siesta. However, scientists have understood little about how the basic energ...Stress, alcoholics, and post-traumatic stress disorder
...duals with PTSD and other psychiatric comorbidity, triggers for relapse and biologic vulnerabilities to relapse may be different than for individuals without psychiatric comorbidity. We plan to investigate the impact of stress-management techniques as well as medications that impact the stress response on cr...New treatment for food poisoning
...uses the food-borne disease, listeriosis. It often triggers a brain infection and kills up to 30% of those affected. To test whether antibiotics are effective, bacteria are taken from patients and tested in the laboratory. These tests measure whether antibiotics can halt the growth of Listeria in laboratory ...H5N1 threat puts human flu back in spotlight
...led antigenic drift. An antigen is a molecule that triggers an immune system attack. In contrast, an antigenic shift occurs when different viruses infect the same animal and exchange genes. In 1957, a human H1N1 and avian H2N2 infected the same animal and swapped some genes--a process called reassortment. T...T cell 'brakes' lost during human evolution
...signaling from the T cell receptor, which normally triggers the response of T cells in the immune system. "Siglecs are like 'brakes' that can slow down the activation of an immune cell upon stimulation," said Ajit Varki, M.D., UCSD Professor of Medicine and Cellular and Molecular Medicine and co-director of...Immune culprit in malaria-associated anemia
... produced by immune cells during malaria infection triggers severe anemia, a lethal complication of the disease. Richard Bucala and colleagues at Yale University (New Haven, CT) show that immune cells in mice with malaria secrete a protein called MIF, which decreases the production of red blood cells (RBCs) f...Study first to show potential of light-activated gene therapy for knee injuries
...elength UV light is not absorbed by DNA, but still triggers the same natural SOS system. Instead of triggering the system by directly causing dangerous mutations like short wavelength UV light, the longer wavelength creates molecules called free radicals. Free radicals are highly reactive molecules that can t...St. Jude unlocks mystery of very aggressive leukemia
...the tumor suppressor gene Arf in bone marrow cells triggers an aggressive form of ALL. Inactivation of both Ar... to receptors on the surface of lymphocytes, which triggers the activity of the JAK kinases. The activated JAK kinases then stimulate cell growth through a sign...Agent protects Parkinson's neurons from rotenone toxicity
...otropic glutamate receptors by drugs such as L-AP4 triggers a chain of events that leads to microtubule stabilization. This cascade, called the MAP kinase pathway, activates several enzymes that regulate the stability of microtubules. The primary symptoms of Parkinson's disease are tremors, slowness in mov...Acrux granted first grant in Europe, triggering payment from Lilly
...hting the significance of this patent, thedecision triggers a payment of AUS$0.5 million from Elanco, the animal health division of the major US pharmaceutical company Eli Lilly and Company, which has licensed Acrux's technology for the development and commercialisation of multiple animal health products worl...Technique could speed new medulloblastoma drugs
...work by blocking individual molecules that are key triggers of disease. This St. Jude study is important beca...idual children which biochemical signaling pathway triggers and sustains the cancer by identifying key genes that are linked to that pathway. The investigators ...Lizard 'third eye' sheds light on evolution of color vision
...zard's third eye sees blue light, the blue pigment triggers a molecule called gustducin, which is very similar...rd's third eye sees green light, the green pigment triggers a different molecule called Go, known as "G-other," which also signals light responses in the light-...JCI table of contents, April 6, 2006
...: The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells AUT...6958 IMMUNOLOGY Forget me not: chronic infection triggers autoimmune disease Early childhood infections are hypothesized to predispose susceptible individual...Cystic fibrosis research could benefit from multi-functional sensing tool
...g in vitro studies. "Before you can identify what triggers the ATP release, we must be able to quantitatively measure the released species at the cell surface," Mizaikoff said, noting that many pathological events involve the disruption of chemical communication and molecular signaling between cells, especia...Reduced insulin in the brain triggers Alzheimer's degeneration
...e demonstrated that a loss of insulin in the brain triggers the onset of Alzheimer's, probably because as the ...beta. This kinase is overactive in Alzheimer's and triggers tau phosphorylation, which is known to be at the core of neurofibrillary tangles. The researchers ha...Global program to eliminate elephantiasis has early success in Egypt
...n where the worms lodge in lymphatic vessels. This triggers inflammation that blocks the drainage normally provided by the lymphatic system and leads to massive swelling of the legs, known as elephantiasis, and genital deformities, which are called hydroceles. "In addition to causing disability, the disfigur...Scientists use PET scans to monitor lung inflammation noninvasively
... "Endotoxin is a purified bacterial substance that triggers inflammation," Schuster says. "The technique we used keeps that inflammation compartmentalized to a small region in the lung, ensuring that the inflammation doesn't become systemic." Another research group previously had shown that this artificial in...UCI researchers identify first compound to block progression of Alzheimer's disease
...t is the buildup of beta-amyloid in the brain that triggers the development of Alzheimer's in people.......at bits of the brain are lighting up but also what triggers it to light up and when. In this test, the important thing was to find out whether brain activity before an event has an impact on memory or whether, as was previously thought, it's just brain activity after an event that is important for memory. Wi...