Case study: cross-cultural bioethics training program helps fight African 'brain drain'
...f Bioethics and the programs director. But it also turns out that our trainees are making institutional changes to policies, drafting new guidelines, and generally raising awareness of the need to support research ethics. And some trainees are not just doing these things in their home countries, but throug...'Cars' imaging reveals clues to myelin damage
...tained in the myelin. Cutting off one of the tails turns the lipid molecules into LPC, amplifying the effect and further degrading the myelin. The research was carried out in spinal cord tissues extracted from animals and in the sciatic nerves of living mice. Findings were confirmed by comparing CARS r...Progress toward an antitumor vaccine
... very easy to accomplish with polysaccharides, but turns out to be very complicated with glycoproteins, because the protein portion of the molecule has many reactive groups that are attacked in the coupling reaction. In addition, says Kunz, many of the structures that make suitable anchors are themselves h...Low-carb diets' effects linked to rise in newly identified 'starvation hormone'
...s with adipose tissue to send fat to the liver. It turns on the metabolism of fat into ketone bodiesand at the same time, it sensitizes the animals to going into torpor to conserve energy. Its clear that FGF21 is a principal component of the fasting or starvation response." The two studies together lead ...Tony Hunter receives Robert. J. and Claire Pasarow Award for Cancer Research
...or his key discoveries of the chemical switch that turns healthy cells into cancer cells. The annual Pasa...otein molecule - is a common way in which the body turns on or off proteins such as enzymes. Thus, phosphorylation of proteins in cells, which is often trigg...Medical management of another condition may not lead to early cancer diagnosis
...t Duke and lead investigator on the study. "But it turns out that was not the case." Zafar will present the results of the study in a poster presentation at the American Society of Clinical Oncology annual meeting in Chicago on Saturday, June 2. The study was funded by the U.S. Department of Veterans Aff......lly live is around 1,000 to 1,100 days. If NDGA turns out to extend maximal lifespan by 20 or 30 percent...g could emerge, Miller says. Even if this agent turns out to be good for mice, it wont be possible to tell without careful studies of humans whether NDGA ...Scripps Research awarded $17 million for adult stem cell use to treat eye diseases
... system (CNS) called glia," adds Friedlander. "It turns out that most neovascular eye diseases have an associated gliosis (proliferation of glial cells) and we can exploit this affinity by targeting the injected cells to these sites. Glioblastoma multiforme, a highly malignant brain tumor, is another CNS ...Anxiety hikes risk of heart attack, death
...e. If you give people this type of reassurance, it turns a frightening disease into something they can grow old with," Dr. Blatt said. James L. Januzzi, M.D., F.A.C.C., agreed. "This study provides further insight into the complex connections between the brain and heart," said Dr. Januzzi, an associate p...Stanford researchers identify immune dysfunction in melanoma patients
...react properly to interferon. If Lee's suspicion turns out to be true, doctors may be able to screen melanoma patients for interferon response and provide prolonged interferon treatment for only those patients whose immune cells have defects in that pathway. That means patients who wouldn't benefit from ...Scientists find missing link to understand how plants make vitamin C
...three steps, like a curving driveway, require some turns but no real choices and no backing-up. Through efforts led by UCLA postdoctoral fellow Dr. Carole Linster, the plant VTC2 enzyme was expressed and purified from bacteria. After preparing their own GDP-L-galactose, the team showed that VTC2 is re...Anti-fungal drug stops blood vessel growth
...e life forms to become fragile and break apart. It turns out that itraconazole can block the same enzyme in blood vessels, but the researchers arent positive if thats the reason blood vessels stop growing, because related antifungal drugs had much lower inhibitory effect. Our screening test did show tha...Decision making by the growing elderly population is uncharted territory
...ct a persons ability to make sound decisions? It turns out that it depends on the situation. In some decisions, thinking harder about unfamiliar information will produce the best decisions, and older adults are likely to fare less well, says Ellen Peters, courtesy professor of psychology at the Universit...OHSU surgeon implants donated tissue allografts
...d a specialist in sports medicine. "Oregonians, it turns out, are among the most beneficent with respect to providing their bodies to organ donation programs in the entire country." Until recently, however, it was difficult to access some of these tissues for transplantation. Now, as a result of a new co...Listen to your heart: Researchers discover a physiological indicator of vulnerability to temptation
...s healthy snack of cookies and candy. HRV as it turns out was considerably higher when people were working to resist temptation (eating carrots rather than cookies and chocolate) than when they were not, suggesting that HRV was mirroring the self regulation taking place. In part two of the experiment,...Genetic pathways to curable and incurable forms of pancreatic cancer identified
...ange shape and become more mobile and invasive. It turns out that the cystic pancreatic cancer cells are resistant to these effects of TGFb and these types of cancers are also less likely to invade surrounding tissues and to metastasize, or spread, to other organs. These properties likely contribute to the...RNAi shows promise in gene therapy, Stanford researcher says
...ctively destroyed. When used as gene therapy, RNAi turns off genes that are overactive in such diseases as ...time. "However, the detriment of RNAi gene therapy turns out to be that it uses the body's own machinery." He said he expects the current trials will help hi...Benchmark fetal surgery study finds timeliness to be critical factor in success of treatment
... and recipient twins. How is this possible? "It turns out that in amnioreduction, there were significant numbers of treatment failures, so patients were dropping out in the amnioreduction arm because they were failing therapy, whereas they were dying in the laser therapy," says Dr. Crombleholme. Statis...Mimicking how the brain recognizes street scenes
...tions. "The versatility of the biological model turns computer vision from a trick into something really useful," said co-author Stanley Bileschi, a post-doctoral researcher in the Poggio lab. He and co-author Lior Wolf, a former post-doctoral associate who is now on the faculty of the Computer Science ...Risk for stroke, death not higher for sickle cell children with early complications
...e a genetic error in their hemoglobin. The disease turns the usually soft, round red blood cell that carries oxygen through the body into an inflexible, sickle-shaped cell that causes blockages in blood vessels and prevents body tissues from receiving oxygen. It is estimated that at least 70,000 Americans ...