First diagnostic indicator for Amytrophic Lateral Sclerosis (ALS) identified
...rgo months of diagnostic evaluation and remove the uncertainty that currently lingers with physicians and patients even after a diagnosis is made."...Have targets improved performance in the English NHS?
...gets with sanctions? They suggest introducing more uncertainty in the way that performance is assessed and better auditing of performance data. They also call for an independent body to investigate the genuineness of reported improvements and the costs to other services. Although these changes would not wholly e...Warning of risk to breast cancer patients from vaginal oestrogen
...aid that in the UK and the USA there was currently uncertainty among cancer specialists and other doctors, including gynaecologists, about the safety of preparations such as Vagifem for women receiving AIs, and they are widely used. Some doctors do measure serum oestradiol, but most assays are not sensitive enou...Screening for prostate cancer may not reduce men's risk of death
...asymptomatic men to reduce mortality. Rather, the uncertainty of screening should be explained to patients in a process of 'verbal informed consent,' promoting informed decision making."......otential to provide a substantial reduction in the uncertainty currently seen in cancer diagnosis, once further work has been carried out to standardize and expand this methodology....Hopkins researcher links gene mutation with poor outcomes in people with most common thyroid cancer
...ad of disease. However, these criteria often leave uncertainty regarding the risk of tumor progression and recurrence. "What we have is a novel molecular diagnostic tool that will improve existing clinical efforts," Xing said.The study patients were recruited from The Johns Hopkins University School of Medicine;...New method for examining cost-effectiveness of new drugs for chronic illnesses
...ether within a decision model, and to quantify the uncertainty associated with cost effectiveness. Comparing different drugs for epilepsy has been difficult because there are few head-to-head trials of different agents, and because the observed rates of patient withdrawal from the drugs change over time. The i...Failure to resolve budget reconciliation leaves patients and doctors uncertain
...t for Medicare reimbursement. The effects of this uncertainty go well beyond the amounts that physicians are pai...iate their good intentions. Yet we are faced with uncertainty and confusion, instead of the decisive action in Washington that our patients require." "We als...Mayo Clinic finds kidney cancer patients are unlikely to respond to potential treatment drug
...treat this and other cancers, and to alleviate the uncertainty that accompanies a cancer diagnosis by finding better ways to individualize treatment plans. This study's purpose was to determine the frequency of KIT (a receptor kinase tyrosine) expression and mutation in aggressive kidney tumors. The goal was to...Lowering blood pressure more important than drug class in preventing kidney disease
...in diabetes on the basis of efficacy, and residual uncertainty still exists about the inherent value of these drugs in other renal disorders. In view of the present analysis, treatment decisions for hypertension in renal disease should be based on the blood-pressure-lowering effect, comparative tolerability, and...Higher dose formulation of FOSRENOL approved to reduce serum phosphorus in esrd patients
...not limited to: risks associated with the inherent uncertainty of pharmaceutical research, product development, manufacturing and commercialization; the impact of competitive products, including, but not limited to, the impact of those on Shire plc's Attention Deficit and Hyperactivity Disorder ("ADHD") franchis...Pain research using electronic diaries helps identify who responds to 'placebo effect'
...rticipants recorded the data, removing some of the uncertainty and inaccuracy that often accompanied pencil-and-paper diaries. Fibromyalgia is a common condition that affects 2 to 4 percent of the U.S. population and is more commonly diagnosed in women. Clauw and his colleagues at the Chronic Pain and Fatigue R...ERS altimeter survey shows growth of Greenland Ice Sheet interior
...as well as ice fields which can be used to reduce uncertainty about whether land ice sheets are growing or shrinking as concern grows about the effects of global warming. The ice sheet covering Earth's largest island of Greenland has an area of 1 833 900 square kilometres and an average thickness of 2.3 kilome...Decline in breast cancer deaths explained by use of screening and adjuvant therapies
...th a median of 15 percent), reflecting the greater uncertainty associated with estimating the benefit of screenin...erning their point estimates and with the level of uncertainty reflected in their overall conclusions. In his opinion, "the evidence makes clear that the benefit o...Fish is good fish is bad. Balancing health risks and benefits
...ize disparate information and assess the impact of uncertainty on our conclusions." In "A Quantitative Analysis of Fish Consumption and Stroke Risk" by Colleen Bouzan, MS, Joshua T. Cohen, PhD, William E. Connor, MD, Penny M. Kris-Etherton, PhD, George M. Gray, PhD, Ariane Knig, PhD, Robert S. Lawrence, MD, Davi...Many cancer survivors initiate lifestyle changes to benefit their health
...aints, competing treatment or health concerns, and uncertainty regarding the delivery of health behavior messages and their potential impact on a patient's outcome. An accompanying editorial by Patricia A. Ganz, MD, of the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, and co-c...FDA expands indication for ADDERALL XR (CII) confirming safety and efficacy in adolescents
...not limited to, risks associated with the inherent uncertainty of pharmaceutical research, product development, manufacturing and commercialization, the impact of competitive products, including, but not limited to, the impact of those on Shire's ADHD franchise, patents, including but not limited to, legal chall...Single dose of chemotherapy is as effective as radiotherapy for testicular cancer
...finally establishes after 20 years of research and uncertainty that it is safe to risk less treatment in these patients. We found that one dose of carboplatin in the short term is as safe as radiation and is less toxic. Patients assigned to chemotherapy also had fewer seminomas occurring in the remaining testis ...The Cochrane Library newsletter, 2005, issue 3
... advanced breast cancer. There was still, however, uncertainty about the best time to start giving these drugs. "Our research confirms the general feeling that bisphosphonates are important in reducing bone complications in women with breast cancer and bone involvement" says lead author Nick Pavlakis who works i...Experts discuss use of human stem cells in ape and monkey brains
...y or morally," she adds. "Debate is complicated by uncertainty and uncharted territory in all of our fields of expertise. It quickly became clear how little is known." "Many of us expected that, once we'd pooled our expertise, we'd be able to say why human cells would not produce significant changes in non-huma...