W.M. Keck Foundation announces 2007 class of Distinguished Young Scholars in medical research
...nd normal cells, the research has the potential to uncover defects in chromosome regulation that cause malignancy, which may lead to advances in combating cancerous cells in the body. Wallace Marshall, Ph.D., Department of Biochemistry, University of California, San Francisco Dr Marshall investigates ho...Investigating the causes of Parkinson's disease
... model of Parkinsons will be crucial in helping to uncover and study why nerve cells die in the region of the brain affected in Parkinsons disease. At Nottingham we have an excellent team who are committed to understanding this model. I look forward to driving this interesting new avenue of research and in...Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders
...e sequencing of the human genome are being used to uncover new strategies for treating genetic human disease, said NHGRI Director Francis S. Collins, M.D., Ph.D. This work also underscores the value of animal models in learning more about the pathways involved in human disease and how to target therapies tha...HIV and malaria combine to adversely affect pregnant women and their infants
...s them as susceptible as first-time mothers. To uncover how HIV affects PAM, Kain and his team collected samples from women in the first pregnancy as well as from women in their subsequent ones living in the Kenyan region where malaria is common. The researchers demonstrated that protection to PAM is medi...Anti-dandruff compound may help fight epilepsy
...rmal nerve cell activity. Most drug discoveries uncover chemicals that stop things from working - its a lot easier to close or block a door than open it, Li says. But here we found a chemical that makes a defective protein work better. So now we have a chance to actually try to fix the causes of epilepsy,...Researchers hot on the trail of brain cell degeneration
.... It is more than likely that future research will uncover more such factors interacting with each other. Investigating these will benefit new forms of treatment and advance research that aims to alleviate symptoms. The researchers behind the study hope that the results can be used in planning new targets fo...Men with no sons more at risk for prostate cancer, according to Mailman School of PH Study
...mprints Center -- in which epidemiologists seek to uncover the causes of a broad range of disease and health outcomes, by following individuals from an early point in life and examining their risks for disease. Life course studies are particularly well positioned to examine the interplay of genetic and envir...Research offers hope for alcoholics
...iggers in the brain, so further investigations may uncover drug targets in the Orexin system to treat both conditions," Dr Lawrence said. The Florey scientists are now conducting multiple experiments to discover the precise circumstances that activate the Orexin system. "To explore this discovery further...Consortium of international hospitals receives $11 million to conduct study of genetic brain tumors
...dictors of hereditary gliomas, researchers hope to uncover important genetic information that may lead to improved treatment and prevention strategies. Although only five percent of all brain tumors are inherited, this area of research is relatively neglected, but vital, for affected patients, said Bondy, ...Some patients stop needing antidepressant medication after having plastic surgery
... use of antidepressants. "We have just begun to uncover the various physical and psychological benefits of plastic surgery," said Dr. Freedman. "By helping our patients take control over something they were unhappy about, we helped remove a self-imposed barrier and ultimately improved their self-esteem."...Scientists find 'chemo brain' no figment of the imagination
...at mechanisms cause it. More studies are needed to uncover how the damage occurs and whether modification of chemotherapy drugs could prevent it. The National Cancer Institute recently awarded a five-year grant to oncologist Dr. Patricia Ganz, who is organizing a long-term study on chemo brain of a larger g...Non-steroidal anti-inflammatory drugs (NSAIDs) and congenital anomalies
...tes status. They performed statistical analyses to uncover any associations between the congenital abnormalities and the mother's use of NSAIDs during the first trimester. Among the 1056 women who filled a prescription for NSAIDs early in their pregnancy, 8.8 percent had babies with congenital anomalies. ...COX-2 inhibitors prescribed to reduce gastrointestinal toxicity prior to the market withdrawals
... inhibitor NSAID. Then, clinical studies began to uncover evidence that COX-2 inhibitors and other non-selective NSAIDs may increase the risk of heart attack and stroke. Spurred by these findings and other safety concerns, 2 of the 3 FDA-approved coxibs rofecoxib, known to consumers as Vioxx, and valdecox...Researchers uncover how prostate cancer cells defy death
...nior researcher. The goal of the research was to uncover how prostate cancer cells become resistant to treatment that lowers levels of male hormones such as testosterone, which the cells normally need to survive. They found that a protein known as BAD is involved in three different survival strategies used...'Medical Spanish' course helps physician assistants examine, communicate with Hispanic patients
...ol, has helped Jill Conway, a physician assistant, uncover medical histories and perform physical exams in Spanish. It is knowledge that has enhanced her relationship with Spanish-speaking patients and improved the medical care they receive. "Patients feel comfortable in sharing their symptoms, and I can ...JCI table of contents: July 3, 2006
...hen and colleagues from the University of Aberdeen uncover how CSF flow is regulated throughout the brain. The Sylvian aqueduct is a canal between two cavities of the brain, through which CSF passes. In most vertebrate species, a gland (known as the subcommissural organ or SCO) at the entrance to this canal ...Mouse model aids discovery of novel melanoma metastasis gene
...s array-CGH (comparative genomic hybridization) to uncover structural abnormalities of the chromosomes of cancer cells. In one common form of abnormality, bits of DNA have been overcopied (amplified) or, conversely, have been lost (deleted), and these "copy number alterations" are key events in the developme...Older blood associated with worse outcomes after repeat heart surgery
... no large, randomized clinical trials conducted to uncover links between age of transfused blood and patient ...ictors of mortality. The study was not designed to uncover the actual physiological mechanisms that cause the observed health problems, Bennett-Guerrero said. ...Indiana seed fund invests in breast cancer detection startup company
...like the Indiana University School of Medicine, to uncover potential businesses opportunities and match them with the resources they need to grow."...Blacks hit hardest by HIV infection among nation's young adults
...er of cases three it might have been possible to uncover the identity of those who tested positive. Morris said the results of the study parallel the racial disparities for other sexually transmitted diseases seen in CDC data. For example, rates of gonorrhea are about 17 times greater among black youth, ...