AACR celebrates 20th anniversary of minority scholar awards
...rds, this program was expanded to further meet the varied needs of minority scientists and is known today as the AACR Minority Scholar Awards in Cancer Research program. Since 1985 the AACR has received generous funding from the Comprehensive Minority Biomedical Branch of the National Cancer Institute to ...Six organizations vie for INFORMS 'science of better' innovation prize
...omising potential anticancer agents but they carry varied risks of toxicity; although rarely occurring, the combination of toxicities can result in death. Eli Lily was forced to halt clinical development of its antifolate ALIMTA, despite observed anti-tumor activity and more than $300 million invested. Op...Measuring enzymes at end of cancer pathway predicts outcome of Tarceva, Taxol
...sed 10 different human breast cancer cell lines to varied doses of Tarceva and then measured activity of the CDK enzymes. They found that tumor cell death was significantly dependent on whether CDK2 activity was repressed. They then double checked those findings by "putting CDK2 back," Ueno says. "We found ...Patients' lives at risk from substandard drugs say heart specialists
...safety of medicines. The activity of the remainder varied from 86% of the claim on the label right down to just a fifth. European Pharmacopaeia demands activity of 90111%. There were also differences in composition and purity. Said Dr Hermentin: "The dose of fibrinolytic agents such as streptokinase must b...High risk of second cancers in survivors of childhood soft tissue sarcomas
...k of second cancer, but estimates of the risk have varied widely, ranging from three to thirteen times the risk among the general population. Moreover, due to the small size of many previous studies, few have evaluated risk by type of soft tissue sarcoma or have estimated risks for specific second cancers. ...The World Congress on Cornelia de Lange Syndrome in Italy
...i-disciplinary interaction to address the many and varied problems which the condition presents. Therefore, the Conference foresees two participation levels: in fact, the Conference will be divided in Professional Days organised from 16th to 17th June and in the Families Conference from 17th to 19th June (...Little evidence found for IVF as most effective infertility treatment
...ver, that the studies in the review were small and varied considerably in their quality, definitions of unexplained infertility and follow-up periods. "Until more evidence is available, IVF may not be the preferred first line of treatment for these [infertile] couples and it might be appropriate to continue...Risk of womb cancer varies according to the type of HRT used
...s also found that among HRT users the risk of womb varied according to bodyweight when compared with women who had never used HRT. In women who were not overweight, a form of HRT, called cyclic-combined HRT, also increased the incidence of womb cancer. In obese women (who normally have a substantially highe...Diabetes and pizza: Slow and steady insulin delivery wins the race
...of the administration of the insulin, however, was varied each day. On day one, all of the insulin was given immediately prior to eating the meal. On day two, half of the insulin was given in one dose immediately before the meal with the other half given slowly via the continuous insulin pump over the subse...Mayo Clinic first to use pharmacogenomics to treat inherited kidney disorder of children
...c researchers now have both an explanation for the varied response and a way to predict who will respond to vitamin B6 therapy. By studying 23 patients' genetic profiles and their response rates to various dose levels of vitamin B6, the researchers found that a specific gene mutation governs how a patient w...Drug safety in the doctor's office: Nearly half of patients have lapses in monitoring
..., though it is important to note that the findings varied based on the type of drug,. The researchers conclude that although lapses in drug safety monitoring in the outpatient setting are common, further research is needed to determine to what extent this failure to monitor results in actual medical problem...Children with autism have distinctly different immune system reactions compared to typical children
...ystem responses to PHA, in contrast, produced more varied cytokine levels: Higher levels of certain cytokines and lower levels of others. According to Van de Water and Ashwood, these studies illustrate that under similar circumstances, the cytokine responses elicited by the T-cells, B-cells, and macrophag...Gender and sexual orientation influence preference for human body odors
...of underarm sweat collected from 24 odor donors of varied gender and sexual orientation. Subjects made four comparisons, evaluating and chosing between odors from (i) heterosexual males versus gay males, (ii) heterosexual males versus heterosexual females, (iii) heterosexual females versus lesbian females,...Your heart could indicate whether you have kidney problems
...ex, different cardiovascular risk factors can have varied impact on kidney function. "Studies show that the mechanisms underlying renal function abnormalities in the general population are limited," states Paul E. De Jong, corresponding author of the study. "As presently many subjects present with ESRD wit...New preoperative chemotherapy and radiation regimen yields encouraging results for sarcoma
... of the uterus. "Soft-tissue sarcoma tumors are varied and often complicated, so multidisciplinary care by an experienced sarcoma team is important to successful treatment," said Ryan, also an assistant professor of medicine (hematology and medical oncology) in the OHSU School of Medicine. "Surgical, ort...Chemo-radiation therapy treatment gives head-and-neck cancer a 1-2 punch
...of-life issue for those with head-and-neck cancer, varied depending on the institution conducting the therapy. About 14 percent of patients at experienced institutions reported severe side effects compared to 51 percent of patients at inexperienced institutions, reflecting the importance of expertise. The N...Biologic therapies for bowel disease show promise in clinical trials
...tive colitis are serious and complex diseases with varied treatment options. Unfortunately, the available therapies are not effective in many patients.," said John Johanson, M.D., of the University of Illinois. "These findings deliver promising news for patients who do not respond to currently available t...The link between physical activity and ovarian cancer
...xamination of whether activity-related cancer risk varied by tumor type. Results showed that for moderate recreational activity there was a decreased risk of certain types of ovarian tumors but not for others. No previous studies had examined the relationship between tumor type and physical activity. Physic...Small, open-label study shows potential use of novel antibiotic rifaximin for Crohn's disease
...inical index of Crohn's Disease severity. Patients varied in age from 17 to 83 and had an initial Harvey Bradshaw index ranging from 6 to 16 (mean 10.9). Following the treatment with rifaximin (400 mg twice daily), the Harvey Bradshaw index of these patients decreased significantly, range 1 to 7 (mean 3.8)...... India, China and Indonesia. "X-ray use per capita varied by a factor of three between less and more developed nations while MR and CT use varied by a factor of 100," Dr. Schweitzer said. When income was factored into the equation, some of the wo...