Draining away brain's toxic protein to stop Alzheimer's
...tream before the cholesterol can glom onto a blood vessel and cause problems with blood flow; in the same way, LRP-IV lowers amyloid-beta and indirectly lowers levels of amyloid-beta in the brain. It was more than a decade ago that Zlokovic first identified LRP, a molecule that acts like an escort service...Pathway links inflammation, angiogenesis and breast cancer
... inactivated also were found to have greater blood vessel density - a measure of angiogenesis. The researchers tested the theory by analyzing breast cancer tumors from 116 patients. They found breast cancer patients whose tumors had the TSC1/TSC2 tumor suppressor complex blocked by phosphorylation did not...Metabolic study in mice could lead to 'good cholesterol' boosters
...metabolism of HDL-C. LDL-C can build up in blood vessel walls, increasing the risk of heart disease or stroke. By contrast, HDL-C tends to carry cholesterol away from the arteries to the livera process known as reverse cholesterol transportwhere it is broken down and then eliminated from the body. Exist...Statin drugs may delay progressive artery damage in children
...h FH, which reflects an increased stiffness of the vessel wall. This is the first sign of atherosclerosis, said Dr. Hutten, an assistant professor of clinical epidemiology at the University of Amsterdams Academic Medical Centre in the Netherlands. When Hutten and colleagues began their long-term trial, sev...UK scientists set their sights on cure for AMD
...ere has been some success in controlling new blood vessel formation in wet AMD, but these approaches are only suitable for certain patients and are often only temporary. Thanks to a 4 million donation from a US private donor, the London Project will now be able to assemble the necessary spectrum of scient...USC researchers show that molecular markers predict tumor recurrence
...icient therapy. Angiogenesis refers to the blood vessel formation that provides nutrients and oxygen to cancerous growths. Researchers analyzed blood specimens that were obtained at USC medical facilities between 1999 and 2007, testing whether a specific pattern of polymorphisms in 33 genes involved in ca...Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
...te blood cells from binding to the inside of blood vessel walls. Harnessing adiponectin's properties, the sc...uggest, may someday help protect against the blood vessel damage so prevalent in patients with obesity and diabetes. Reporting June 1, 2007 in the Journal ...New biodegradable magnesium stents for coronary arteries
...atients. They found that the diameter of the blood vessel within the stent (in-stent acute gain) increased b...hey remain present but have been absorbed into the vessel walls, with the space left behind "filled in." The magnesium is eventually replaced by calcium and p...Scripps Research awarded $17 million for adult stem cell use to treat eye diseases
... that the stem cells migrate to sites of new blood vessel formation, where they can become blood vessel cells ("endothelial" cells) or vessel-associated cells such as microglia. The endothelial cells can ...Mercury's link to heart disease begins in blood vessel walls
...ggers a process leading to plaque buildup in blood vessel walls. The study examined three forms of mercury...anges in the behavior of cells that line the blood vessel walls and that can lead to cardiovascular diseases. The study also suggests that chelation therapy...New insights into chronic inflammation and atherosclerosis
...c disease and smoking as independent predictors of vessel wall inflammation. The vascular inflammation might...s were larger in size. In the middle layer of the vessel wall (the media), MCIs were detected only in patients with inflammatory rheumatic disease. What's m...Withdrawn MS drug returns to market
...ibody that prevents leukocytes from crossing blood vessel walls into tissues such as the brain and spinal cord. The drug may also benefit secondary lymphoid organs, such as lymph nodes and the spleen, and inhibit reactivation in the central nervous system. It has been shown to significantly reduce leukocyte...To get blood pressure under control, combination of medicines may be best
...ime, uncontrolled blood pressure affects the blood vessel walls, encouraging the growth of weak spots called aneurysms and the formation of narrowed and inflamed areas that can lead to clots that can break off and cause heart attacks and strokes. Only 30 percent of Americans who have high blood pressure,...JCI table of contents -- May 17, 2007
...ULAR BIOLOGY Endothelial progenitor cells mend vessel damage with a little help from EphB4 Vascular ...tors cells (EPCs) is capable of boosting new blood vessel growth in ischemic tissues, however this approach has been limited by the fact that few of the injec...Higher intake of fish and vitamin D levels linked to lower risk of age-related macular disease
...nce processes involved in the development of blood vessel and nerve-related diseases of the retina, the auth...pounds that promote cell survival and proper blood vessel function, reduce inflammation and maintain energy balance. "These results and those from other obs...A self-fulfilling prophecy in bleeding stroke?
...e, or a "bleeding stroke." Caused by a burst blood vessel in the brain, ICH kills a quarter of patients in two days, and up to half of them within 30 days. And there's no approved specific medical treatment for it -- though people can recover with specialized hospital care. Figuring out which ICH patient...Experts debate role of stenting, bypass surgery in left main coronary artery disease
...cal artery. Trusting treatment of such a critical vessel to percutaneous coronary intervention (PCI) is anathema to some. To others, it is the reasonable next step, given recent advances in stent technology. At the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interven...Employee health program improves blood pressure, diabetes control
...program that focused on preventing heart and blood vessel disease, said Sharon A. Clark, D.H.Sc., lead author of the study and JEA's health promotion specialist. "With an aging workforce, we were concerned with making a change to the modifiable risk factors for cardiovascular disease for our employees," Cl...Patients with 'bleeding' strokes less likely to get prevention treatment
...od. A subarachnoid hemorrhage occurs when a blood vessel on the brain's surface ruptures and bleeds into the space between the brain and the skull (but not into the brain itself). Bleeding strokes have a much higher fatality rate than strokes caused by clots. Get With The GuidelinesStroke is an American H......III patients. In response to injury of the blood vessel lining, blood platelets adhere to fibrin, endothelial cells lining the vessel wall, and to each other via adhesion receptors known as integrins, to form what is often referred to...