Survivors of childhood polio do well decades later as they age
...lls in the spinal cord; bulbar polio, in which the virus attacks motor neurons in the brainstem; and bulbospinal polio, a combination of spinal and bulbar polios. The effects of polio run the gamut from a complete return to normal function to paralysis of limbs to acute death. Following the illness, most p...Molecular switch may turn off immune cells that target HIV
...e viruses, but in chronic infection high levels of virus appear to overwhelm and exhaust CD8 cells. Recent studies in mice by Rafi Ahmed, PhD, of Emory University School of Medicine and Gordon Freeman, PhD, of Dana-Farber Cancer Institute both co-authors of the current report indicated that PD-1 is over...Study shows long-term health effects from West Nile illnesses
...than a year after being diagnosed with a West Nile virus infection, half of the patients have ongoing healt...gitis. People can become infected with West Nile virus when they are bitten by a mosquito that has previously bitten an infected bird. The virus was first ...Researchers discover how acid reflux leads to esophageal cancer
...okers or of liver cancer among chronic hepatitis-B virus carriers. In order to prevent the progression, it may be necessary to increase treatment with proton pump inhibitors in patients with Barrett's Esophagus, the authors write. "Elucidating the pathways leading from acid exposure to increased ROS p...Polio outbreak from oral vaccine identified -- and controlled -- in China
...and colleagues in Beijing and elsewhere, involving virus isolated from an outbreak in Guizhou province in r...n had been immunized against polio. Based on the virus strain's known rates of mutation, the finding indicated that the isolates had been circulating for l...Updated International AIDS Society guidelines recommend new goal of undetectable viral load
...atment goal of reaching undetectable levels of the virus ( Recent clinical trials have convinced the auth... the cornerstone to achieve undetectable levels of virus for treatment-experienced patients. "Maintaining undetectable viral load is the best way to achiev...Rapid expansion of HIV treatment services in Africa feasible, with good patient outcomes
...population is infected with human immunodeficiency virus 1 (HIV 1), including 22 percent in the capital city Lusaka. In 2003, more than 90,000 Zambians died of HIV disease. Historically, only the wealthiest citizens have had access to antiretroviral therapy (ART) for HIV through private medical practices. ...No advantage for four-drug antiretroviral regimen vs. three-drug for initial treatment of HIV-1
...re for initial treatment of human immunodeficiency virus 1 (HIV-1) infection is a three-drug antiretroviral regimen, which can suppress viremia (presence of HIV in the blood), increase CD4 cell counts, delay clinical progression, and improve survival, according to background information in the article. Som...Panel updates guidelines for treatment of adult HIV infection
...million persons living with human immunodeficiency virus (HIV), according to background information in the article. Guidelines for antiretroviral therapy are important for clinicians worldwide given the complexity of the field and the varied clinical situations in which these agents are used. To provid...Study shows promise for simplified treatment of HIV infection
...es of simpler therapies for human immunodeficiency virus type 1 (HIV-1) infection. Treatment cessation, int...virologic suppression (cessation of detectable HIV virus replication) would not markedly increase the risk of virologic failure. Protease inhibitors, such as...HIV infection requires an accomplice: B cells with special protein direct HIV to T cells
...ls, a finding that reveals yet another pathway the virus uses in its insidious attack on the immune system,... not become infected, B cells nonetheless harbored virus that was transmissible to T cells for up to two days. HIV had little effect on the T cells when B ce...T cells activated to fight HIV basis for dendritic cell therapeutic vaccine
...y other cells of the immune system in fighting the virus unique to that individual. At the XVI Internatio...notherapy, is custom-designed to target the unique virus that has evolved in each individual being treated. A patient's own dendritic cells together with the...Clinical trial evaluates first-line approaches for treating HIV
...se transcriptase inhibitor (NNRTI), suppressed the virus to undetectable levels in more participants than t...xperienced virologic failure a rebound in the HIV virus load to detectable levels during the study compared to the efavirenz group. After 96 weeks of treat......is unusual about CTVT in dogs, however, is that no virus is involved the cancer itself is effectively passed on. In a paper published in the journal Cell, veterinarian researcher Dr Claudio Murgia conducted forensic DNA tests on tumour tissues from 16 dogs affected by CTVT. The dogs were being treated ...Actor Richard Gere presents altarpiece highlighting South African response to AIDS
...worldwide fight against the human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS), the first cases of which were reported in 1981 by UCLA physicians. The Art | Global Health Center at UCLA serves as the umbrella for the international MAKE ART/STOP AIDS project, a network of ar...Multiple Sclerosis in genetically susceptible twins is augmented by the northern environment
...t exposure to the sun interrupts whatever effect a virus has," Mack says. ...Sub-Saharan Africans with HIV may achieve favorable levels of antiretroviral therapy adherence
...improved the health of many human immunodeficiency virus (HIV) positive individuals who otherwise would have died. However, treatment effectiveness relies on sustained adherence, which is a serious challenge to those receiving ART, according to background information in the article. The regimens are often ...Researchers find 'secret weapon' used by SARS virus
...se it infected. When scientists identified the virus that caused this sudden acute respiratory syndrome, they classified it as a coronavirus--a virus family whose other members cause many common colds. But to there was nothing common about the lethal...New bird flu drug promises to beat the problem of resistance
...extent of resistance the ability of the influenza virus to withstand drug treatments - becomes more widely...eventually dying. This suggests that the influenza virus was able to rapidly develop resistance to the drug. In another study in Japan, the virus develope...New hope in cancer vaccines emerges as novel therapies are developed and tested
...system into thinking it is attacking bacteria or a virus (see sidebar). They are designed to strengthen the.... D. Anderson, where the cells are infected with a virus that carries a gene that activates the immune system. When the cells are given back to the patients,...