The Cochrane Library newsletter, 2005, issue 2
...hbrush. These results show that many people may be wasting money on toothbrushes they believe will clean their teeth better, when actually a much cheaper traditional brush would do the job just as well. For the best possible cleaning performance consumers should opt for an electric brush with a rotating-osci...Exercise training in ordinary people affects the activity of 500 genes
...atients with Duchenne's muscle dystrophy, a muscle wasting disease. Most of the muscle genes previously claimed to be specific for Duchenne were also activated with endurance training. Maybe the musculature in Duchenne patients strive to adapt in part similar to what happens in training. The results from thi...Active vaccine prevents mice from developing prion disease
...hich include scrapie, mad cow disease, and chronic wasting disease -- is on the horizon, many research groups...ere is ever a more significant outbreak of chronic wasting disease and if this disease were found to be transmissible to humans, then we would need a vaccine l...Scientists observe infectious prion proteins invade and move within brain cells
...seases include scrapie in sheep and goats; chronic wasting disease in deer and elk; mad cow disease in cattle; and Creutzfeldt-Jacob disease in humans. Under the direction of Byron Caughey, Ph.D., at the Rocky Mountain Laboratories (RML), and Marco Prado, Ph.D., at the University of Minas Gerais in Belo Hori...Variant prion protein causes infection but no symptoms
...e in people, mad cow disease in cattle and chronic wasting disease in deer and elk. Now, new research suggests that a variant form of abnormal prion protein--one lacking an "anchor" into the cell membrane--may be unable to signal cells to start the lethal disease process, according to scientists at the Rocky...Discovery may prevent life-threatening wasting disease in patients with chronic kidney disease
...ombat cachexia -- severe malnutrition and physical wasting away -- in children and adults with chronic kidney disease (CKD). The study is published in the June issue of the Journal of Clinical Investigation. Although the exact cause of cachexia -- a common life-threatening complication of CKD, cancer, AIDS a...Hopkins AIDS experts issue warning about global efforts to provide drug therapies
... did not sway public opinion that the military was wasting its share of medication. "While the lack of a plan is the worst-case scenario, even a plan with no public input can backfire if it fails to win local support," says McGough, a research fellow at Hopkins' Institute of the History of Medicine. "It is ...Sports doping explored during half-day symposium, Aug. 30
...n growth factor compounds designed to treat muscle wasting disease might be used to boost muscle mass; erythropoietin (EPO), a hormone that regulates red blood cell production, might be genetically engineered to increase endurance; and 'PGC-alpha, a gene involved in muscle signaling, could be used to activat...Autoimmune overload may damage HIV-infected brain
... blood cells, perhaps one day countering the brain wasting that will affect as many as 15 percent of the nearly 40 million people around the world who are infected with the virus. The study is a collaboration among researchers at the University of California at Irvine, the University of Florida at Gainesvill...Tuberculosis, infertility may have influenced George Orwell's writing
... perhaps drawing on his firsthand knowledge of the wasting effects of tuberculosis. Orwell's poor health and apparent infertility (based on his own musings in his letters as well as the medical evidence linking some respiratory ailments to infertility) probably contributed to the despondency in his writing. ...Which drugs should health plans cover?
...rection--either restricting necessary treatment or wasting consumers' premiums on expensive medicines that offer no real advantage? These issues are addressed by experts from Group Health in an article in the October 2005 issue of the Journal of General Internal Medicine. The piece presents five principles t...UQ scientists break new ground in fight against infection & chronic disease
...ory bowel disease. They are also behind the muscle wasting experienced by patients with cancer. Chronic inflammatory disorders are a substantial burden in social and economic terms for the Australian community. Arthritis alone afflicts 3.4 million Australians and the financial costs were more than $19.25 b...Columbia receives up to $15 million from Spinal Muscular Atrophy Foundation
...genetic, motor neuron disease characterized by the wasting of skeletal muscles due to progressive degeneration of nerve cells in the spinal cord. Loss of function leads to premature death due to respiratory problems; half of its victims die before reaching age two. The SMA Foundation estimates that there a...What's the link between astronauts and osteoporosis?
...timulation that builds bone and prevents bone from wasting away exercise also plays a key role. The publication cited an experiment in which "terranauts", who spent three months lying flat and not doing any exercise, lost up to 15% of their bone mineral density. Pre-registration to the International Osteopo...Anabolic steroid use increases heart attack risk and causes liver damage
...d the effects of anabolic steroids on men with HIV wasting disease. The results have implications for athlet...g. "This is good news for people with devastating wasting illnesses, who suffer from the effects of loss of muscle mass and whose most immediate risk is that ...Injection of synthetic polymer may improve facial wasting syndrome associated with HIV
... authors write. This facial lipoatrophy or facial wasting may lead to anxiety, depression, self-image proble...days. The 16 patients with the most severe facial wasting received two additional injections after 75 and 90 days. The patients' facial atrophy began to impro...UI research aims to help patients with spinal cord injury
...for astronauts who experience bone loss and muscle wasting similar to SCI patients due to long periods spent in low gravity....Five surprising facts about starvation that could change the international agenda
...s with the highest child mortality rates and child wasting rates. Based on their assessment of the data, the ...political instability, does not prevent or resolve wasting in children. When the authors compared countries without recent conflict to countries that have rece...Taking the wrinkles out of motoneuronal disease
...ng disorders which lead toprogressive weakness and wasting of muscles. Many of the diseases are incurable. Dr Meunier is developing botox to selectively deliver drugs to motoneurons to directly treatmotorneuron diseases. "I first became interested in investigating neurotoxins because they are fantastic m...Prion disease infectivity causes heart damage in mouse study
...w theories about the effects of these deadly brain wasting diseases," says NIH Director Elias A. Zerhouni, M....e in humans, mad cow disease in cattle and chronic wasting disease in deer and elk. The cause of prion diseases, still under debate, may be abnormal aggregated...