Using coxibs and NSAIDs to treat osteoarthritis
...y now exists as to the safest and most efficacious way of treating the disease, particularly with respect to use of NSAIDs, both non-selective and selective (so-called COX-2 selective agents or coxibs). Adverse reactions related to the gastrointestinal tract, particularly with the non-selective NSAIDs, ...Patient-centered approach can backfire
...t patient preferences or attitudes could go a long way toward creating a healthy and mutually satisfying patient-physician relationship." The findings already apply to patients. Christensen said it's a good idea for patients to look for doctors who match their style, either by reputation or word of mou...Anemia and tropical diseases; Is pharmacogenomics ready for the clinic?
...chers argues that measuring anemia could be a good way of monitoring the burden and control of neglected tropical diseases (NTDs) such as schistosomiasis and intestinal worms. Imelda Bates (Liverpool School of Tropical Medicine, UK) and colleagues say that the prevalence of anemia in a community might ...1 of 2 pediatric kidney disease research centers in world established
...to-bedside approach to translational research as a way of expediting clinical cures in all disciplines. Researchers at the Center are working to delineate the genetic and cellular mechanisms of childhood kidney disease and its progression and develop unique therapies that will limit or even cure genetic ...Disability payments may spur drug abuse
...ing out aid payments over several weeks could be a way to relieve some of the stress on hospitals and health care workers who struggle to handle the monthly surge. The analysis found that in California, the 23 percent increase in drug-related hospital admissions that occurs in the first five days of any...Draining away brain's toxic protein to stop Alzheimer's
...ochester Medical Center show how the bodys natural way of ridding the body of the substance is flawed in people with the disease. Then the team demonstrated an experimental method in mice to fix the process, dramatically reducing the levels of the toxic protein in the brain and halting symptoms. The team...MRI finds breast cancer before it becomes dangerous
...iologist Professor Christiane Kuhl explains. 'That way we prevent the development of a disease that is often life-threatening.' However, there are different forms of intraductal carcinomas: the less aggressive (low-grade) and highly aggressive (high-grade) DCIS. Whereas low-grade DCIS is relatively inert...Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
...ed, the research might also help scientists find a way to prevent the bone-marrow cells from invading or to identify markers that would allow an earlier diagnosis for Barretts esophagus, which doesnt usually have symptoms. ...New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
...ancers lose sensitivity because they have found a way to keep growing in the absence of estrogen. Pre... Using this discovery, Clarke also hopes to find a way to reverse resistance to anti-hormonal therapies, making it possible for women to continue treatment...NIH scientists target future pandemic strains of H5N1 avian influenza
...ump from birds to humans, they have come up with a way to anticipate how that jump might occur and ways to respond to it. Now we can begin, preemptively, to consider the design of potential new vaccines and therapeutic antibodies to treat people who may someday be infected with future emerging avian in...Preventive treatments in elderly people needs rethinking
...is weeks BMJ. They call for a more sophisticated way of assessing the benefits and harms of preventive treatment in elderly people. Preventive health care aims to delay the onset of illness and disease and to prevent untimely and premature deaths, say Dr Dee Mangin and colleagues. But concerns about ...'Heroes of Chemistry' honored for medical, energy, environmental breakthroughs
...welfare and progress of humanity" in a significant way in the past decade. The scientists were part of multidisciplinary teams representing Chevron Phillips Chemical Company LP, DuPont, with partners Genencor International and Tate & Lyle, ExxonMobil Research and Engineering Company, Novartis AG and Pf...Not all 'drug-related deaths' are 'drug-related'
...drug abusers. So these figures may not be the best way of monitoring the performance of Drug and Alcohol Action Teams, a study published in the online open access journal Substance Abuse Treatment, Prevention and Policy suggests. DRDs are currently used to help evaluate the success of Drug and Alcohol ...Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
...ase had been previously masked as the conventional way of assessing levels of thiamine status was to measure the activity of an enzyme called transketolase in red blood cells. Past studies had seen normal activity of this enzyme and assumed normal levels of thiamine when in fact the normal enzyme activit...New research discovers independent brain networks control human walking
...rent conditions. As we understand more about the way the brain learns, relearns and adapts in relation to motor skills, physical therapy professionals have a vastly expanding toolbox from which to tailor therapeutic interventions, explains Gary Goldstein, MD, President and CEO of the Kennedy Krieger In...Metabolic study in mice could lead to 'good cholesterol' boosters
...larly in humans, the new discovery could point the way to therapies that protect against heart disease by boosting concentrations of the beneficial high-density lipoprotein cholesterol (HDL-C). By and large, the medicines now available lower levels of the bad low-density lipoprotein cholesterol [LDL-C]...Miniature implanted devices could treat epilepsy, glaucoma
... a particular part of the brain starts firing in a way that is abnormal," Irazoqui said. "Being able to record signals from several parts of the brain at the same time enables you to predict when a seizure is about to start, and then you can take steps to prevent it." Data from the implanted transmitte...Theory of facial aging gets a facelift from UT Southwestern researchers
...lowed skin and wrinkles. This is a revolutionary way of viewing facial anatomy. It not only tells us how we age, it shows us why we age the way we do, and why every part of the face, from the eyelids to the cheeks, ages differently, said Dr. Ro...Sports concussion research using fMRI provides insight for safe return-to-play decisions
...sed public awareness and significantly changed the way sports concussions are managed. Importantly, much of this research has included data that proves the usefulness of objective neuropsychological test data as part of the comprehensive clinical evaluation to determine clinical recovery following concus...Novel candidate biomarker for heart failure also strongly predicts risk of death
...kers yield to better adjust therapies in the same way that antibiotics are chosen based on the organism causing the infection that would be revolutionary. A condition in which the heart muscle is damaged and cannot pump blood efficiently, heart failure is a major cause of cardiac death. Diagnosis ...