Pathway links inflammation, angiogenesis and breast cancer
...upply tumors. The chain of events, painstakingly worked out by Hung, first author and doctoral student Dung-Fang Lee, and colleagues works like this: TNFa activates IKK, which as a kinase works by attaching phosphate groups to other proteins. IKK phosphorylates tuberous sclerosis 1 (TSC1) block...Some women benefit more from exercise when emphasis is on health, not appearance
... range for body size. The women reported that they worked out at moderate or vigorous intensity about 3.3 times a week. The women participated in one of four 45-minute step-aerobics classes. The same instructor taught each class, although she emphasized health over appearance in two of the classes. In the...'Heroes of Chemistry' honored for medical, energy, environmental breakthroughs
...n 1982. David Olson, Ph.D., has retired, having worked in ExxonMobil's Central Research Laboratory for more than 35 years. He received a Ph.D. in physical chemistry from Iowa State University in 1963. Novartis AG, Basel, Switzerland, developed Exjade (deferasirox) as a new treatment to help patients...Michigan-CDC study supports value of social restrictions during influenza pandemics
...ial infrastructure. By better understanding what worked in the past, we can better prepare for the future, says senior author Martin Cetron, M.D., director of the CDCs Division of Global Migration and Quarantine. Communities that were most successful during the 1918 pandemic quickly enacted a variety of m...Controlling prescription drug expenditures: a case report of success
... collaboration between physicians and the hospital worked well to ensure not only that cost savings could be achieved but also that employees received pharmaceuticals that are shown by evidence to be effective....Rutgers professor Bart Krekelberg is named 1 of 20 US Pew Scholars for 2007
...joining the Rutgers University faculty in 2005, he worked as a post-doctoral fellow at Ruhr University, in Bochum, Germany, and as a research associate at the Salk Institute in La Jolla, California. His recent publications include Interactions Between Speed and Contrast Tuning in the Middle Temporal Area: I...Shining light on pancreatic cancer
...a normal biopsy. In both studies, the techniques worked regardless of age, tumor size, smoking history or tumor location, although the researchers hope to use the next trial phase to test individuals with serious pancreatic diseases that are not cancer to see if the changes are truly unique to cancer. Eve...K-State researcher working on a way to make snack foods with extra fiber
...have a better physical quality." The researchers worked with the bakery science lab at K-State's departmen...nriched flour that wasn't precooked. The team then worked with K-State's sensory analysis team to conduct taste tests. Subjects were offered vouchers for K-St...Extended duration work shifts risky to the safety, well-being of medical interns, patients
... errors and the number of extended duration shifts worked in a month were both significant predictors of stress. Compared to months in which no extended duration shifts were worked, interns working five or more extended duration shifts had seven times greater odds of reporting at least one fatigue-related ...Split the difference: Pill-splitting study looks at cost-saving step that could be used by millions
...ctors records. In recent years, pharmacists have worked to determine which tablets can be safely split, and which such as drugs that exit the body quickly, or that have time-release coatings cannot. Cholesterol-lowering drugs called statins are among the most widely-used classes of medicines, with te...New drug shows promise in treatment of advanced thyroid cancer
...ngiogenesis. The study confirmed that the drug worked as predicted. Treatment significantly reduced the presence of soluble VEGF receptors, VEGFR2 and VEGFR3, in blood. Levels of VEGF in the blood increased, suggesting that this growth factor was compensating for angiogenesis inhibition by axitinib. ...Old memory traces in brain may trigger chronic pain
..., such as aspirin and morphine derivatives, havent worked very well. A Northwestern University researcher has found a key source of chronic pain appears to be an old memory trace that essentially gets stuck in the prefrontal cortex, the site of emotion and learning. The brain seems to remember the injury...Stanford researchers track human stem cells transplanted into rat brain
...Guzman, MD, wanted to make sure that the particles worked in human cells as well. "I think it's critical that we are applying this technique in human stem cells that can be used in human clinical trials," said Guzman, who is lead author of the paper. He said that because they chose to work with those cell...AMPAKINE compounds a new potential treatment for respiratory depression
...he respiratory distress quickly resolved. The drug worked in both newborn and adult rats. Interestingly, the drug on its own did not affect blood flow in animals not treated with the sedative drugs, nor did administration of the drug cause noticeable arousal in the animals. Greer concluded, in a study pu...Brain inflammation may be friend, not foe, for Alzheimer's patients
... In the original development of his mouse, Shaftel worked closely with Stephanos Kyrkanides, D.D.S., Ph.D., associate professor in the Eastman Department of Dentistry and an expert on using a class of viruses known as lentiviruses for use in gene therapy. The team used a lentivirus to boost levels of IL-1 b...Veterinarians at increased risk of avian influenza virus infection
...ared with the control group, the veterinarians who worked with birds had significantly higher levels of antibodies in their blood against the H5, H6 and H7 avian virus strains, indicating previous infections with these viruses. The infections were likely due to the mild forms of avian influenza virus that h...Dr. Eli Peli of Schepens Eye Research Institute elected SPIE fellow
... as well as modeling of normal vision. He has also worked with the National Institute of Health on the development of public information and education. His service to SPIE includes chairing sessions relating to visual representation and processing, presenting a continuing education seminar on vision models ...Policy changes have direct effect on nursing home care
... other sources. She examined the hours that nurses worked in nursing homes in 2002 and analyzed the data against two variables: Medicaid reimbursement rates and the range of acuity in patient care. Medicaid pays for 67 percent of all nursing home residents in the United States, but only covers 51 percent...ICU nurse working conditions linked to increase in patient infections
...es of infection and skin ulcers. On average nurses worked overtime 5.6 percent of the time. These findings, reported in the June issue of Medical Care, one of the leading health care administration journals, support the notion that a systematic approach aimed at improving nurse working conditions will impro...Medical, high-energy physicists collaborate to improve PET scans
...ch atomic energy commission. Le D and Frisch had worked together almost 20 years ago to develop an instrument for the ill-fated Superconducting Supercollider. Nevertheless, "It was a complete surprise to find out that we were thinking along absolutely parallel lines," Frisch said of the ideas that Le D pr...